Vacuum and mesh-mediated fascial traction for primary closure of open abdomen in critically ill surgical patients (Br J Surg 2012; 99: 1725–1732)

Abstract

The catching of insects …︁. ‥ by the carnivore sundew plant (cover picture, background) can be considered a model of cisplatin uptake by tumor cells mediated by the copper transporter protein Ctr1. As G. Natile and co‐workers describe in the Communication on page 9062 ff., the extracellular methionine‐rich motifs of Ctr1, like the sticky tentacles on the sundew's leaves, entangle the platinum moiety and induce formation of an endocytic vesicle, which also resembles the trap cavity formed by the bending of the sundew's tentacles over its prey. The background photo is by Pavel Kraśenskyý.

Current Status of the Open Abdomen Treatment for Intra-Abdominal Infection

“…Delayed fascial closure, defined as fascial abdominal closure over 9 days after initial OA procedure, is often performed through a form of planned ventral hernia repair [26]. Besides the primary disease, massive transfusion (also known as overload fluid resuscitation), early presence of complications during hospitalization and nonfascial traction technique were also attributed to the postponed closure [38, 39]. Generally, a definitive fascial closure would be performed at about 6–12 months after an open abdomen.…”

Chinese Trauma Surgeon Association for management guidelines of vacuum sealing drainage application in abdominal surgeries—Update and systematic review

“…This topic included 20 related articles: one RCT, 93 and 19 were retrospective studies. 33 , 49 , 53 , 55 , 56 , 65 , 68 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 …”

“…A total of 19 articles involving VSD-related secondary intestinal injury after abdominal surgery were included, of which 2 were RCTs 143 , 144 and 17 were retrospective studies. 19 , 30 , 55 , 93 , 98 , 130 , 145 , 146 , 147 , 148 , 149 , 150 , 151 , 152 , 153 , 154 , 155 …”

“…For patients who had no intestinal fistula before surgery, the incidence of intestinal fistula was 1.6%–37% after VSD-assisted TAC. 19 , 93 , 98 , 130 , 144 , 145 , 146 , 147 , 148 , 149 , 150 , 151 In the prospective studies, two RCTs 143 , 144 compared the incidence of intestinal fistulas in TAC surgeries using VSD and absorbable mesh fixed on the abdominal fascia and found no significant differences. Among the five observational studies, Plaudis et al.…”

“…Five observational studies have shown that OA negative pressure wound treatment does not increase the incidence of intestinal fistulas. 98 , 145 , 147 , 151 , 155 Shaikh et al. 155 observed 42 cases of VSD treatment for abdominal incision dehiscence and OA over 5 years.…”