Valeur diagnostique de la lymphocytose du liquide d’ascite et du gradient albumine sérum ascite dans la tuberculose péritonéale en milieu africain

Mahassadi, K. A.; N’Dri-Yoman, Thérèse; Attia, Ahmed S.; Doffou, Stanislas; Bathaix, Mamert Fulgence Yao; Kissi, Y. H.; Touré, F.; Agbe, N.; Say, E.

doi:10.1007/s12157-008-0054-9

Cited by 2 publications

(6 citation statements)

References 17 publications

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“…However, our results demonstrated a low rate of cirrhotic patients in relation to SAAG ≥ 1.1 g/dl (only 37.2% of cirrhosis had a SAAG high) contrary to the articles evoked. Regarding peritoneal tuberculosis, our results were consistent with those of the literature that is to say all patients (100%) had a low SAAG < 1.1 g/dl [13] [15] [17] [19]. In our study, there was a positive correlation between post-hepatitic cirrhosis and a transudative ascites fluid, between peritoneal tuberculosis, ovarian tumor, and the exudative fluidity of ascites fluid according to literature data [17] [20].…”

Section: Discussionsupporting

confidence: 91%

“…These two parameters were far superior to lymphocytosis for the diagnosis of tuberculosis. These results were also reported by Mahassadi, who recommended combined tests (SAAG + liquid ascites + lymphocytosis) for the diagnosis of tuberculosis in the absence of confirmatory histological examination [13]. In this study SAAG was an excellent marker for the etiological diagnosis of ascites compared to ascites protein concentration as proved by some authors [17] [18] [19] [20].…”

Section: Discussionsupporting

confidence: 80%

“…For a cut-off value of −1.24 g/dl, the diagnostic performance of SAAG was better at 89% (Se = 96%, Sp = 86%). Mahassadi et al In a similar study conducted at the Yopougon University Hospital Center in 2008, had a diagnostic efficiency of 60% for a threshold of 0.87 g/dl of SAAG (Se = 96%, Sp = 42%) [13]. Considering a lower threshold, there was better diagnostic performance of SAAG in the diagnosis of peritoneal tuberculosis due to the factors of undernutrition and ascites fluid infection.…”

Section: Discussionmentioning

confidence: 96%

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Interest of SAAG in Etiological Diagnosis of Ascites in African Black

Baptiste¹,

Dramane²,

Stanislass³

et al. 2018

OJGas

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Purpose: To show the interest of the serum-ascites concentration gradient in albumin (SAAG) in the etiological diagnosis of ascites in African black. Materiel and Methods: This was a monocentric observational and analytical study performed on patients over 15 years old and hospitalized in the Hepato-Gastroenterology department of Cocody from January 1st, 2010 to March 31st, 2017 for ascites. The cytology and chemistry of the ascites fluid and the protidogram were performed. The main outcome measure was the prediction of portal hypertension (PHT) or non-portal hypertension related causes of ascites from SAAG. Results: The hospital prevalence of ascites was 11%. There were 82 women (46.9%) and 93 men (53.1%) with a sex ratio (M/F) of 1.1. SAAG was low in 68.6% of cases and high in 31.4% of cases. The most common etiologies were post-viral cirrhosis (74%), HCC (16.60%) and peritoneal tuberculosis (13.7%) respectively. In the case of high SAAG, 91% of ascites related to PHT were observed, but also 77.5% of a low SAAG corresponded to ascites related to PHT (p = 0.024) with Se = 35% Sp = 84% and accuracy = 44%. All patients with peritoneal tuberculosis had a SAAG low of less than 1.1 g/dl significantly (p = 0.002). SAAG had a diagnostic performance of 89% in peritoneal tuberculosis at the cutoff value of −1.24 g/dl (AUROC = 0.91, Se = 96%, Sp = 86%) while in post viral hepatitis cirrhosis at a threshold of 0.58 g/dl the diagnostic performance was 60% (AUROC = 0.69, Se = 53%, Sp = 79%). Conclusion: The simple technical SAAG, allowing to distinguish the ascites linked to the PHT and the ascites not bound to the PHT, can be used like a method of diagnosis of the etiologies of the ascites especially in the peritoneal tuberculosis in the African countries low income.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 96%

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Interest of SAAG in Etiological Diagnosis of Ascites in African Black

Baptiste¹,

Dramane²,

Stanislass³

et al. 2018

OJGas

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show abstract

“…The approach is complex, and the isolation of BK is difficult [ 1 ]. From a biological point of view, no test seems to be sufficiently effective for diagnosis [ 2 , 3 , 5 , 8 ]. The direct search for BK in fluids (pleural, peritoneal) is usually negative, as these fluids are not bacillary [ 1 , 3 , 5 ].…”

Section: Discussionmentioning

confidence: 99%

“…1 ) [ 9 ]. Culture, which allows the germ to be found in 80 % of cases, causes a delay in diagnosis and treatment (at least 3 weeks) [ 3 , 5 , 8 ]. In addition, it is very resource-intensive.…”

Section: Discussionmentioning

confidence: 99%