Valve Replacement in the Recanalized Incompetent Superficial Femoral Vein in Dogs

McLachlin, A. D.; Carroll, S E; Meads, G E; Amacher, A L

doi:10.1097/00000658-196509000-00014

Cited by 39 publications

(12 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At the present time more steps are still necessary for the percutaneous artificial venous valve implantation to become clinically useful. Some investigators [19][20][21][22][25][26][27][28] did not continue their research, nor did any other investigator pursue their techniques. The BVV3 stent frame is, in our opinion, well suited to form a base for a bioprosthetic venous valve.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous management of chronic deep venous reflux: review of experimental work and early clinical experience with bioprosthetic valve

et al. 2008

View full text Add to dashboard Cite

Lower extremity chronic deep venous insufficiency (CDVI) is common and remains a major health problem worldwide. Selected patients benefited from direct deep vein valve surgical repair or valve transplantation. A major limitation of this approach is that most of the patients are not candidates for these procedures due to obstructions or residual thrombus throughout the vein. The past 15 years have witnessed experimental efforts at catheter-based management of CDVI. This review describes the initial designs and experimental evolution of a mechanical and bioprosthetic venous valve that can be implanted by using a transcatheter technique. These valves consisted of single, double, or triple cusp leaflets made of synthetic or biological materials attached to a carrier or frame. All described devices for percutaneous transcatheter valve placement rely on some form of a vascular stent for valve attachment.

show abstract

Section: Discussionmentioning

confidence: 99%

Percutaneous management of chronic deep venous reflux: review of experimental work and early clinical experience with bioprosthetic valve

et al. 2008

View full text Add to dashboard Cite

show abstract

“…Transplantation of fresh canine allograft with no concern about rejection issues has been attempted in the past decades. In 1965, McLachlin et al 32 tested 14 fresh allografts in dogs with an initial 24 hours of full systemic anticoagulation. Of the 14 transplants, only 1 (7%) was patent and none was competent after a 4-week study period.…”

Section: Prosthetic Venous Valvesmentioning

confidence: 99%

Historical Overview of Venous Valve Prostheses for the Treatment of Deep Venous Valve Insufficiency

Zervides¹,

Giannoukas²

2012

Journal of Endovascular Therapy

View full text Add to dashboard Cite

Almost 3% of people in the Western world will suffer from a venous disease at some time in their lives, but as yet there are very few effective treatments for the venous system. When the valves become incompetent, they allow backflow and subsequent pooling of blood in the lower extremities. Current clinical therapies for the elimination of deep reflux are very invasive and provide short-lasting results. Thus, there is an urgent need for technological evolution of implantable valves and, if possible, with minimally invasive techniques. This review provides a basic history of the discovery of deep vein valves and various designs of prosthetic vein valves that have been evaluated in animal models and clinical studies.

show abstract

“…Transplantation of a valve containing vein from one dog as a fresh allograft to another while ignoring rejection issues resulted in failure. 17 Glutaraldehyde preserved allografts even when supported by a continually functioning dAVF but became incompetent in short order. 25 The umbilical vein can be frozen, cleaned, and then fitted over an aluminum mandrel and fixed with glutaraldehyde to sculpture it into a bicuspid valve.…”

Section: Venous Valve Substitutesmentioning

confidence: 99%

“…The isolated segment was filled with blood, bulldog clamps are applied above and below the area of trauma, and the dogs were reoperated in 2-4 days to remove the bulldog clamps. 15,17 Recanalization generally resulted in an acceptable model for venous valve transplantation (Table I). The addition of 24 hours of perioperative systemic heparinization to the venous valve transplantation improved the primary patency rate to ∼85% with a reported valve competency rate of ∼70%.…”

Section: Insufficiency Modelsmentioning

confidence: 99%

Animal Models for the Study of Lower Extremity Chronic Venous Disease: Lessons Learned and Future Needs

Dalsing

Ricotta

Wakefield

et al. 1998

Annals of Vascular Surgery

View full text Add to dashboard Cite

The purpose of this review is to define animal models of chronic venous disease and to demonstrate how animal studies can impact our understanding and treatment of this disorder. To this end an extensive literature search was conducted highlighting potential animal models of chronic lower extremity venous disease. Scientific investigations using animals to study particular aspects of this disease are also reviewed. This review was conducted by members of the Committee on Research of the American Venous Forum to help provide direction for future venous research endeavors. Useful models of chronic venous occlusive disease involve controlled ligation of a major lower limb vein and multiple tributaries. Such a model can provide sustained venous hypertension and studies using this model have confirmed that an isodiametric graft can provide early hemodynamic relief. Models of primary, postphlebitic, and isolated chronic deep venous insufficiency are available for study. Valve repair or transplantation can positively impact the insufficiency observed in these models. Investigations into valve substitutes have generally been disappointing or are undergoing early evaluation. In conclusion, animal models for the study of some aspects of chronic venous disease do exist and have already affected our clinical approach to patients. The scientific study of basic pathophysiology, diagnostics, end-organ response, and long-term surgical treatments of this disorder in well-controlled animal experiments have not been conducted.

show abstract

Valve Replacement in the Recanalized Incompetent Superficial Femoral Vein in Dogs

Cited by 39 publications

References 8 publications

Percutaneous management of chronic deep venous reflux: review of experimental work and early clinical experience with bioprosthetic valve

Percutaneous management of chronic deep venous reflux: review of experimental work and early clinical experience with bioprosthetic valve

Historical Overview of Venous Valve Prostheses for the Treatment of Deep Venous Valve Insufficiency

Animal Models for the Study of Lower Extremity Chronic Venous Disease: Lessons Learned and Future Needs

Contact Info

Product

Resources

About