Value of chest radiography in a tuberculosis prevention programme for HIV-infected people, Botswana

Mosimaneotsile, Barudi; Ea, Talbot; Tl, Moeti; Nm, Hone; Moalosi, G.; Hj, Moffat; Ej, Lee; Kenyon, T A

doi:10.1016/s0140-6736(03)14745-9

Cited by 52 publications

(43 citation statements)

References 2 publications

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“…Our data show that chest radiography facilitates prompt tuberculosis treatment initiation. Although implementation of chest radiography can be challenging, 29,30 we suggest it should be done where possible. In high prevalence settings systematic sputum culture for all patients prior to ART has also been suggested, but presents the same challenges of access.…”

Section: Discussionmentioning

confidence: 99%

Tuberculosis among adults starting antiretroviral therapy in South Africa: the need for routine case finding

Hanifa

Fielding²,

Charalambous³

et al. 2012

int j tuberc lung dis

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Section: Discussionmentioning

confidence: 99%

Tuberculosis among adults starting antiretroviral therapy in South Africa: the need for routine case finding

Hanifa

Fielding²,

Charalambous³

et al. 2012

int j tuberc lung dis

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“…Concerns about the ability to rule out active tuberculosis before starting preventive therapy, adherence with treatment, drug toxicity, and the development of isoniazid resistance have all contributed to low enthusiasm for IPT. Several studies have shown, however, that active tuberculosis can be excluded using relatively simple screening measures [34,35], and there is little evidence that IPT results in the emergence of drug resistance [36]. Although there has been a great and understandable interest in expanding the use of ART, which clearly has benefits beyond the prevention of tuberculosis, IPT has been relatively ignored.…”

Section: Discussionmentioning

confidence: 99%

The impact of antiretroviral therapy and isoniazid preventive therapy on tuberculosis incidence in HIV-infected patients in Rio de Janeiro, Brazil

Golub¹,

Saraceni²,

Cavalcante

et al. 2007

Aids

273

214

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“…The role of screening by chest radiography is controversial. Some studies show value and others do not, [58][59][60] and radiography is often unavailable in primary care.…”

Section: Intensifi Ed Case Fi Nding In Health Facilitiesmentioning

confidence: 99%

The HIV-associated tuberculosis epidemic—when will we act?

et al. 2010

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Journal LancetRights Reproduced on this site with permission of Elsevier Ltd. Please see [url] Tuberculosis 3The HIV-associated tuberculosis epidemic-when will we act? Anthony D Harries, Rony Zachariah, Elizabeth L Corbett, Stephen D Lawn, Ezio T Santos-Filho, Rhehab Chimzizi, Mark Harrington, Dermot Maher, Brian G Williams, Kevin M De Cock Despite policies, strategies, and guidelines, the epidemic of HIV-associated tuberculosis continues to rage, particularly in southern Africa. We focus our attention on the regions with the greatest burden of disease, especially sub-Saharan Africa, and concentrate on prevention of tuberculosis in people with HIV infection, a challenge that has been greatly neglected. We argue for a much more aggressive approach to early diagnosis and treatment of HIV infection in aff ected communities, and propose urgent assessment of frequent testing for HIV and early start of antiretroviral treatment (ART). This approach should result in short-term and long-term declines in tuberculosis incidence through individual immune reconstitution and reduced HIV transmission. Implementation of the 3Is policy (intensifi ed tuberculosis case fi nding, infection control, and isoniazid preventive therapy) for prevention of HIV-associated tuberculosis, combined with earlier start of ART, will reduce the burden of tuberculosis in people with HIV infection and provide a safe clinical environment for delivery of ART. Some progress is being made in provision of HIV care to HIV-infected patients with tuberculosis, but too few receive co-trimoxazole prophylaxis and ART. We make practical recommendations about how to improve this situation. Early HIV diagnosis and treatment, the 3Is, and a comprehensive package of HIV care, in association with directly observed therapy, short-course (DOTS) for tuberculosis, form the basis of prevention and control of HIV-associated tuberculosis. This call to action recommends that both HIV and tuberculosis programmes exhort implementation of strategies that are known to be eff ective, and test innovative strategies that could work. The continuing HIV-associated tuberculosis epidemic needs bold but responsible action, without which the future will simply mirror the past.

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Value of chest radiography in a tuberculosis prevention programme for HIV-infected people, Botswana

Cited by 52 publications

References 2 publications

Tuberculosis among adults starting antiretroviral therapy in South Africa: the need for routine case finding

Tuberculosis among adults starting antiretroviral therapy in South Africa: the need for routine case finding

The impact of antiretroviral therapy and isoniazid preventive therapy on tuberculosis incidence in HIV-infected patients in Rio de Janeiro, Brazil

The HIV-associated tuberculosis epidemic—when will we act?

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