Valve-based comprehensive two-dimensional gas chromatography with quadrupole mass spectrometry detection using a porous layer open tubular column in the first dimension

Mikaliunaite, Lina; Trinklein, Timothy J.; Ochoa, Grant S.; Sudol, Paige E.; Bell, David S.; Synovec, Robert E.

doi:10.1016/j.jcoa.2022.100076

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Developments In Gc × Gc Detection1

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2024

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“…When a scan is taken on the slope of the peak, the concentration of the analyte will vary, resulting in distorted and varying spectra. Rapid-scanning Q-MS systems have become available, but they are only occasionally used in contemporary GC × GC-MS practice [111][112][113][114][115]. Triple-quadrupole (QqQ) instruments have been demonstrated for online use with GC × GC [116][117][118].…”

Section: Developments In Gc × Gc Detectionmentioning

confidence: 99%

Comprehensive two‐dimensional gas chromatography— A discussion on recent innovations

Milani,

van Gilst,

Pirok

et al. 2023

J of Separation Science

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Although comprehensive 2‐D GC is an established and often applied analytical method, the field is still highly dynamic thanks to a remarkable number of innovations. In this review, we discuss a number of recent developments in comprehensive 2‐D GC technology. A variety of modulation methods are still being actively investigated and many exciting improvements are discussed in this review. We also review interesting developments in detection methods, retention modeling, and data analysis.

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