Vascular Risk Factors and Mild Cognitive Impairment in the Elderly Population in Southwest China

Abstract

Hypertension, CHD, TC, and LDL-C are independent risk factors for MCI. Moreover, patients with vascular diseases have a higher risk of MCI; however, the amount of vascular diseases does not increase the risk of MCI.

Association between serum non-high-density lipoprotein cholesterol and cognitive impairment in patients with acute ischemic stroke

“…Dyslipidemia is not only an independent and maybe the most important risk factor for ischemic stroke, which tends to cause hidden, progressive, and somatic organic damage, but also affects the cognitive function of patients with ischemic stroke through accelerating systemic atherosclerosis, and it is believed to be a risk factor inducing cognitive disorders, even dementia [5]. …”

Glucose hypometabolism is highly localized, but lower cortical thickness and brain atrophy are widespread in cognitively normal older adults

“…Therefore, the primary aim of the present study was to quantify the magnitude of regional CMRg (mol·100 g Ϫ1 ·min Ϫ1 ), including PVE correction, in young and older adults who were cognitively normal for their age. Hypertension and mild metabolic dysregulation are common in the elderly and are important risk factors for the development of Alzheimer's disease (20,50). Scaled age-corrected scores were compared between the two groups to determine whether cognitive deficits were present in the older participants.…”

The association between cognitive decline and short-term blood pressure variability in middle-aged patients with primary hypertension — a pilot study

“…The relationship among hypertension and cognitive function is complex, albeit has not been fully www.ah.viamedica.pl [15,[31][32][33][34][35][36]. Numerous studies addressed this issue to specific blood pressure cut-offs, or more recently -exclusively to systolic blood pressure values [13,14,16,31]. In this pilot study, we investigated a potential role of short-term blood pressure variations in cognitive impairments.…”

“…However, some cross-sectional studies suggest an adverse effect of hypertension on cognitive functions also in the younger age groups [9][10][11]. Earlier reports demonstrated that accumulated blood pressure load proportionally increase the risk of cerebrovascular complications including VD [12][13][14][15][16][17][18][19][20], and the enhanced analysis of conventional 24-hour ambulatory blood pressure monitoring (ABPM) data may be useful in predicting cardio-and cerebrovascular outcomes [21][22][23][24][25]. It has been showed that the assessment of short-term systolic blood pressure variability (BPV) and pulse pressure (PP) substantially increase the prognostic value of data derived from conventional ABPM [26].…”