Variabilidad en la práctica clínica: calidad de prescripción de los inhibidores de la bomba de protones

Appropriateness of the use of proton pump inhibitors in the Emergency Department of a Spanish university hospital

“…These factors might have influenced our data with regard to the appropriateness of the prescription. The usage rate by PPI type was similar to that reported in other Spanish studies (11,12,17). Omeprazole was the most widely used, at around 75%, although the rate should approach 100% as it is the first choice agent based on local recommendations (8).…”

“…Our results are in line with those of similar studies that demonstrate PPI overuse and inappropriate prescriptions, both in the inpatient and outpatient setting. The percentage of patients with a PPI prescription before visiting the ED (23.2%) was similar to patients seen in Primary Care (11,17) and inpatients admitted to the hospital (13,15,19); the prevalence of PPI prescription ranged from 18.6% to 34.6%. The proportion of patients admitted to the ED who were prescribed a PPI (71.4%) was similar to PPI usage studies among inpatients (12)(13)(14)(15)18,19); the prevalence of PPI use ranges from 64.8% to 82.6%.…”

“…The most recent studies have been performed in both the inpatient and outpatient setting (11)(12)(13)(14)(15)(16)(17)(18)(19)(20) and demonstrate the existence of PPI overuse. Furthermore, an important percentage of prescriptions (estimated at 25% in the European Union and 70% in the United States [3,18]) are not based on approved indications.…”

Anemia perniciosa y enfermedades tiroideas autoinmunes en una población mayor de 65 años

“…En cuanto a la temporalidad, nuestros datos muestran que en las mujeres el riesgo de que la AP preceda a las ATI es 6 veces mayor que en los hombres, lo que podría derivar en la recomendación de solicitar anticuerpos antitiroideos en este grupo poblacional de alto riesgo, recomendación ya mencionada en otros estudios 11,12 .…”

“…Según los datos del Sistema de Información de la Prestación Farmacéutica de Castilla y León (Informe CONCY-LIA) el consumo de ambos principios activos está entre los 8 más frecuentes especialmente en esta población 11 .…”