Valorization of Fish Processing By-Products: Microstructural, Rheological, Functional, and Properties of Silver Carp Skin Type I Collagen

Abstract

The objective of this study was to develop aquatic collagen production from fish processing by-product skin as a possible alternative to terrestrial sources. Silver carp skin collagen (SCSC) was isolated and identified as type I collagen, and LC-MS/MS analysis confirmed the SCSC as Hypophthalmichthys molitrix type I collagen, where the yield of SCSC was 40.35 ± 0.63% (dry basis weight). The thermal denaturation temperature (Td) value of SCSC was 30.37 °C, which was superior to the collagen of deep-sea fish and freshwater fish. Notably, SCSC had higher thermal stability than human placental collagen, and the rheological experiments showed that the SCSC was a shear-thinning pseudoplastic fluid. Moreover, SCSC was functionally superior to some other collagens from terrestrial sources, such as sheep, chicken cartilage, and pig skin collagen. Additionally, SCSC could provide a suitable environment for MC3T3-E1 cell growth and maintain normal cellular morphology. These results indicated that SCSC could be used for further applications in food, cosmetics, and biomedical fields.

Evaluation of the biocompatibility of fish skin collagen with the mesenchymal stem cells in in vitro cultures

“…Given its relatively high thermal stability, silver carp skin collagen is an attractive alternative for the food and pharmaceutical industries. 37,38 Furthermore, some literature sources reported the suitability of African sharptooth catfish collagen in the acceleration of wound healing, and as a scaffold for tissue engineering. 39,40…”

“…Given its relatively high thermal stability, silver carp skin collagen is an attractive alternative for the food and pharmaceutical industries. 37,38 Furthermore, some literature sources reported the suitability of African sharptooth catfish collagen in the acceleration of wound healing, and as a scaffold for tissue engineering. 39,40 The results of our research imply that collagen extracted from African sharptooth catfish and silver carp skins is biocompatible, in terms of ASCs growth, clonogenic potential, and differentiation in osteogenic and adipogenic lineages.…”

Exploring the Potential of Using Marine-Derived Ingredients: From the Extraction to Cutting-Edge Cosmetics

“…Guan et al [103] studied the cosmeceutical properties of silver carp skin collagen (SCSC). They found that SCSC exhibited excellent foaming and emulsifying properties, along with a superior water absorption capacity and oil absorption capacity when compared to proteins sourced from terrestrial origins.…”

A Thermostable Type I Collagen from Swim Bladder of Silver Carp (Hypophthalmichthys molitrix)

“…Generally, fish collagen is extracted from fish scales, skin or bones [ 8 ]. However, fish scales contain more calcium impurities, and fish skin has a high pigment content and a low thermal denaturation temperature [ 9 ], which limits their biomedical application. The main components of the swim bladder are collagen, elastin and polysaccharides.…”