2022
DOI: 10.1186/s12890-022-02234-1
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Value of sputum Gram stain, sputum culture, and bronchoalveolar lavage fluid Gram stain in predicting single bacterial pathogen among children with community-acquired pneumonia

Abstract: Background Currently, the microbial etiology of community-acquired pneumonia in children remains challenging. While Gram stain and sputum culture are commonly used to detect bacterial pathogens, it is unclear whether these approaches can predict single pathogen from bronchoalveolar lavage fluid (BALF) culture. Methods A retrospective study involving 287 children hospitalized for pneumonia was conducted. Sputum specimens were collected on admission;… Show more

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Cited by 6 publications
(7 citation statements)
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“…During the initial evaluation, aerobic blood cultures should be collected. It may be helpful if the patient is able to produce an adequate sputum sample (spontaneous or induced), although it is often not feasible in the pediatric population ( 14 ). In newly intubated patients, endotracheal aspirate should be collected if possible ( 14 ).…”
Section: Non-invasive Testingmentioning
confidence: 99%
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“…During the initial evaluation, aerobic blood cultures should be collected. It may be helpful if the patient is able to produce an adequate sputum sample (spontaneous or induced), although it is often not feasible in the pediatric population ( 14 ). In newly intubated patients, endotracheal aspirate should be collected if possible ( 14 ).…”
Section: Non-invasive Testingmentioning
confidence: 99%
“…It may be helpful if the patient is able to produce an adequate sputum sample (spontaneous or induced), although it is often not feasible in the pediatric population ( 14 ). In newly intubated patients, endotracheal aspirate should be collected if possible ( 14 ). Concurrently, all patients should undergo respiratory viral testing with PCR, complemented with serum evaluation where feasible, focusing on CMV and adenovirus.…”
Section: Non-invasive Testingmentioning
confidence: 99%
See 1 more Smart Citation
“…Although it is the first step in in-hospital analysis, its sensitivity, reliability and impact on treatment decisions within various pathogens have been debated [4][5][6]. In addition to being difficult to obtain in subsets of patients and time consuming, sputum specimens are frequently contaminated with upper respiratory tract micro-organisms, leading to inconclusive results [7,8].…”
Section: Introductionmentioning
confidence: 99%
“…Multiple samples were used to detect the pathogens, whereas BALF is the ideal specimen for detecting the causative pathogen apart from lung tissue or aspirate. 5 A. baumannii is a Gram negative opportunistic human pathogen, which could cause a wide spectrum of illness including bloodstream infection, pneumonia, and endocarditis. 6 It has a remarkable capacity to develop antimicrobial resistance, and multidrug resistant strains may account for ∼45% of all isolates, which made them a serious health threat.…”
mentioning
confidence: 99%