Variation in global COVID-19 symptoms by geography and by chronic disease: A global survey using the COVID-19 Symptom Mapper

Kadirvelu, Balasundaram; Burcea, Gabriel; Quint, Jennifer; Costelloe, Céire; Faisal, A. Aldo

doi:10.1016/j.eclinm.2022.101317

Cited by 21 publications

(21 citation statements)

References 18 publications

(22 reference statements)

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“…In the same population of this study, in 2020,we proposed that symptoms suggestive of covid-19 vs. common cold or flu, were cough, fever, dyspnea, general pain, asthenia, nausea-vomiting, pneumonia [29]. On the other hand, it has been found that the frequency of the main symptoms in 2020 (cough, fever and loss of smell), was different depending on the country and the presence of underlying health conditions such as asthma and diabetes [11]. Thus, it must also be taken into account that the symptoms may not depend so much on the variant, but on how the organism reacts to the virus [30]; it could be said that not everything depends on the pathogen, but also on the host and environment [31].…”

Section: Resultsmentioning

confidence: 72%

“…Of these, 64,699 were symptomatic. Responders who tested positive were more likely to report joint pain, loss of appetite, and loss of smell and taste [11]. Along these same lines, we report in a study in the same population of the GP consultation that this study, from March 9 to April 3, 2020, where covid-19 diagnostic test was not initially performed, that patients who should be considered as probable covid-19 were those who presented fever, dyspnea, diarrhea, nausea / vomiting, or physical signs of pneumonia, with long duration of symptoms [29].…”

Section: Symptoms Of Covid At the Beginning Of The Pandemicmentioning

confidence: 99%

“…Research of covid-19 symptoms in 190 countries during 2020 showed that the frequency of symptoms of cough, fever, and loss of smell, was different depending on the country and the presence of underlying health conditions such as asthma and diabetes [11]. In addition, it seems that the symptoms with which covid-19 manifested itself at the beginning of the pandemic are no longer the same.…”

Section: Introductionmentioning

confidence: 99%

“…Likewise, the fact of being able to reflect this variation in symptoms in public health messages can contribute to prevention. It has been said that future work should focus on symptom profile variation in emerging SARS-CoV-2 virus variants [11].…”

Section: Introductionmentioning

confidence: 99%

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Covid-19 Breakthrough Infections In Vaccinated People With Vaccine Booster In 2022 Versus Covid-19 Cases In Unvaccinated People In 2020: A New Disease Whose Clinic we Should Know or Another Cause of The Old Symptoms of The Common Cold?

Turabián¹

2022

JGMCP

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Background It is not clear whether the symptoms of covid-19 have varied throughout the pandemic and what effect vaccination may have had. Objective To compare clinical-epidemiological characteristics between cases of covid-19 in 2020 without vaccination, and covid-19 breakthrough infections in vaccinated people with vaccine booster during 2022 in general medicine. Methodology Comparison of secondary data of cases of covid-19 without vaccination of previous studies in 2020, with other cases of covid-19 breakthrough infections in vaccinated people with vaccine booster in 2022, all of them carried out in the same population of patients treated in a general medicine office in Toledo, Spain. Results Cases of covid-19 breakthrough infections in vaccinated people with vaccine booster in 2022 (N= 46) vs. cases in 2020 without vaccination (N=100), differed statistically by being older, having more sociohealth workers, presenting more chronic diseases, and having more ENT symptoms and fewer digestive and psychiatric ones. Conclusions In the context of general medicine in Toledo (Spain), the cases of covid-19 in 2022 are different from those of 2020, affecting older people and showing symptoms of upper respiratory tract infection. This change in symptoms that causes covid-19 to present itself as a common cold can do away with preventive precautions, so it is important to test to see what the symptoms mean.

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Section: Resultsmentioning

confidence: 72%

Section: Symptoms Of Covid At the Beginning Of The Pandemicmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Covid-19 Breakthrough Infections In Vaccinated People With Vaccine Booster In 2022 Versus Covid-19 Cases In Unvaccinated People In 2020: A New Disease Whose Clinic we Should Know or Another Cause of The Old Symptoms of The Common Cold?

Turabián¹

2022

JGMCP

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“…COVID-19 is a viral respiratory disease with increasing mortality with increasing age of patients and occurring comorbidities such as obesity, diabetes and immune deficiency [ 15 , 16 , 17 ]. The disease has typical indicators of shortness of breath (dyspnea), fever, fatigue and cough, but other manifestations can occur depending on the variant of COVID-19 and individual dispositions, and some post-COVID-19 syndromes can remain even after the infection resolves [ 18 , 19 , 20 , 21 , 22 , 23 ]. An increase in inflammatory cytokines and the appearance of symptoms after inflammation is also typical for COVID-19 [ 24 , 25 , 26 , 27 , 28 ].…”

Section: Current Point-of-care Tests For Covid-19mentioning

confidence: 99%

Progress in Biosensors for the Point-of-Care Diagnosis of COVID-19

Pohanka

2022

Sensors

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Coronavirus disease 2019 (COVID-19) is a highly virulent infection that has caused a pandemic since 2019. Early diagnosis of the disease has been recognized as one of the important approaches to minimize the pathological impact and spread of infection. Point-of-care tests proved to be substantial analytical tools, and especially lateral flow immunoassays (lateral flow tests) serve the purpose. In the last few years, biosensors have gained popularity. These are simple but highly sensitive and accurate analytical devices composed from a selective molecule such as an antibody or antigen and a sensor platform. Biosensors would be an advanced alternative to current point-of-care tests for COVID-19 diagnosis and standard laboratory methods as well. Recent discoveries related to point-of-care diagnostic tests for COVID-19, the development of biosensors for specific antibodies and specific virus parts or their genetic information are reviewed.

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Challenges Based on Antiplasmodial and Antiviral Activities of 7‐Chloro‐4‐aminoquinoline Derivatives

et al. 2023

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We report the structural functionalization of the terminal amino group of N 1 -(7-chloroquinolin-4-yl) butane-1,4-diamine, leading to a series of 7-chloro-4-aminoquinoline derivatives, and their evaluation as potent anti-malarial and anti-viral agents. Some compounds exhibited promising anti-malarial effects against the Plasmodium falciparum 3D7 (chloroquine-sensitive) and Dd2 (chloroquine-resistant) strains. In addition, these compounds were assayed in vitro against influenza A virus (IAV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Compound 5 h, bearing an N-mesityl thiourea group, displayed pronounced anti-infectious effects against malaria, IAV, and SARS-CoV-2. These results provide new insights into drug discovery for the prevention or treatment of malaria and virus co-infection.

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Variation in global COVID-19 symptoms by geography and by chronic disease: A global survey using the COVID-19 Symptom Mapper

Cited by 21 publications

References 18 publications

Covid-19 Breakthrough Infections In Vaccinated People With Vaccine Booster In 2022 Versus Covid-19 Cases In Unvaccinated People In 2020: A New Disease Whose Clinic we Should Know or Another Cause of The Old Symptoms of The Common Cold?

Covid-19 Breakthrough Infections In Vaccinated People With Vaccine Booster In 2022 Versus Covid-19 Cases In Unvaccinated People In 2020: A New Disease Whose Clinic we Should Know or Another Cause of The Old Symptoms of The Common Cold?

Progress in Biosensors for the Point-of-Care Diagnosis of COVID-19

Challenges Based on Antiplasmodial and Antiviral Activities of 7‐Chloro‐4‐aminoquinoline Derivatives

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