Validation of the EQ-5D in Patients with Traumatic Limb Injury

Hung, Mei; Lu, Wen; Chen, Sheng Shiung; Hou, Wen Hsuan; Hsieh, Ching-Lin; Wang, Jung‐Der

doi:10.1007/s10926-014-9547-0

Cited by 55 publications

(32 citation statements)

References 25 publications

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“…However, we found that self-care, index scores, and VAS of EQ-5D-3L showed moderate correlations with the social relationship domain of the WHOQOL-BREF (r = −0.337, −0.307, −0.356, respectively). These findings are similar to previous studies showing that small—moderate correlation existed between the index score/VAS scores of EQ-5D social relationship domain (Hung et al 2015; Konig et al 2007). The findings were somewhat different from our hypotheses.…”

Section: Discussionsupporting

confidence: 92%

Reliability and validity of the EQ-5D-3L for Kashin–Beck disease in China

et al. 2016

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BackgroundKashin–Beck Disease (KBD) is an endemic osteoarthropathy in areas which extend from the North-East to the South-West of China. Most of the patients with KBD suffer multiple dysfunctions in major joints causing decreased health status. However because of their low education level and unique living habits, it is hard to find tools to measure the health-related quality of life (HRQOL). European quality of life (EQ-5D-3L) patient-reported instrument is widely used to measure HRQOL. This study aimed to establish the validity and reliability of the Chinese version of the EQ-5D-3L for evaluating HRQOL of KBD individuals in rural area.Methods368 individuals who were suffering from KBD were recruited through stratified multistage random sampling from Shaanxi province, China. The EQ-5D-3L and the WHOQOL-BREF were administrated in each individual by face to face interview. Test–retest reliability was assessed at 10–14 days intervals. The test–retest reliability was measured by calculating the Kappa coefficients for EQ-5D-3L five dimensions. For the EQ VAS, the intraclass correlation coefficient (ICC) was computed. Convergent and divergent analysis, construct validity was established using Spearman’s rank correlation between the EQ-5D-3L and the WHOQOL-BREF. Known groups’ validity was examined by comparing groups with a priori expected differences in health-related quality of life (HRQOL).ResultsFor 362 individuals (98%), comprehensive data of all the EQ-5D-3L dimensions were available. Kappa values of the EQ-5D-3L five items ranged from 0.324 to 0.554. ICC of the EQ VAS was 0.497. For convergent validity, the three items (self-care, usual activity, and mobility) of EQ-5D-3L, index scores, and VAS showed moderate correlations with the physical health domain of the WHOQOL-BREF (r absolute value ranged from 0.339 to 0.475). For divergent validity, the 5 items of EQ-5D-3L showed weak or no correlations with environment and social relationship domains of WHOQOL-BREF. The Chinese EQ-5D-3L clearly demarcated between groups which were reporting severe disease degree, poorer general health, more number of painful joints with worse HRQOL.ConclusionsThe EQ-5D-3L Chinese Version demonstrated fair to moderate levels of test–retest reliability and adequate construct validity in KBD individuals in China.

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Section: Discussionsupporting

confidence: 92%

Reliability and validity of the EQ-5D-3L for Kashin–Beck disease in China

et al. 2016

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“…One of the most used instruments in trauma care is the EQ-5D. The EQ-5D is a standardized generic measure of health-related quality of life whose validity, reliability, and responsiveness have been tested in studies for other extremity morbidities [24][25][26][27][28][29][30]. We have used the EQ-6D that is an extended version of the EQ-5D questionnaire and has an additional question addressing the cognitive function [29,30].…”

Section: Discussionmentioning

confidence: 99%

Association of pre-treatment radiographic characteristics of calcaneal fractures on patient-reported outcomes

Alexandridis

Gunning

Olden

et al. 2018

International Orthopaedics (SICOT)

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“…Our study revealed the patients with BE in Taiwan had poor HRQOL in physical domain but better in environment domain. WHOQOL-BREF is a sensitive tool to evaluate HRQOL for patients with different diseases, such as diabetes mellitus [39], tuberculosis [40], lung cancer [37], inflammatory bowel disease [41], irritable bowel syndrome [42, 43], morbid obesity [30, 35, 44], epilepsy [34], heroin-dependent patients [45] and traumatic limb injury [46]. It is not only useful to compare the difference of HRQOL between cases and controls [34, 35, 38, 42] or subgroups with different severity [35] but also serves as a standard index in validation study for other disease-specific questionnaire [39, 40, 44, 46].…”

Section: Discussionmentioning

confidence: 99%

Health-related quality of life in patients with Barrett’s esophagus

Chang

Lee

Wang

et al. 2016

Health Qual Life Outcomes

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BackgroundGastroesophageal reflux disease (GERD) has become a major health problem globally, affecting patients’ health-related quality of life (HRQOL). Barrett’s esophagus (BE) is a precancerous lesion associated with GERD. BE patients might not only suffer from HRQOL losses by GERD but also face psychological distress due to the increased risk of developing cancer. However, the majority of patients in Asia have shorter BE segment which is different from the West. This study aimed to determine whether the HRQOL in BE patients were worse than in healthy referents in Taiwan.MethodsPatients who received referral esophagogastroduodenoscopy for various symptoms were evaluated for the existence of BE. Lesions were judged as endoscopically suspected esophageal metaplasia (ESEM) if they showed morphological resemblances to BE by endoscopy. The diagnosis of BE was confirmed by histology with intestinal metaplasia or gastric metaplasia based on the Montreal definition. The World Health Organization Quality of Life (WHOQOL-BREF) was administered to BE patients before treatment. For each BE patient, we selected 2 age-, sex-, educational background and municipality-matched healthy referents, sampled by simple randomization method from a national survey in Taiwan. Multiple linear regression models were constructed to control the potential confounders.ResultsA total of 84 patients diagnosed with BE were enrolled as BE group and then compared with 168 healthy referents. The BE group had significantly lower WHOQOL-BREF scores than those of healthy referents in the physical domain (P < 0.05) but higher scores in the environment domain (P < 0.05). In the physical domain, the BE group had significantly lower scores in various facets, including pain, discomfort, sleep and rest and dependence on medications or treatments. There was no significant difference in social and psychological domains between the BE group and healthy referents.ConclusionsBE patients suffer from poor sleep and rest and high dependence on medications, which significantly reduce their quality of life. Individual facets of each domain warrants a better clinical healthcare to improve quality of life of BE patients.

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Validation of the EQ-5D in Patients with Traumatic Limb Injury

Abstract: The EQ-5D has sufficient construct validity, predictive validity, and responsiveness, and also provides evidence for using the utility of the EQ-5D for cost-utility analyses of patients with traumatic limb injuries in the future.

Cited by 55 publications

References 25 publications

Reliability and validity of the EQ-5D-3L for Kashin–Beck disease in China

Reliability and validity of the EQ-5D-3L for Kashin–Beck disease in China

Association of pre-treatment radiographic characteristics of calcaneal fractures on patient-reported outcomes

Health-related quality of life in patients with Barrett’s esophagus

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