Variation in Lifestyle-Related Behavior Among Obese Indian Patients With Non-alcoholic Fatty Liver Disease

Abstract

Lifestyle modification is the mainstay of treatment in Non-Alcoholic Fatty Liver Disease (NAFLD). Published Indian data on the diet and lifestyle of Indian NAFLD patients is scarce. This study explored variation in lifestyle-related behavior among obese patients with NAFLD. Ultrasonography (USG) diagnosed obese NAFLD patients (n = 140) were assessed for dietary intake [1-day 24 hours recall, food-frequency questionnaire (FFQ)] and physical activity (PA) [Global Physical Activity Questionnaire (GPAQ)]. Diet quality score (0–30) and physical activity (PA) levels were used to study variation in lifestyle and assess the effect of lifestyle on the severity of NAFLD. Compared to the recommendation, calorie consumption was 25.2% higher in nearly half (53.6%) of the subjects and mean macronutrient intake was imbalanced (60.3% carbohydrates, 12.4% protein, 25.5% fats). Variation was seen in terms of diet quality—good (3%), moderate (54.3%), or poor (43.5%) and intensity of PA—high (15%), moderate (47.9%), or low (37.1%). No patient had a combination of high PA and good diet quality within all grades of NAFLD. Our study suggests wide variation in lifestyles of obese patients with NAFLD and need for a more flexible and individualized modification of their diet and PA.

Novel Multi-Ingredient Supplement Facilitates Weight Loss and Improves Body Composition in Overweight and Obese Individuals: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

“…Herein, we found that AST and ALT levels were significantly lower after the intervention period in the MIS treatment arm. Arora and colleagues (2022) demonstrated that ALT levels decrease in correlation with weight loss in patients with obesity and NAFLD, who followed a lifestyle intervention for six months [126]. Similarly, weight loss stemming from low energy intake has been shown to facilitate an improvement in AST [127].…”

A Review on the Role of Low Glycemic Index Foods for Glycemic Control in Chronic Liver Disease

“…People are not well-aware about the nutritional value of their regular dietary choices. An Indian study on 140 obese patients with NAFLD reported that choice of full cream milk (60.0%), daily consumption of high sugar (59.3%) along with honey, and/or jaggery, sugar-sweetened beverages and fruit juices (thrice/week) (32.0%), and regular consumption of fast food, bakery products (55.0%) and fried Indian savory snacks (44.3%) are very common [62]. Consumption of excess refined sugar and high-fructose corn syrup lead to increased liver fat, and development of NAFLD [63].…”