Vascularised fibular grafts for reconstruction of extremity bone defects after resection of bone and soft-tissue tumours

Abstract

Although associated with a relatively high rate of complications, each reconstruction method is useful, with a high rate of successful limb salvage and a good long-term functional outcome. Cite this article: 2017;99-B:1237-43.

Free vascularized fibula grafting in the operative treatment of malignant bone tumors of the upper extremity: A systematic review of outcomes and complications

“…Reconstruction by prosthesis is the most commonly used technique following sarcoma resection due to the relatively low rate of postoperative complications . However, reconstruction with prosthesis is burdened by long‐term problems such as mechanical failure, aseptic loosening, and late infection, which limit the long‐term survival of the prosthesis and often necessitate its removal or amputation .…”

“…53,74,75 Reconstruction by prosthesis is the most commonly used technique following sarcoma resection due to the relatively low rate of postoperative complications. 76 However, reconstruction with prosthesis is burdened by long-term problems such as mechanical failure, aseptic loosening, and late infection, which limit the long-term survival of the prosthesis and often necessitate its removal or amputation. [76][77][78][79][80] Biologic reconstruction, on the other hand, has a relatively high complication rate and causes significant functional restriction during the early postoperative period, but can result in improved long-term functionality after cortical union is achieved.…”

“…76 However, reconstruction with prosthesis is burdened by long-term problems such as mechanical failure, aseptic loosening, and late infection, which limit the long-term survival of the prosthesis and often necessitate its removal or amputation. [76][77][78][79][80] Biologic reconstruction, on the other hand, has a relatively high complication rate and causes significant functional restriction during the early postoperative period, but can result in improved long-term functionality after cortical union is achieved. 76,81 Careful patient selection based on published clinical evidence should be used to develop the optimal individualized treatment plan for each patient.…”

Advances in Synthesis and Functional Modification of Nanohydroxyapatite

“…Chitosan (CS) is a rare and positively charged alkaline polysaccharide. It is a product of deethylation (1)(2)(3)(4), and its chemical name is 2-amino-2-deoxy-beta-d-glucose. By using chitosan as the template, the nano-HA with class spindle is prepared.…”

“…Tumors, trauma, congenital developmental deformities, and severe inflammatory diseases often have varying degrees of bone tissue defects [1][2][3][4]. Bone allograft immunogenicity cannot prevent trauma and pain of patients undergoing bone transplantation; thus, using apatite as a bone repair replacement material has become one of the important methods of bone repair replacement [5,6].…”