Value of Fine-Needle Aspiration Cytology in the Evaluation of Parotid Tumors

Javadi, Morteza; Asghari, Alimohamad; Hassannia, Fatemeh

doi:10.1007/s12070-011-0297-4

Cited by 16 publications

(14 citation statements)

References 15 publications

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“… Diagnosing lymphoma is very difficult , among pathologist experiences. [13][14][15][16][17][18][19][20][21] Good collaboration between the otorhinolaryngologist and the pathologist provides the best results. However, in the context of a non-diagnostic FNAB, high suspicion for parotid malignancy may be warranted for otorhinolaryngologist.…”

Section: Discussionmentioning

confidence: 99%

“…However, in the context of a non-diagnostic FNAB, high suspicion for parotid malignancy may be warranted for otorhinolaryngologist. [19][20][21][22] FNAB under ultrasound guidance has higher sensitivity more than blind FNAB. Bajaj et al and Pratap et al reported that the sensitivity of FNAB was increased by 20% from to 65% to 85%, respectively, with using ultrasound guidance.…”

Section: Discussionmentioning

confidence: 99%

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Diagnostic value of fine needle aspiration biopsy in parotid gland neoplasm

Yeğin

Çelik

Olgun

et al. 2016

Int J Otorhinolaryngol Head Neck Surg

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Background: The value of fine needle aspiration biopsy (FNAB) in the diagnosis of parotid masses remains unclear, considering current literature. The surgical procedure is not planned according to the FNAB results by the majority of the otorhinolaryngologists. Objectives of the study was to compare the results of FNAB and histopathological results in diagnosing malignancy and benign lesions of parotid gland and to determine the sensitivity, specificity and accuracy of FNAB.Methods: It is a retrospective clinical chart review study. In total, 61 patients (28 females and 33 males; average age, 46.31±15.79 years; age range: 12-82 years) with parotid gland masses who underwent preoperative FNAB were included in this study. All patients underwent FNAB under ultrasound guidance following clinical examination. Histopathological results of the surgical specimens and preoperative results of FNAB were compared and, the sensitivity, specify, positive predictive value (PPV), negative predictive value (NPV), the diagnostic accuracy of FNAB was calculated. A P-value <0.05 was considered to reflect statistical significance. Results: The specificity of FNAB was 100% and its sensitivity was 57.2%. Accuracy for benign lesion was 91.4%, accuracy for a malignancy was 42.8% and overall diagnostic accuracy was 92.0%, respectively. PPV for benign lesion was 91.4% and the NPV was 100%, respectively. PPV for malignancy was 100% and the NPV was 91.4%, respectively.Conclusions: We suggest that FNAB is a valid, safe, easy-to-use method for identifying of parotid gland neoplasms. We recommend FNAB for all potential surgical patients. In our opinion, good collaboration between the Otorhinolaryngologist and the pathologist provides the best results.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Diagnostic value of fine needle aspiration biopsy in parotid gland neoplasm

Yeğin

Çelik

Olgun

et al. 2016

Int J Otorhinolaryngol Head Neck Surg

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“…27 The most important reasons leading to misdiagnosis and false negatives are lack of necessary expertise, presence of atypical cells in both benign and malignant lesions, association of chronic sialadenitis with several types of malignancy, and difficulty in diagnosing lymphoma. 28 Diagnostic dilemma has been reported in cases where mucoepidermoid carcinoma and/or Warthin's tumor present as cystic swellings, aspiration reveals inflammation instead of pleomorphic adenoma, adenoid cystic carcinoma is misinterpreted as pleomorphic adenoma or basal cell adenoma on aspiration cytology, and Warthin's tumor is cytodiagnosed as squamous cell carcinoma. 25 There are various lesions in the oral cavity, floor of mouth, tongue, palate, tonsils, and posterior pharyngeal wall that can be assessed by needle under visual control; however, little data have been published regarding usefulness of FNAC in the diagnosis of intraoral lesions.…”

Section: Discussionmentioning

confidence: 99%

Distributive Analysis of Head and Neck Swellings with Their Cytopathological Correlation

Singh¹,

Bhardwaj²,

Pandey³

2016

An International Journal of Otorhinolaryngology Clinics

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Aim: Palpable masses in the head and neck region can arise from various structures, such as lymph node, thyroid gland, major and minor salivary glands, soft tissues, blood vessels, and neural structures. Fine needle aspiration cytology (FNAC) is a simple, quick, inexpensive first-line method to evaluate such swellings and thus confirm the diagnosis. This study correlates aspiration cytology as an indispensable tool in diagnosing various head and neck swellings and their prevalence with respect to age, sex, site of origin, and nature of those masses. Materials and methods:This study was done from January 2007 to December 2013 in the Department of Otorhinolaryngology and Department of Pathology. All the patients presenting with various head and neck swellings underwent FNAC, and the results were correlated with anatomical sites and frequency of occurrence and categorized into various clinicopathological groups.Results: This study included 1,272 cases who were evaluated by FNAC for head and neck swellings. In this study, 32 patients presented with frank abscesses, 36 cases with submandibular region swellings, seven cases with submental swellings, 70 cases with various swellings in the neck and postauricular area, 47 cases with various facial and scalp swellings, two cases from oral cavity, 74 cases with parotid masses, 680 cases with lymphadenopathy, and 324 cases with thyroid lesions. Conclusion:Fine needle aspiration cytology is a useful, reliable, cost-effective, and valuable diagnostic tool for the initial evaluation and diagnostic categorization of all superficial and deep-seated lesions in the head and neck region as it is a fairly sensitive and specific procedure in addition to being simple, rapid, accurate, and without any significant complications and above all without affecting the underlying tissue morphology altogether.

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“…This is reinforced with the PPV of a ‘neoplastic’ FNAC result being 100% compared with the PPV for a benign FNAC result being only 86%. Previous studies have also reported a low sensitivity for malignancy but high specificity …”

Section: Discussionmentioning

confidence: 93%

“…Previous studies have also reported a low sensitivity for malignancy but high specificity. 6,7,11,12 There is limited literature comparing the efficacy of FNAC with imaging studies to identify parotid neoplasms and most published data focuses on the ability of specific imaging modalities to identify malignant parotid tumours. In comparing the results of this study to recent literature, FNAC showed lower sensitivity to computed tomography (CT) in identifying malignant lesions, 75 versus 100%, but greater specificity, 97.5 versus 42%.…”

Section: Discussionmentioning

confidence: 99%