Validation of the Generalized Anxiety Disorder-7 (GAD-7) in Russian people with epilepsy

Zinchuk, Mikhail; Kustov, Georgii; Pashnin, Evgenii; Gersamia, Anna; Rider, Flora; Yakovlev, A. A.; Voinova, Nadezhda; Popova, Sofya; Аведисова, А С; Guekht, Alla

doi:10.1016/j.yebeh.2021.108269

Cited by 20 publications

(9 citation statements)

References 42 publications

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“…The higher the total score, the more severe are the anxious symptoms. Previous studies showed that the cutoff scores ranged from >5 to >10 among different countries in epilepsy 27–29 . In our previous study, 7 points was verified as the optimal cutoff score, with a sensitivity of 94% and specificity of 91.4% 30 .…”

Section: Methodsmentioning

confidence: 62%

“…Previous studies showed that the cutoff scores ranged from >5 to >10 among different countries in epilepsy. [27][28][29] In our previous study, 7 points was verified as the optimal cutoff score, with a F I G U R E 1 Comparison of somatic symptoms and related disorders (SSD) characteristics between people with epilepsy without SSD and those with SSD. (A) Higher frequency of 25 somatic symptoms according to the bodily distress syndrome checklist (BDS checklist) in people with epilepsy with SSD.…”

Section: Generalized Anxiety Disorder Scalementioning

confidence: 99%

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Somatic symptoms and related disorders in a large cohort of people with epilepsy: A cohort study

et al. 2022

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Objective: This study was undertaken to characterize somatic symptoms and related disorders (SSD) in epilepsy. Methods: Adults with epilepsy under active follow-up at a tertiary epilepsy center were consecutively enrolled. The diagnosis of SSD was performed by an experienced psychologist based on the structured clinical interview for Statistical Manual of Mental Disorders, 5th edition. Detailed social/demographic data, epilepsy features, psychiatric features, life quality, disability, and economic burden were collected and compared between people with SSD and those without. Bodily distress syndrome checklist, Somatic Symptom Disorder-B Criteria Scale, Patient Health Questionnaire-9, and Generalized Anxiety Disorder seven-item scale (GAD-7) were used to evaluate SSD individuals' somatic symptoms, symptomrelated psychological distress, and depressive and anxious symptoms. Quality of life and disability were assessed by Quality of Life in Epilepsy Inventory 31 (QOLIE-31) and World Health Organization Disability Assessment Schedule V.2.0 (WHO DAS 2.0). A risk prediction nomogram was generated using least absolute shrinkage and selection operator (LASSO) analysis and validated.Results: One hundred fifty of 631 participants (24%) were diagnosed with SSD.In people with SSD, the top three most common somatic symptoms were memory impairment, headache, and dizziness (85%, 80%, and 78%, respectively), and multiple systems were involved in most (82%) people with SSD. Compared with people without SSD, those with SSD had lower QOLIE-31 total scores, and higher WHO DAS 2.0 scores and disease economic burdens. LASSO analysis suggested that a history of severe traumatic brain injury, hippocampal sclerosis, low seizure worry and medication effects scores on QOLIE-31, multiple systems affected by somatic symptoms, and a high GAD-7 score were risk factors of SSD. The nomogram was validated for good accuracy in the training and testing cohorts.Significance: SSD are likely to be a common comorbidity in epilepsy and harm epilepsy prognosis. Our risk prediction nomogram was successfully developed but needs further validation in larger cohorts.

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Section: Methodsmentioning

confidence: 62%

Section: Generalized Anxiety Disorder Scalementioning

confidence: 99%

Somatic symptoms and related disorders in a large cohort of people with epilepsy: A cohort study

et al. 2022

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“…A free version can be downloaded at the ILAE's homepage. It has been validated for the use in PWE and is available in different translations: Chinese ( 48 ), French ( 49 ), Indonesian ( 50 ), Korean ( 51 ), Russian ( 52 ). The availability in multiple languages allows to perform cross-cultural comparisons in different populations.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Anxiety in Patients With Epilepsy: A Literature Review

2022

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ObjectiveApproximately 20% of people with epilepsy (PWE) suffer from anxiety. These fears are quite diverse and may manifest periictally or interictally, be part of the seizure's semiology, or an expression of reactive psychological distress from seizures themselves. Our review addresses the question of what screening tools are used in clinical care and epileptological research to capture the complexity of epilepsy-specific anxieties.MethodOn 2021/11/11, we entered a search string in PubMed that covered our research interest as completely as possible. We also screened the bibliographies of our findings and followed PubMed's recommendations. From the assessments we found in the included studies, we extracted domains that represent the range of manifestations of anxiety, in order to compare the tools and to discuss to what extent they are suitable for assessing epilepsy-specific anxieties.ResultsWe screened 1,621 abstracts. In total, we identified 24 different anxiety assessments. In addition to the psychiatric assessments in use, we found 7 tools that were designed to assess epilepsy-specific anxieties. The latter focus on different aspects of epilepsy-specific anxieties. In some cases, the conceptual frameworks are not sufficiently transparent or divergent.ConclusionBecause a diagnosis of epilepsy can result in, or seizures may appear as, anxiety, it is important to better understand this psychological burden and address it therapeutically, if necessary. There is a need for screening tools that integrate specific points of a variety of assessments, so as to cover the broad range of epilepsy-specific fears. None of the assessments we found meets this integrative perspective. At the same time, the appropriate design of such a required tool presupposes a conceptual framework of what should be considered as epilepsy-specific anxiety.

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“…Anxiety disorders in workers are linked to psychosocial factors at work ( 6 ), such as poor protection strategies, a lack of social support ( 7 ), and the uncertainty of the future job ( 8 ), and labor demands related to expected work efficiency (( 9 , 10 )). These requirements might be defined by single or several components of the job, such as precision, speed, and the ability to complete difficult tasks ( 11 ).…”

Section: Introductionmentioning

confidence: 99%

Psychometric properties of the generalized anxiety disorder-7 (GAD-7) in a sample of workers

Merino-Soto

Angulo-Ramos²,

Rovira-Millán

et al. 2023

Front. Psychiatry

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ObjectiveTo evaluate the psychometric properties of the GAD-7 by obtaining evidence of internal structure (dimensionality, precision and differential functioning of items) and association with external variables.MethodsA total of 2,219 protocols from three different studies conducted with Puerto Rican employees that administered the GAD-7 were selected for the current study. Item response theory modeling was used to assess internal structure, and linear association with external variables.ResultsThe items were adapted to a graduated response model, with high similarity in the discrimination and location parameters, as well as in the precision at the level of the items and in the total score. No violation of local independence and differential item functioning was detected. The association with convergent (work-related rumination) and divergent (work engagement, sex, and age) variables were theoretically consistent.ConclusionThe GAD-7 is a psychometrically robust tool for detecting individual variability in symptoms of anxiety in workers.

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Validation of the Generalized Anxiety Disorder-7 (GAD-7) in Russian people with epilepsy

Cited by 20 publications

References 42 publications

Somatic symptoms and related disorders in a large cohort of people with epilepsy: A cohort study

Somatic symptoms and related disorders in a large cohort of people with epilepsy: A cohort study

Assessment of Anxiety in Patients With Epilepsy: A Literature Review

Psychometric properties of the generalized anxiety disorder-7 (GAD-7) in a sample of workers

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