Vascularity depicted by contrast-enhanced ultrasound predicts recurrence of papillary thyroid cancer

Li, Wen; Li, Yang; Long, Minnan; Li, Jie; Ma, Jun; Luo, Yukun

doi:10.1016/j.ejrad.2022.110667

Cited by 3 publications

(2 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hypervascularity in ultrasound is an independent risk factor for recurrence in papillary thyroid carcinoma[ 78 ].…”

Section: Pre/postoperative Prediction Factors-recurrencementioning

confidence: 99%

Role of prophylactic central neck lymph node dissection for papillary thyroid carcinoma in the era of de-escalation

Pavlidis¹,

Pavlidis²

2023

World J Clin Oncol

View full text Add to dashboard Cite

It is now well established that the biology of cancer is influenced by not only malignant cells but also other components of the tumour microenvironment. Chronic inflammation and fibrosis have long been postulated to be involved in carcinogenesis. Chronic inflammation can promote tumorigenesis via growth factor/cytokine-mediated cellular proliferation, apoptotic resistance, immunosuppression; and free-radical-induced oxidative deoxyribonucleic acid damage. Fibrosis could cause a perturbation in the dynamics of the tumour microenvironment, potentially damaging the genome surveillance machinery of normal epithelial cells. In this review, we will provide an in-depth discussion of various diseases characterised by inflammation and fibrosis that have been associated with an increased risk of malignancy. In particular, we will present a comprehensive overview of the impact of alterations in stromal composition on tumorigenesis, induced as a consequence of inflammation and/or fibrosis. Strategies including the application of various therapeutic agents with stromal manipulation potential and targeted cancer screening for certain inflammatory diseases which can reduce the risk of cancer will also be discussed.

show abstract

“…Hypervascularity in ultrasound is an independent risk factor for recurrence in papillary thyroid carcinoma[ 78 ].…”

Section: Pre/postoperative Prediction Factors-recurrencementioning

confidence: 99%

Role of prophylactic central neck lymph node dissection for papillary thyroid carcinoma in the era of de-escalation

Pavlidis¹,

Pavlidis²

2023

World J Clin Oncol

View full text Add to dashboard Cite

show abstract

“…According to prior research, contrastenhanced ultrasound revealed an incidence of thyroid nodules of about 20%-76% during screening, and a diagnostic rate of PTC of about 5%-15%, and it is becoming the first choice for detection and diagnosis of CLNM in PTC patients [10]. Another study also reported that preoperative ultrasound could help diagnose CLNM in PTC to some extent [11]. In routine ultrasound examinations, tumor size, capsule infiltration, nodular microcalcification, and multiple foci are all important risk factors for CLNM [12].…”

Section: Introductionmentioning

confidence: 99%

Clinical value of ultrasound parameters PI, TTP, and MTT in assessing cervical lymph node metastasis of papillary thyroid carcinoma

Kong

2024

Am J Transl Res

View full text Add to dashboard Cite

Objective: To determine the clinical value of ultrasound in assessing cervical lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC). Methods: The medical records of 179 PTC patients treated in Shandong Provincial Qianfoshan Hospital between March 2016 and March 2019 were collected. The patients were assigned to a transfer group (54 cases) and a non-transfer group (125 cases) according to their pathologic results. The ultrasound parameters (peak intensity (PI), time to peak (TTP), and mean transit time (MTT)) of the two groups were compared. Then, multivariate logistic regression was used to analysis the results, and receiver operating characteristic (ROC) curves were plotted to evaluate the value of risk factors in predicting CLNM. Results: The transfer group showed notably lower PI, TTP and MTT than the non-transfer group (P<0.001), and focus diameter, microcalcification, multiple foci, PI, TTP, and MTT were identified as independent risk factors for LNM in patients (P<0.05). According to the ROC curve, the areas under the curves (AUCs) of microcalcification, multiple foci, and PI were all smaller than 0.7; the AUCs of focus diameter and MTT were smaller than 0.8, and the AUC of TTP was 0.855. Conclusion: PI, TTP, and MTT all decrease in PTC patients with CLNM, and TTP has a strong predictor for CLNM in them, with an AUC of 0.855.

show abstract

Radiofrequency ablation for capsular-located versus noncapsular-located papillary thyroid microcarcinoma: a propensity score matching study of 1095 patients

Jing,

Yan,

Xiao

et al. 2024

Eur Radiol

View full text Add to dashboard Cite

Vascularity depicted by contrast-enhanced ultrasound predicts recurrence of papillary thyroid cancer

Cited by 3 publications

References 36 publications

Role of prophylactic central neck lymph node dissection for papillary thyroid carcinoma in the era of de-escalation

Role of prophylactic central neck lymph node dissection for papillary thyroid carcinoma in the era of de-escalation

Clinical value of ultrasound parameters PI, TTP, and MTT in assessing cervical lymph node metastasis of papillary thyroid carcinoma

Radiofrequency ablation for capsular-located versus noncapsular-located papillary thyroid microcarcinoma: a propensity score matching study of 1095 patients

Contact Info

Product

Resources

About