Variations of dry eye disease prevalence by age, sex and geographic characteristics in China: a systematic review and meta-analysis

Song, Peige; Xia, Wei; Wang, Manli; Chang, Xiaoxia; Jing-pin, Wang; Su, Jin; Wang, Jiawen; Wei, Wei; Rudan, Igor

doi:10.7189/jogh.08.020503

Cited by 102 publications

(127 citation statements)

References 48 publications

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“…DED by symptoms and signs was defined as a positive symptom with at least one positive clinical sign tested by tear film breakup time ≤10 s, Schirmer's I test ≤10 s or fluorescein staining ≥1, whereas DED by symptoms only relied on the presence of self-reported positive symptoms. These results support that, despite advanced age, female sex and larger latitude were significant risk factors for dry eye based on symptoms and signs; only advanced age was positively associated with an increased prevalence of DED by symptoms [50].…”

Section: Risk Factorssupporting

confidence: 78%

Dry Eye Disease: A Review of Epidemiology in Taiwan, and its Clinical Treatment and Merits

Kuo

Lin

Chien

et al. 2019

JCM

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Dry eye disease (DED) has become common on a global scale in recent years. There is a wide prevalence of DED in different countries based on various ethnicities and environment. DED is a multifactorial ocular disorder. In addition to advanced age and gender, such factors as living at high altitude, smoking, pterygium, prolonged use of consumer electronics or overingesting of caffeine or multivitamins are considered to be the major risk factors of DED. We report the DED epidemiology in Taiwan firstly in this article. According to the pathophysiological factors and changes inthe composition of the tear film in DED, it can be categorized into several subtypes, including lipid anomaly dry eye, aqueous tear deficiency, allergic and toxic dry eye among others. Each subtype has its own cause and disease management; therefore, it is important for ophthalmologists to identify the type through literature review and investigation. The management of DED, relies not only on traditional medications such as artificial tears, gels and ointments, but also newer treatment options such as acupuncture, SYL1001, and nanomedicine therapy. We also conducted a comprehensive literature review including common subtypes and treatment of DED. Clearly, more clinical trials are needed to assess the efficacy and safety of the various treatments and common subtypes of DED.

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Section: Risk Factorssupporting

confidence: 78%

Dry Eye Disease: A Review of Epidemiology in Taiwan, and its Clinical Treatment and Merits

Kuo

Lin

Chien

et al. 2019

JCM

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“…[38] As anticipated, the majority of cases with fungal keratitis occurred during the warmer months, which is consistent with the results of previous studies conducted in both developed and developing countries. [15,39] In conclusion, bacteria were the most prevalent etiology of infectious corneal ulcers in South Texas. Coagulase-negative Staphylococcus and Pseudomonas were the most common bacterial isolates; this result is consistent with the results of other studies reporting the etiologies of bacterial keratitis in populations across the United States and the world.…”

Section: Dei-la Doheny Eye Institute -Los Angeles Lac + Usc-la Los Anmentioning

confidence: 89%

Etiology and Risk Factors for Infectious Keratitis in South Texas

Puig

Weiss

Salinas

et al. 2020

JOVR

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Purpose: To determine the causative organisms and associated risk factors for infectious keratitis in South Texas. Methods: This retrospective study was performed at a tertiary teaching hospital system in South Texas. Medical records of all patients who presented with infectious keratitis from 2012 to 2018 were reviewed. Only patients with culture-proven bacterial, fungal, and Acanthamoeba keratitis were included. Results: In total, 182 eyes of 181 patients had culture-proven bacterial, fungal, or Acanthamoeba keratitis. The age of patients ranged from 3 to 93 years, with a mean of 48.3 ± 20.8 years. The most common etiologic agent was bacteria, with 173 bacterial cultures (95.1%) recovered, followed by 13 fungal cultures (7.1%), and 3 Acanthamoeba cultures (1.6%). Of the 218 bacterial isolates, coagulase-negative Staphylococcus was the most common (25.7%), followed by Pseudomonas aeruginosa (23.4%), Staphylococcus aureus (11.0%), and Moraxella (7.8%). Fusarium was the most common fungal isolate (46.2%). The most common risk factors for infectious keratitis included contact lens wear (32.4%), underlying corneal disease (17.6%), trauma (14.3%), and ocular surface disease (13.7%). Conclusions: Bacteria are the most common cause of infectious keratitis in this patient population, with coagulase-negative Staphylococcus and Pseudomonas as the most common isolates. The prevalence of culture-positive fungal keratitis is significantly lower than that of bacterial keratitis. Contact lens wear is the most common risk factor associated with infectious keratitis in South Texas.

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“…Along the years there have been many efforts to generate reliable statistics on the prevalence of dry eye syndrome, unfortunately with significant differences between them. It is possible to find reports for Europe [4], United Sates of America [5,6], Africa [7], China [8], India [9], Ecuador [10], Canada [11], Japan [12], and Germany [13], among other countries. Unfortunately most countries remains poorly studied.…”

Section: Introductionmentioning

confidence: 99%

Control System Applied to the Microinjection of Artificial Tears for Severe Dry Eye Treatment

Meni-Babakidi¹,

Viramontes-Gamboa²,

Ibarra-Bracamontes³

et al. 2020

Applied Sciences

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This paper presents a portable automated teardrop microinjection system as a practical solution for patients suffering from severe dry eye. The electronic device for the controlled and continuous injection of artificial tears is designed, assembled, and tested for performance and stability. It is controlled via Wi-Fi from an Android programmable device. Its design is based on the physicochemical properties of artificial tears, and with both production costs and portability in mind. The system was modeled according to the V methodology of the association for professional German engineers VDI 2206 standard. The microinjector handles a wide range of internal variables such as tears flow rate (0.13 to 60 μL/min), tears viscosity (up to 600 Pa·s), temperature (up to 60 °C), injected volume of tears, and time between consecutive injections. For evaluation purposes, a comprehensive set of experimental tests were carried out to the system, comparing the actually delivered amount of tears, flow rate, and prescribed time vs. programmed values, the error was ∼0.2% for commercially available artificial tears.

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Variations of dry eye disease prevalence by age, sex and geographic characteristics in China: a systematic review and meta-analysis

Cited by 102 publications

References 48 publications

Dry Eye Disease: A Review of Epidemiology in Taiwan, and its Clinical Treatment and Merits

Dry Eye Disease: A Review of Epidemiology in Taiwan, and its Clinical Treatment and Merits

Etiology and Risk Factors for Infectious Keratitis in South Texas

Control System Applied to the Microinjection of Artificial Tears for Severe Dry Eye Treatment

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