Vaccinia of the Eyelids

Abstract

counts can this be accomplished. Other important diag¬ nostic features are ( 1 ) a history of recurrent infections of the skin or mucous membranes over a period of years, possibly from infancy, (2) the presence of recurring cycles of neutropenia or agranulocytosis coinciding with these episodes, and (3) the sustained good general health of the person. Once the diagnosis is made, wise manage¬ ment of the patient can greatly ameliorate the economic consequences of a life-long periodic illness. SUMMARY AND CONCLUSIONSCyclic neutropenia in a 16-year-old girl observed over a four year period is described. Splenectomy was not followed by relief from periodic infections. No effect on the regularity of the cycles or on the degree of neutro¬ penia resulted; however, the total leukocyte count in¬ creased from an average of 3,960 before splenectomy to an average of 6,220 per cubic millimeter two and a half years later. Spontaneous relief from infections occurred during two pregnancies.