Validation of a portable recording device (ApneaLink) for identifying patients with suspected obstructive sleep apnoea syndrome

Ng, Susanna S.S.; Chan, Tsai Hor; To, Ka–Fai; Ngai, Jenny; Tung, Alvin; Ko, Fanny W.S.; Hui, David S.

doi:10.1111/j.1445-5994.2008.01827.x

Cited by 132 publications

(124 citation statements)

References 24 publications

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“…Previous studies have one or more of the following limitations: (a) failure to study the PM device in its site of intended use, the home 18,19,27,28 ; (b) low sample size [16][17][18][19][20][21]27,28 ; (c) failure to collect oximetry data [16][17][18][19][20]27,29 ; (d) no randomization of order of comparison 18,19,27,28 ; and (d) no manual review of the raw PM data. [16][17][18][19][20]27,29,30 Our validation addresses these limitations.…”

Section: -11mentioning

confidence: 99%

A Comprehensive Evaluation of a Two-Channel Portable Monitor to “Rule in” Obstructive Sleep Apnea

Ward

McArdle

Bremner

et al. 2015

Journal of Clinical Sleep Medicine

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Study Objectives:We hypothesized that a dual-channel portable monitor (PM) device could accurately identify patients who have a high pretest probability of obstructive sleep apnea (OSA), and we evaluated factors that may contribute to variability between PM and polysomnography (PSG) results. Methods: Consecutive clinic patients (N = 104) with possible OSA completed a home PM study, a PM study simultaneous with laboratory PSG, and a second home PM study. Uniform data analysis methods were applied to both PM and PSG data. Primary outcomes of interest were the positive likelihood ratio (LR+) and sensitivity of the PM device to "rule-in" OSA, defi ned as an apnea-hypopnea index (AHI) ≥ 5 events/h on PSG. Effects of different test environment and study nights, and order of study and analysis methods (manual compared to automated) on PM diagnostic accuracy were assessed. Results: The PM has adequate LR+ (4.8), sensitivity (80%), and specifi city (83%) for detecting OSA in the unattended home setting when benchmarked against laboratory PSG, with better LR+ (> 5) and specifi city (100%) and unchanged sensitivity (80%) in the simultaneous laboratory comparison. There were no signifi cant night-night (all p > 0.10) or study order effects (home or laboratory fi rst, p = 0.08) on AHI measures. Manual PM data review improved case fi nding accuracy, although this was not statistically signifi cant (all p > 0.07). Misclassifi cation was more frequent where OSA was mild. Conclusions: Overall performance of the PM device is consistent with current recommended criteria for an "acceptable" device to confi dently "rule-in" OSA (AHI ≥ 5 events/h) in a high pretest probability clinic population. Our data support the utility of simple two-channel diagnostic devices to confi rm the diagnosis of OSA in the home environment.

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Section: -11mentioning

confidence: 99%

A Comprehensive Evaluation of a Two-Channel Portable Monitor to “Rule in” Obstructive Sleep Apnea

Ward

McArdle

Bremner

et al. 2015

Journal of Clinical Sleep Medicine

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“…The mean nocturnal SaO 2 (<SaO2>) and SaO 2 nadir were registered. Since ApneaLink does not differentiate between central or obstructive respiratory events, mild SDB was diagnosed in the presence of an ODI between 2 and 5 and severe SDB was defined by an ODI of ≥5 (15,16,18).…”

Section: Sleep Assessmentmentioning

confidence: 99%

“…Sleep assessment was performed using a portable device (ApneaLink, ResMed, Basel, Switzerland; refs [15][16][17], at baseline and after 4-6 months of therapy when SDB was observed during the first investigation. Respiratory airflow was measured by a nasal pressure cannula (detecting −10 hPa to +10 hPa) and oxygen saturation (SaO 2 ) and pulse rate were obtained by using a pulse oxymeter and a pulse sensor (sampling rate of 1 Hz).…”

Section: Sleep Assessmentmentioning

confidence: 99%

Weight Loss and Sleep‐Disordered Breathing in Childhood Obesity: Effects on Inflammation and Uric Acid

Hoorenbeeck

Franckx²,

Debode³

et al. 2012

Obesity

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Sleep‐disordered breathing (SDB) is prevalent in childhood obesity. It may be an independent risk factor for the metabolic syndrome. Possible mechanisms are inflammation and oxidative stress. Adenotonsillectomy in childhood obesity is associated with a high recurrence rate and risk of postoperative weight gain. Therefore, this study assessed the effects of SDB on inflammation and oxidative stress in childhood obesity before and after weight loss. We included 132 obese subjects between 10 and 18 years consecutively. Median age was 15.4 years (10.1–18.0). Mean BMI z‐score was 2.72 ± 0.42. Leukocytes and differentiation, high sensitivity C‐reactive protein (hs‐CRP), and uric acid (UA) were determined at baseline and subjects underwent a sleep assessment. SDB was diagnosed in 39%. Linear regression analysis showed an association between UAlog and oxygen desaturation indexlog (ODIlog) (r = 0.20; P = 0.03), between leukocyteslog and respiratory disturbance indexlog (RDIlog) (r = 0.23; P = 0.01), and between lymphocyteslog and RDIlog (r = 0.19; P = 0.04). Follow‐up was organized after 4–6 months of treatment. Median decrease in BMI z‐score was 32%. Laboratory measurements were repeated. Subjects with SDB at baseline underwent a second sleep study. Of these 49 subjects, 12 showed residual SDB. This corresponds with a treatment success rate of 71%. Unlike changes in inflammatory markers, improvements in UA were associated with improvements in RDI and ODI (respectively: r = 0.44; P = 0.007, r = 0.41; P = 0.01). In conclusion, weight loss is effective in treating obese children with SDB. At baseline, a link exists between inflammation and SDB. Oxidative stress is reflected by UA at baseline and the concentration decreases after treatment according to improvements in SDB.

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“…Данный аппарат валидирован для популяции больных с морбид-ным ожирением: чувствительность и специфичность ApneaLink по сравнению с полиграфией (Embletta) для ИАГ≥15 составляют 94 и 94% соответственно [8]. Коэффициент корреляции по Пирсону между ИАГ по дан-ным полисомнографии и ИАГ по данным ApneaLink составляет r = 0,978, p < 0,001 [9]. СиПАП-терапию реко-мендовали пациентам с ИАГ≥30, а также с ИАГ≥15 и при-знаками дневной сонливости (ESS≥10).…”

Section: диссертантunclassified

Cpap-Therapy Decreases Glycated Hemoglobin in Patients With Type 2 Diabetes Mellitus and Sleep Apnoea

Бурчаков¹,

Майоров²

2017

Med. sov.

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Validation of a portable recording device (ApneaLink) for identifying patients with suspected obstructive sleep apnoea syndrome

Abstract: Background: Polysomnography (PSG) is currently the standard diagnostic

Cited by 132 publications

References 24 publications

A Comprehensive Evaluation of a Two-Channel Portable Monitor to “Rule in” Obstructive Sleep Apnea

A Comprehensive Evaluation of a Two-Channel Portable Monitor to “Rule in” Obstructive Sleep Apnea

Weight Loss and Sleep‐Disordered Breathing in Childhood Obesity: Effects on Inflammation and Uric Acid

Cpap-Therapy Decreases Glycated Hemoglobin in Patients With Type 2 Diabetes Mellitus and Sleep Apnoea

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