Vaginal colonization with Group B beta-hemolytic streptococcus as a risk factor for post-cesarean section febrile morbidity

Minkoff, Howard; Sierra, Marcelino F.; Pringle, George F.; Schwarz, Richard H.

doi:10.1016/0002-9378(82)90781-5

Cited by 53 publications

(19 citation statements)

References 5 publications

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“…There was even a trend, without statistical significance, towards a lower preterm inci dence among GBS carriers. Our data agree with those of other authors who did not find differences in the average weight of newborns [21 ] or in the average GA [20,21 ]. In a series of 205 3rd-trimester pregnancies, the lack of an association of GBS colonization (vagina and/or throat) with preterm delivery has been reported [23].…”

Section: Discussionsupporting

confidence: 70%

“…As with PROM, our experience shows a risk increase of PROM for patients colonized by GBS similar to that reported by other authors [11,12,20], In the referenced works [11,12,20], as well as in another one [21], where this association was not found, there is only one anatom ical location studied; thus, it is not possible to determine the significance of GBS in the different locations. It is known that the frequency of isolating GBS varies for the different locations, with a colonization-descending gra dient from vulva to cervix [22], Our data, although showing a significant increment of PROM for GBS car riers (in vagina and/or rectum; RR = 1.66), reveal that the risk depends fundamentally on the cervical coloniza tion (RR = 3.31).…”

Section: Discussionsupporting

confidence: 50%

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Group B Streptococcus and Premature Rupture of Membranes and Preterm Delivery

Matorras¹,

Perea

Omeñaca

et al. 1989

Gynecol Obstet Invest

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In a population of 1,050 pregnant women the effect of maternal colonization by group B Streptococcus on premature rupture of membranes (PROM), preterm delivery, and low weight was analyzed. A significant increment was found of the prevalence of PROM for patients colonized in the vagina and/or the rectum (26.4%) versus noncarrier patients (17.8%). In vaginal and/or rectal group B Streptococcus carriers, in whom group B Streptococcus was also isolated from the cervical culture, the rate of PROM was higher (41.7%), while when the cervical culture was negative, the PROM was similar to noncarriers. There were no significant differences with respect to colonization conditions regarding the incidence of preterm delivery or the different preterm delivery indicators analyzed.

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Section: Discussionsupporting

confidence: 70%

Section: Discussionsupporting

confidence: 50%

Group B Streptococcus and Premature Rupture of Membranes and Preterm Delivery

Matorras¹,

Perea

Omeñaca

et al. 1989

Gynecol Obstet Invest

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“…The evidence that GBS is associated with maternal infections includes isolation of GBS from blood and genital specimens of women with IAI and PPE and the association of vaginal colonization with an increased risk of PPE [3,4]. A recent study examined the risk of high-density GBS vaginal colonization and IAI or PPE by evaluating women who had samples cultured within 2 weeks of delivery without receiving antimicrobial therapy [5].…”

mentioning

confidence: 99%

Maternal Peripartum Complications Associated with Vaginal Group B Streptococci Colonization

1999

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The study was done to determine the risk of clinically diagnosed intra-amniotic infection (IAI) and postpartum endometritis (PPE) associated with vaginal group B streptococci (GBS) colonization. Pregnant women were enrolled in a cross-sectional, observational study from 1992 to 1996 in Houston (n=908), Seattle (n=2676), and Pittsburgh (n=4338). Swab samples were obtained from the lower vagina of participants at admission for delivery and inoculated into selective broth and onto blood agar media. At the combined centers, 2.9% of the women (231/7922) had IAI, and 2.0% (157/7922) had PPE. The risk of IAI was higher for women with heavy GBS colonization (odds ratio [OR], 2.0; 95% confidence interval [95% CI], 1.1-3.7) than for those with light colonization (OR, 1.2; 95% CI, 0.7-1.8). The risk of GBS-associated PPE was not influenced by density of colonization (OR, 1.8; 95% CI, 1.3-2.7). These findings provide further evidence that GBS is associated with maternal intrapartum complications.

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“…Risk factors associated with early-onset GBS disease include prolonged rupture of membranes, low birth weight, preterm birth, premature rupture of membranes, heavy GBS maternal colonization and maternal pyrexia in labour [1,4,5,9]. Group B colonization of the female genital tract has been associated with chorio-amnionitis and postpartum endometritis [1,[10][11][12].…”

Section: Introductionmentioning

confidence: 99%

<i>Streptococcus agalactiae</i> (Group B Streptococci) Carriage in Late Pregnancy in Kuwait

Al‐Sweih

Maiyegun²,

Diejomaoh³

et al. 2003

Med Princ Pract

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Objectives: This study investigated the vaginal colonization rate of Streptococcus agalactiae (group B streptococci, GBS) in an antenatal population in a maternity hospital. Subjects and Methods: Anal, vaginal and combined anal and vaginal specimens were obtained from 110 pregnant women (mean age 30.7 ± 5.5 years) at 35–37 weeks of gestation, using a commercially prepared culturette, and transported in 0.5 ml of Stuart’s transport medium. The specimens were then cultured in standard selective Todd-Hewitt broth medium, supplemented with gentamicin and nalidixic acid. After 36 h of incubation, the broth culture was subcultured onto sheep blood agar and incubated in 5% carbon dioxide for 18–24 h. Representative colonies morphologically resembling GBS were tested with latex agglutination kit. Each culture-positive woman was given ampicillin or piperacillin prophylactically and followed up through labour and postpartum. Detailed records of biodata, antecedent antenatal events and pregnancy outcome were reviewed. Results: The combined vaginal and anal specimens were positive for GBS in 18 (16.4%) women. Gestational age at delivery was 39.01 ± 1.79 weeks. The deliveries were uneventful and no neonate developed sepsis. Diabetes mellitus and pregnancy-induced hypertension/hypertension were detected antenatally in 16.6 and 11.5%, respectively. GBS carriage was not associated with adverse outcome of pregnancy. Conclusion: The colonization rate of GBS in pregnant women in Kuwait is high, and on the basis of the documented benefits of antenatal screening in Western countries, we recommend routine screening especially for our at-risk patients.

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Vaginal colonization with Group B beta-hemolytic streptococcus as a risk factor for post-cesarean section febrile morbidity

Cited by 53 publications

References 5 publications

Group B Streptococcus and Premature Rupture of Membranes and Preterm Delivery

Group B Streptococcus and Premature Rupture of Membranes and Preterm Delivery

Maternal Peripartum Complications Associated with Vaginal Group B Streptococci Colonization

<i>Streptococcus agalactiae</i> (Group B Streptococci) Carriage in Late Pregnancy in Kuwait

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