Vacuum-assisted Closure versus Conventional Wound Care in the Treatment of Wound Failures Following Inguinal Lymphadenectomy for Penile Cancer: A Retrospective Study

Denzinger, Stefan; Lübke, Lars; Roessler, Wolfgang; Kessler, Sigurd; Burger, Maximilian

doi:10.1016/j.eururo.2006.12.027

Cited by 16 publications

(17 citation statements)

References 20 publications

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“…A random-effects model was used to compare the RR between NPWT and conventional non-negative pressure dressings vulva cancers are associated with complications including seroma, SSI, lymphoceles, persistent lymphorrhoea, lymphedema, wound breakdown, significantly longer time of hospitalisation, and reinterventions. 14,[18][19][20] Breakdown of wounds with protracted secondary healing following inguinal lymphadenectomy for penile cancer was reported in up to 50% of cases. 14,21 In a meta-analysis, inguinal lymphadenectomy of lower part body melanoma was associated with overall complications of 52%.…”

Section: Discussionmentioning

confidence: 99%

“…14,[18][19][20] Breakdown of wounds with protracted secondary healing following inguinal lymphadenectomy for penile cancer was reported in up to 50% of cases. 14,21 In a meta-analysis, inguinal lymphadenectomy of lower part body melanoma was associated with overall complications of 52%. 20 Vulvectomy not only has a significant psychological impact on patients but is also complicated by complex wound failures in 26% to 85% of cases, resulting in long hospital stays and cicatrisation.…”

Section: Discussionmentioning

confidence: 99%

“…13 For proximal lower extremity soft tissue sarcomas with preoperative radiation, NPWT use at the time of resection is associated with a lower risk of wound complications and secondary operative procedures, and the duration of the treatment until complete closure of the wound is significantly shorter. 14,18 Likewise, conventional care of vulvectomy wound takes 2 to 3 months until wound recovery and is even longer when patients are of old age, obese, and have multiple cormobidities. 22,25 Using NPWT dressing immediately after vulvectomy reduces the total length of cicatrisation by approximately 16 days.…”

Section: Discussionmentioning

confidence: 99%

“…There was no tumour recurrence in the follow-up period in two studies. 12,14 Tumour recurrence included both local recurrence and distant metastasis.…”

Section: Included Study Characteristics and Details Of Study Interven...mentioning

confidence: 99%

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Oncologic feasibility for negative pressure wound therapy application in surgical wounds: A meta‐analysis

Wang

Yao

Lin

et al. 2021

International Wound Journal

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Negative pressure wound therapy (NPWT) decreases postoperative complications of various surgeries. However, the use of NPWT for oncological surgical wounds remains controversial. To evaluate the association of NPWT with oncologic recurrence in surgical wounds without residual malignancy, we analysed studies that compared NPWT with conventional non-pressure dressings for cancer surgical wounds without residual tumour by August 12, 2020.We compared tumour recurrence rates and postoperative complications between the two procedures. The six studies included 118 patients who received NPWT, and 149 patients who received conventional non-pressure wound care. The overall quality of the included studies was high based on the Newcastle-Ottawa scale score of 7.5. Tumour recurrence after NPWT was not significantly different compared with conventional non-negative pressure wound care (9.3% versus 11.4%, P = 0.40). There was no significant heterogeneity between the studies (I 2 = 3%). Although NTWT was associated with a lower complication rate compared with the control group, the result was nonsignificant (P = 0.15). Application of NPWT in oncologic resection wounds without residual malignancy revealed no difference in local recurrence and may reduce the risk of postoperative complications compared with conventional non-negative pressure dressings. NPWT can be considered an alternative method for reconstruction in challenging cases.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…There was no tumour recurrence in the follow-up period in two studies. 12,14 Tumour recurrence included both local recurrence and distant metastasis.…”

Section: Included Study Characteristics and Details Of Study Interven...mentioning

confidence: 99%

See 2 more Smart Citations

Oncologic feasibility for negative pressure wound therapy application in surgical wounds: A meta‐analysis

Wang

Yao

Lin

et al. 2021

International Wound Journal

View full text Add to dashboard Cite

show abstract

“…The presence of malignant tissue is generally viewed as a contraindication for VAC, as it stimulates cell growth [1]. There are only three reports of VAC in urology [2-4]. No treatment of intraabdominal urinary leakage, a rare but severe event in urinary diversion [5], has been reported to date.…”

Section: Introductionmentioning

confidence: 99%