Variant-Specific Adsorption, Desorption, and Dissipation of Microcystin Toxins in Surface Soil

Abstract

Microcystins (MCs) are hepatotoxic heptapeptides identified in cyanobacterial bloom-impacted waters and soils. However, their environmental fate in soils is poorly understood, preventing reliable site assessment. This study aims to clarify the variant-specific adsorption, desorption, and dissipation of MC-LR and MC-RR in agricultural soils. Results revealed that their adsorption isotherms followed the Freundlich model (R 2 ≥ 0.96), exhibiting a higher nonlinear trend and lower adsorption capacity for MC-LR than for MC-RR. The soils had low desorption rates of 8.14−21.06% and 3.06−34.04%, respectively, following a 24 h desorption cycle. Pairwise comparison indicated that soil pH and clay played key roles in MC-LR adsorption and desorption, while organic matter and cation exchange capacity played key roles in those of MC-RR. MC-LR dissipation half-lives in soils were 27.18− 42.52 days, compared with 35.19−43.87 days for MC-RR. Specifically, an appreciable decrease in MC concentration in sterile soils suggested the significant role of abiotic degradation. This study demonstrates that the minor structural changes in MCs might have major effects on their environmental fates in agricultural soil and indicates that the toxic effects of MCs should be of high concern due to high adsorption, low desorption, and slow dissipation.

Chronic Exposure to Environmentally Relevant Concentrations of Microcystin-Leucine Arginine Causes Lung Barrier Damage through PP2A Activity Inhibition and Claudin1 Ubiquitination

“…Recent changes in ecological and environmental factors have contributed to an increased frequency, intensity, and duration of cyanobacterial water blooms . Microcystins (MCs), produced by cyanobacteria, have a toxic effect on humans and wildlife, which occurs through nontreated or improperly processed polluted food. − MCs have been detected in fish, mussels, and vegetables. , In addition, MCs can be transferred and accumulated to higher organisms through the food web . Surprisingly, microcystin-leucine arginine (MC-LR) was found in the serum of fishermen at concentrations of 0.10–0.64 μg/L .…”