UV Spectrophotometric Analysis and Validation of Dapsone in Semisolid Dosage Form

Emulgel is a developing topical drug delivery technique that, if more attempt is put for the preparations with majority of topically effective drugs, will be a benefit for dermal care and cosmetic products due to its dual release control system (gel and emulsion). The direct availability of the skin as a target organ for diagnosis and treatment is a distinguishing characteristic of dermatological pharmacology. Transparent gels have grown in popularity as a crucialclass of semisolid preparations in both cosmetics and pharmaceuticals. Despite the many benefits of gels, one major limitation is the delivery of water insoluble drugs because solubility acts as a barricade and a problem arises during drug release. As a result, an emulsion-based strategy is being employed to bypass this barrier, allowing even a hydrophobic medicinal component to benefit from the special features of gels. Emulgels are dosage forms made up of gels and emulsions that have been mixed. The major goal is to generate a jellified emulsion that will reduce systemic side effects and produce a more prominent effect with fewer drug doses. Thixotropic, greaseless, good Spreadability, easily removable, soothing, soluble in water, long shelf life, bio-friendly, translucent & appealing look are only a few of the benefits of emulgels for dermatological use. As a result, emulgels can be utilize as a good topical drug delivery mechanism than the currently existing traditional systems.

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Overview on Emulgel and their marketed Formulations

Sanjay Patil.,

Arjun Patil.,

R. Shah

2023

AJPS

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Background: Emulgel is a topical preparation prepared by the mixture of an emulsion and a gel. Emulgel is considered as one of the most important topical delivery systems because it consists of two release control systems, i.e., a gel and an emulsion. The primary intention of this new topical delivery system is to deliver hydrophobic drugs into systemic circulation through the skin. By applying a suitable statistical design, different grades of emulgel can be prepared. There are various favorable properties. Therefore, emulgel is considered as the most conventional system available in the market over other topical drug delivery systems. Objectives: In the present work an attempt was made to prepare emulgel of garlic oil and ajwain oil for enhancing its topical delivery. Material and Method: Emulgel formulation was characterized by various parameters like pH, viscosity, spredability, Extrudability, microbiological Assay.

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UV Spectrophotometric Analysis and Validation of Dapsone in Semisolid Dosage Form

Cited by 3 publications

References 5 publications

Spectrophotometric estimation of dapsone in Schiff base in its pharmaceutical preparation using charge transfer complex method

Spectrophotometric estimation of dapsone in Schiff base in its pharmaceutical preparation using charge transfer complex method

A Review on Emulgel: Improvement of Topical Absorption of Drug

Overview on Emulgel and their marketed Formulations

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