Validation of a disease‐specific quality‐of‐life instrument for acoustic neuroma

Shaffer, Brian T.; Cohen, Michael S.; Bigelow, Douglas C.; Ruckenstein, Michael J.

doi:10.1002/lary.20988

Cited by 116 publications

(158 citation statements)

References 20 publications

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“…Initial evaluation yielded robust face, content, criterion, and construct validity with high test-retest reliability. 30 The current study corroborates previous data demonstrating that the PANQOL is a more responsive instrument to disease-and treatment-associated changes than multipurpose measures such as the SF-36 or PROMIS-10. 30 Specifically, after multivariable adjustment, the latter 2 instruments did not demonstrate any statistically significant differences between patients receiving SRS, observation, or microsurgery.…”

Section: Discussionsupporting

confidence: 90%

“…30 The current study corroborates previous data demonstrating that the PANQOL is a more responsive instrument to disease-and treatment-associated changes than multipurpose measures such as the SF-36 or PROMIS-10. 30 Specifically, after multivariable adjustment, the latter 2 instruments did not demonstrate any statistically significant differences between patients receiving SRS, observation, or microsurgery. Moreover, in almost every case the SF-36 and PROMIS-10 failed to detect differences between nontumor controls and patients with VS, while the PANQOL did so in almost every subdomain score.…”

Section: Discussionsupporting

confidence: 90%

“…This questionnaire has been validated previously and was shown to discriminate VS patients from nontumor controls better than the SF-36. 30 The PANQOL consists of 26 questions with responses ranging from 1 to 5, with 1 denoting strong disagreement through 5 indicating strong agreement. Domain scores for facial function, balance, hearing, pain, anxiety, energy, and general health are obtained by averaging the responses of items assigned to the domain.…”

Section: Hrqol Assessmentmentioning

confidence: 99%

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Long-term quality of life in patients with vestibular schwannoma: an international multicenter cross-sectional study comparing microsurgery, stereotactic radiosurgery, observation, and nontumor controls

Carlson¹,

Tveiten²,

Driscoll

et al. 2015

JNS

185

178

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abbreviatioNs AAO-HNS = American Academy of Otolaryngology-Head and Neck Surgery; CPA = cerebellopontine angle; GBI = Glasgow Benefit Inventory; HRQOL = health-related quality of life; IQR = interquartile range; MCID = minimum clinically important difference; PANQOL = Penn Acoustic Neuroma Quality-of-Life; PROMIS-10 = 10-item Patient-Reported Outcomes Measurement Information System; SF-36 = 36-Item Short Form Health Survey; SRS = stereotactic radiosurgery; VS = vestibular schwannoma. submitted March 18, 2014. accepted November 11, 2014. iNclude wheN citiNg Published online January 2, 2015; DOI: 10.3171/2014.11.JNS14594. disclosure The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper. Internal departmental funding was used without commercial sponsorship or support. obJect The optimal treatment for sporadic vestibular schwannoma (VS) is highly controversial. To date, the majority of studies comparing treatment modalities have focused on a narrow scope of technical outcomes including facial function, hearing status, and tumor control. Very few publications have investigated health-related quality of life (HRQOL) differences between individual treatment groups, and none have used a disease-specific HRQOL instrument. methods All patients with sporadic small- to medium-sized VSs who underwent primary microsurgery, stereotactic radiosurgery (SRS), or observation between 1998 and 2008 were identified. Subjects were surveyed via postal questionnaire using the 36-Item Short Form Health Survey (SF-36), the 10-item Patient-Reported Outcomes Measurement Information System short form (PROMIS-10), the Glasgow Benefit Inventory (GBI), and the Penn Acoustic Neuroma Quality-of-Life (PANQOL) scale. Additionally, a pool of general population adults was surveyed, providing a nontumor control group for comparison. results A total of 642 respondents were analyzed. The overall response rate for patients with VS was 79%, and the mean time interval between treatment and survey was 7.7 years. Using multivariate regression, there were no statistically significant differences between management groups with respect to the PROMIS-10 physical or mental health dimensions, the SF-36 Physical or Mental Component Summary scores, or the PANQOL general, anxiety, hearing, or energy subdomains. Patients who underwent SRS or observation reported a better total PANQOL score and higher PANQOL facial, balance, and pain subdomain scores than the microsurgical cohort (p < 0.02). The differences in scores between the nontumor control group and patients with VS were greater than differences observed between individual treatment groups for the majority of measures. coNclusioNs The differences in HRQOL outcomes following SRS, observation, and microsurgery for VS are small. Notably, the diagnosis of VS rather than treatment strategy most significantly impacts quality of life. Understanding that a large number of VSs do not grow following discovery, and that intervention does not...

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 90%

Section: Hrqol Assessmentmentioning

confidence: 99%

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Long-term quality of life in patients with vestibular schwannoma: an international multicenter cross-sectional study comparing microsurgery, stereotactic radiosurgery, observation, and nontumor controls

Carlson¹,

Tveiten²,

Driscoll

et al. 2015

JNS

185

178

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“…Gruplar arasında fonksiyonlarda SF-36 yaşam kalitesi değerlendirme ölçeği ile anlamlı fark saptamamışlardır. Ayrıca bu çalışmada PANQOL yaşam kalitesi ölçeğinin de akustik nörinoma hastalarında kullanılabileceğini bildirmişlerdir (11). Bizim çalışmamızda hem sadece internal akustik kanalda yerleşim gösterenlerde hem de serebellopontin köşe ve internal akustik kanalda yerleşim gösterenlerde SF-36 yaşam kalitesi değerlendirme ölçeği ortalamasında ise en fazla canlılık skorunda düşme gözlendi.…”

Section: Resultsunclassified

Stereotakti̇k Radyoterapi̇ni̇n Akusti̇k Nöri̇noma Hastalari Üzeri̇ne Etki̇si̇

Bulğurcu¹,

Arslan²,

Uğur³

et al. 2016

Mustafa Kemal Üniversitesi Tıp Dergisi

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Amaç: Akustik nörinoma için tedavi seçenekleri, mikrocerrahi, stereotaktik radyoterapi ve her ikisinin birlikte kullanımıdır. Bu çalışmamızda, kliniğimizde akustik nörinoma nedenli stereotaktik radyoterapi uyguladığımız hastaların tedavi sonrası kitle boyutlarındaki, işitme düzeylerindeki değişimler ve yaşam kalitesi değerlendirildi.Gereç ve Yöntem: Eylül 2009 ile Mayıs 2016 tarihleri arasında kliniğimizde üç santimetreden küçük akustik nörinoma saptanmış 22 hasta retrospektif olarak değerlendirildi. Hastalara stereotaktik radyoterapi ile 12 Gray doz uygulandı. Magnetik rezonans ile tedavi öncesi ve sonrası boyutları ve odyogramda işitme düzeyleri ve konuşmayı ayırt etme skorları hesaplandı. Tedavi sonrası SF-36 Yaşam Kalitesi Değerlendirme Ölçeği ile yaşam kaliteleri değerlendirildi.Bulgular: Stereotaktik radyoterapinin hem sadece internal akustik kanalda yerleşim gösteren hem de serebellopontin köşe ve internal akustik kanalda birlikte yerleşim gösteren akustik nörinoma hastalarında işitme kaybına ve konuşmayı ayırt etme eşiği skorlarında düşmeye sebep olduğu ancak istatiksel olarak anlamlı olmadığı görüldü (P>0,05). Son kontrollerinde çekilen magnetik rezonansta 12'sinin akustik nörinoma boyutları stabil seyrederken, 2'sinde boyutlarda progresyon ve 8'inin boyutlarda regresyon izlendi. Yaşam Kalitesi Değerlendirme Ölçeği değerlendirme sonucunda en fazla canlılık skorlamasında düşme olduğu izlendi. Sonuç: Stereotaktik radyoterapi 3 santimetre altındaki akustik nörinoma tanısı almış hastalarda işitme fonksiyonu, kitle boyutlarındaki değişim ve yaşam kalitesinde düşük morbitideyle birlikte kullanılabilmektedir.

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“…A publication by Schaffer et al [32] validated a VS-specific QOL measurement tool named PANQOL, and that may be something researchers begin to use more moving forward. This study used a functional questionnaire that is very similar to one that was developed by the VS Association and one that has been used in previous research [8,33].…”

Section: Discussionmentioning

confidence: 99%

Gamma Knife Radiosurgery for Vestibular Schwannomas and Quality of Life Evaluation

Berkowitz

Han²,

Talbott³

et al. 2017

Stereotact Funct Neurosurg

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Background: Further investigation is needed to look at the impact of vestibular schwannoma (VS) on the health-related quality of life (QOL) of participants who undergo Gamma Knife® radiosurgery (GKRS). Objectives: Investigators compared the QOL for VS participants to reported US population norms in order to evaluate disease burden and long-term QOL several years after GKRS. Methods: This cross-sectional study surveyed participants to assess hearing status, tinnitus, imbalance, vertigo, as well as the Short-Form 36-item Health Questionnaire (SF-36). The data were normalized, age adjusted, and functional status was correlated to determine clinically significant differences. Results: A total of 353 participants who underwent GKRS between 1997 and 2007 were included in this study with a median postoperative period of 5 years. SF-36 scores were very similar to population norms, and age-adjusted scores for participants followed the US population curve. Frequent vertigo and balance problems had the largest statistically and clinically significant effect on physical and mental component summary scores followed by nonuseful hearing in the tumor ear. Conclusions: Participants reported a good long-term QOL that was very similar to the QOL of US population norms. Of the common VS symptoms, vertigo had the greatest impact on QOL followed by imbalance and then hearing loss.

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Validation of a disease‐specific quality‐of‐life instrument for acoustic neuroma

Cited by 116 publications

References 20 publications

Long-term quality of life in patients with vestibular schwannoma: an international multicenter cross-sectional study comparing microsurgery, stereotactic radiosurgery, observation, and nontumor controls

Long-term quality of life in patients with vestibular schwannoma: an international multicenter cross-sectional study comparing microsurgery, stereotactic radiosurgery, observation, and nontumor controls

Stereotakti̇k Radyoterapi̇ni̇n Akusti̇k Nöri̇noma Hastalari Üzeri̇ne Etki̇si̇

Gamma Knife Radiosurgery for Vestibular Schwannomas and Quality of Life Evaluation

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