“Vanishing Bone Disease” in Maxillofacial Region: A Review and Our Experience

Gulati, Ujjwal; Mohanty, Sujata; Dabas, Jitender; Chandra, Nidhee

doi:10.1007/s12663-015-0746-9

Cited by 11 publications

(11 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, after surgical intervention, primary reconstruction should be delayed until dormancy of the disease and arrest of osteolysis is confirmed. [ 9 10 ]…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Dilemma of Vanishing Bone Disease - A Case Report and Review of Literature

Saxena

Gopalakrishnan

Rangarajan

et al. 2023

Annals of Maxillofacial Surgery

View full text Add to dashboard Cite

Rationale: Vanishing bone disease (VBD) is a rare bone disorder in which progressive osteolysis may lead to complete disappearance of involved bones. The diagnosis of this disease requires a high degree of clinical suspicion. We present a case of progressive osteolysis of mandible in a patient. Patient Concerns: The patient had been without definitive diagnosis and treatment for over a year. Diagnosis: Diagnosis was made by exclusion of genetic, traumatic, inflammatory, infective, endocrine and neoplastic aetiologies and by carefully correlating clinical, imaging and histopathological findings of the patient. Treatment: Segmental resection of the advancing edge of the lesion was carried out. Outcome: The patient is disease free, with no evidence of further osteolysis, after six months of follow-up. Take-away Lessons: This article describes the exclusion-based approach adopted to diagnose a case of VBD, aiming to standardise a workup for the diagnosis.

show abstract

“…Thus, after surgical intervention, primary reconstruction should be delayed until dormancy of the disease and arrest of osteolysis is confirmed. [ 9 10 ]…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Dilemma of Vanishing Bone Disease - A Case Report and Review of Literature

Saxena

Gopalakrishnan

Rangarajan

et al. 2023

Annals of Maxillofacial Surgery

View full text Add to dashboard Cite

show abstract

“…The word “vanishing” has been used with respect to the disease's radiographic presentation. [ 4 ] It is characterized by uncontrolled, destructive proliferation of vascular or lymphatic capillaries within bone and surrounding soft tissue. [ 5 ] It affects patients ranging widely in age, from 2 months to 78 years, but most common in those under 40 years.…”

Section: Discussionmentioning

confidence: 99%

Vanishing bone disease

Saify

Gosavi²,

Jain

et al. 2021

Journal of Oral and Maxillofacial Pathology

View full text Add to dashboard Cite

Vanishing bone disease is a rare clinical entity with unknown etiology. This disease affects individual irrespective of age or sex. Various names have been used in the literature to describe this condition such as Gorham's disease, phantom bone disease, massive osteolysis, disappearing bone disease and acute spontaneous absorption of bone. The pathogenesis is unknown and the treatment still remains controversial. Considering the rarity of the disease, we report here an interesting and unique case of massive osteolysis of the lower jaw that affected the mandibular basal and alveolar bone. The diagnoses lead on the association of clinical, radiological and histological features.

show abstract

“…Severe complications of GSD including paraplegia or death in cases of osteolysis with vertebral involvement [4,7]; respiratory failure, hemothorax, or chylothorax in the cases of chest injury; or bacterial meningitis in cases of osteomeningeal breccia [2,12] are rare. In 16% of cases, this disease is fatal [13].…”

Section: Discussionmentioning

confidence: 99%

Ectopic teeth in a patient with Gorham-Stout disease previously treated by biphosphonates: a case report

Donne

Jaby

Farge

et al. 2020

J Oral Med Oral Surg

View full text Add to dashboard Cite

Introduction: Gorham-Stout disease is a rare idiopathic condition of the bone that is characterized by a massive and spontaneous osteolysis, with a vascular or lymphatic proliferation in bone, which is then replaced by fibrous tissue. Observation: a 16-year-old patient was referred to the maxillofacial surgery department to remove ectopic teeth bilaterally in the ramus. He had Gorham-Stout disease, managed for many years in orthopedic surgery department for a lower limb lesion and in neurosurgery department for a breach of the meninges. He was treated for 4 years with bisphosphonates. The removal of the ectopic teeth went well, with a simple postoperative course. Discussion: Gorham-Stout disease physiopathology remains unknown. Facial bones are often involved, especially the mandible. There are many possible treatments, but, due to the rarity of the disease, no therapeutic consensus exists. Bisphosphonates seem to be a good way to control this condition. So far, no case of bisphosphonates related osteonecrosis of the jaw has been reported in children. Conclusion: Gorham-Stout disease can involve the mandible and may lead to ectopic teeth.

show abstract

“Vanishing Bone Disease” in Maxillofacial Region: A Review and Our Experience

Cited by 11 publications

References 53 publications

Diagnostic Dilemma of Vanishing Bone Disease - A Case Report and Review of Literature

Diagnostic Dilemma of Vanishing Bone Disease - A Case Report and Review of Literature

Vanishing bone disease

Ectopic teeth in a patient with Gorham-Stout disease previously treated by biphosphonates: a case report

Contact Info

Product

Resources

About