Variations in prevalence estimates of epiretinal membranes

Cheung, Ning; Wang, J J; Wong, Tien‐Yin

doi:10.1038/sj.eye.6702905

Cited by 4 publications

(2 citation statements)

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“…Knowledge about the epidemiology of ERM among Asians is limited 5. The SEED study represents the largest study to date that provides contemporary population-based data on the prevalence and risk factors of both primary and secondary ERM in a multiethnic Asian population.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and risk factors for epiretinal membrane: the Singapore Epidemiology of Eye Disease study

et al. 2016

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Section: Discussionmentioning

confidence: 99%

Prevalence and risk factors for epiretinal membrane: the Singapore Epidemiology of Eye Disease study

et al. 2016

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“…In recent years, studies among different ethnic groups have provided population-based prevalence data on ERM, ranging from 1.0% to 28.9%589101112131415161718. Despite much effort in epidemiologic, clinical and laboratory research, the pathogenesis and risk factors for ERM remain incompletely understood.…”

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confidence: 99%

The Association between Smoking and Epiretinal Membrane

Wang

Tong

Wang

et al. 2016

Sci Rep

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We conducted a meta-analysis of analytic and observational studies to evaluate the association between smoking and epiretinal membrane (ERM). The pertinent studies were identified via a literature search using three databases (MEDLINE, Cochrane Library, Embase) and the reference lists of retrieved studies. Cohort, case-control and cross-sectional studies meeting the predefined criteria were included. We extracted the odds ratios (OR) and 95% confidence intervals (CI) from each study. Overall risk estimates were pooled using random-effects models. Subgroup analyses based on several stratified factors were also performed. Two cohort studies and six cross-sectional studies involving 46,837 subjects were included. The pooled effect of all eight studies showed an unexpected significant decreased association between smoking and the occurrence of ERM (OR, 0.72; 95% CI 0.61–0.84; p = 0.29, I2 = 17.9%). Subgroup analyses supported this finding, except for the age-unadjusted group (OR, 0.87; 95% CI 0.63–1.22), the ERM classification group (cellophane macular reflex (CMR) OR, 0.93; 95% CI 0.68–1.28; preretinal macular fibrosis (PMF) OR, 0.74; 95% CI 0.41–1.32), the Asian group (OR, 0.75; 95% CI 0.52–1.09) and the past smoker group (OR, 1.02; 95% CI 0.85–1.22). The pooled effects from the current literature suggested a declining association between smoking and ERM, which requires further studies to confirm.

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