Validation and Estimation of Uncertainty for a Glucose Determination Method GOD-PAP Using a Multi-calibrator as Reference

Rascón-Careaga, Antonio; Corella-Madueño, María Alba Guadalupe; García-Rojas, A. M.; Souflé-Vásquez, S. Z.; García-Moroyoqui, M. T.; Córdoba-Beltrán, L. J.; Cáñez-Carrasco, María Guadalupe; García-Alegría, Alejandro Monserrat

doi:10.1007/s12647-021-00441-5

Cited by 5 publications

(4 citation statements)

References 31 publications

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“…A venous blood sample was taken after 8–12 h fasting under aseptic circumstances for biochemical analysis; for FBS measurement, 2 ml blood was collected in a grey-capped vacutainer containing fluoride and assessed using the GOD-PAP method. [ 41 ] 2 ml blood was taken in a simple red-capped vacutainer for TG quantification and determined using the GPO-TOPS method. [ 42 ]…”

Section: Procedures Usedmentioning

confidence: 99%

“…A single measurement was taken to the nearest 100 g. WC was measured in the horizontal plane, midway between the inferior margin of the ribs and the superior border of the iliac crest, with a trustworthy measuring inch tape. FBS was calculated using the GOD-PAP method[ 41 ] and TG using the GPO-TOPS technique on a BioSystems Diagnostics Pvt. Ltd. (BDPL) BTS350-Semi-Automatic Analyser.…”

Section: Procedures Usedmentioning

confidence: 99%

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Comparison of triglyceride/glucose index and related parameters with Indian Diabetes Risk Score assessment in non-diabetic individuals visiting primary healthcare centre—A community-based cross-sectional study

Ramalingam,

Kar,

Senthil

2024

Journal of Family Medicine and Primary Care

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Context: Diabetes mellitus is a chronic metabolic disorder and has reached epidemic proportions in developing countries like India. Aims: Our study aimed to identify relationship between triglyceride glucose (TyG) index and related parameters with Indian diabetes risk score in non-diabetic individuals. Settings and Design: An analytical cross-sectional study was conducted in community at a primary healthcare centre attached to a medical college for six months from April 2022 to October 2022 after getting approval from institute ethical committee. Methods and Material: We conducted a cross-sectional study at a primary healthcare centre attached to the medical college for six months duration with a sample size of 107, aged ≥18 years, which included apparently healthy individuals not diagnosed with any type of diabetes. Indian diabetes risk score (IDRS) scale was calculated along with anthropometric measurements and biochemical laboratory investigations like fasting triglyceride and fasting blood glucose. Results: Our study population included 53.3% male and 46.7% female; the mean age of male was 29.70 ± 12.26 and female was 34.28 ± 11.91. The mean TyG index for male and female was 8.48 ± 0.45 and 8.39 ± 0.52, respectively. 52.3% of our study population belonged to high-risk category, and 47.7% belonged to moderate-risk category. We also found positive correlation between TyG index and its related parameters and IDRS score. In linear regression between IDRS and TyG index, we found positive correlation, and in logistic regression showed for every 1 unit rise in age, there was 1.28 times increase in IDRS score (P < 0.001). TyG-WHtR was superior to other TyG-related parameters in identifying high IDRS score (P < 0.001). Conclusions: TyG index and its related parameters can be used as a predictor in identifying diabetes mellitus along with IDRS score assessment in low-cost clinical settings like primary healthcare centre.

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Section: Procedures Usedmentioning

confidence: 99%

Section: Procedures Usedmentioning

confidence: 99%

Comparison of triglyceride/glucose index and related parameters with Indian Diabetes Risk Score assessment in non-diabetic individuals visiting primary healthcare centre—A community-based cross-sectional study

Ramalingam,

Kar,

Senthil

2024

Journal of Family Medicine and Primary Care

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“…The intracardiac blood was used to measure the blood glucose level using the method (20). Readings were made using a spectrophotometer with a wavelength of 546 nm.…”

Section: Blood Glucose Assaymentioning

confidence: 99%

Sub-Chronic Low-Doses of Chlorpyrifos Exposure Alter Short Chain Fatty Acid Levels and Causes Insulin Resistance

Sakinah,

Mustika,

Wibisono

et al. 2023

Preprint

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Background Indonesia is an agricultural country which has more than 33 million workers in agriculture. Chlorpyrifos is an organophosphate pesticide that is extensively used in agriculture attributed to its broad application on crops. The primary route of human exposure to pesticide residues is through oral ingestion. The specific toxic effect of chlorpyrifos exposure appeared to be associated with dysbiosis, reduced short-chain fatty acid (SCFA), and the incidence of hyperglycemia depending on the dose and duration. This study aims to evaluate the impact of chlorpyrifos exposure on SCFA levels-induced insulin resistance. Methods Thirty Wistar rats were divided into five different time exposure groups [0 days (Control group), 7 days (P1), 14 days (P2), 28 days (P3), and 56 days (P4)]. Chlorpyrifos was given 5 mg/kg BW orally every day. Jejunum villi height was measured to observe the intestinal barrier tight junction, and SCFA was evaluated by GCMS methods. Fasting blood glucose and fasting insulin were measured to calculate Homeostasis Model Assessment for Insulin Resistance (HOMA-IR). Results Oral exposure of chlorpyrifos decreased jejunum villi height, total SCFA levels, and increased the fasting blood glucose, the fasting insulin and HOMA-IR levels. P4 group (day 56) was lower jejunum villi height, lower total SCFA level, higher fasting blood glucose, higher fasting insulin and higher HOMA-IR levels than the control group (day 0) at p < 0.05 using ANOVA. Conclusion Sub-chronic low-dose chlorpyrifos exposure (5 mg/kg daily for 56 days) in rats led to significant insulin resistance and reduced SCFA levels. The strong time-effect relationship suggests that negative impact increasing with time and become prominent by day 56. These findings can provide valuable insights to users/farmers regarding the potential limitations on the duration of daily exposure.

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“…The samples were collected on day 28; fasting blood glucose levels were then measured with a spectrophotometer UV-Vis (546 nm). 13 The HbA1c level in a blood sample was measured using column chromatography. For each sample, we used a separate column, and we subsequently collected the liquid that had been eluted from the column and contained the HbA1c.…”

Section: Measurementsmentioning

confidence: 99%

Evaluation of Clitoria ternatea L. Flower Extract in Preventing Complications of Diabetes Mellitus

2023

TJNPR

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Diabetes mellitus type 2 (DM), a chronic metabolic condition, is now more common than ever globally. 1 Over the past three decades, DM patients have doubled. 2 Hyperglycemia, insulin resistance, and relative insulin deficiency are the characteristics of this disease. 1 A previous study found a high prevalence of glucose intolerance and undiagnosed DM in the population, highlighting the need for regular screening to reduce its incidence and complications in the short and long term. 3 The HbA1c test accurately measures chronic glycemic levels and assesses the risk of DM complications. 4 According to studies, oxidative stress, evidenced by high levels of biomarkers like MDA, has a significant impact on the development and complications of DM by encouraging lipid peroxidation, protein oxidation, and oxidative DNA damage. 5 Therefore, prevention and management of DM are critical to achieving therapeutic targets and preventing complications. 6

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Validation and Estimation of Uncertainty for a Glucose Determination Method GOD-PAP Using a Multi-calibrator as Reference

Cited by 5 publications

References 31 publications

Comparison of triglyceride/glucose index and related parameters with Indian Diabetes Risk Score assessment in non-diabetic individuals visiting primary healthcare centre—A community-based cross-sectional study

Comparison of triglyceride/glucose index and related parameters with Indian Diabetes Risk Score assessment in non-diabetic individuals visiting primary healthcare centre—A community-based cross-sectional study

Sub-Chronic Low-Doses of Chlorpyrifos Exposure Alter Short Chain Fatty Acid Levels and Causes Insulin Resistance

Evaluation of Clitoria ternatea L. Flower Extract in Preventing Complications of Diabetes Mellitus

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