Vasculite leucocitoclástica e infecção crónica por Hepatite B

Abstract

ResumoOs autores apresentam o caso clínico de uma doente de 79 anos, internada para estudo de uma vasculite, cuja investigação etiológica nos levou a ponderar a associação com hepatite B crónica. A vasculite leucocitoclás-tica pode ter variadas etiologias. A associação com hepatite vírica é mais frequente com a hepatite C, havendo no entanto alguns casos relatados sobre a associação à hepatite B. A etiologia vírica tem de ser sempre considerada nestas situações, pois a resolução do quadro pode passar pelo tratamento da patologia de base.Palavras chave: Vasculitis leucocitoclàstica. Hepatitis B crònica. Crioglobulinas. AbstractThe authors present a case report of a 79 year old patient who was admitted for the study of vasculitis, whose etiological investigation led us to consider the association with chronic hepatitis B infection. Leucocytoclastic vasculitis may have varied etiologies. The association with viral hepatitis is more common with hepatitis C, but there are some cases reported about the association with hepatitis B. The viral etiology must always be considered in such situations because the case resolution can implicate the treatment of the underlying disease.

Leukocytoclastic vasculitis due to reactivation of virus varicella zoster. Case report

“…Pharmacological etiology of LCV is performed by exclusion, since it is presumed that some drugs act as haptens, among many drugs, the famciclovir is one of them. 13 When ruling out the drug cause, viral infections should be considered as a trigger, especially if there is no other apparent factor, 23 even when the infection is not clinically tangible. The spread of the varicellazoster virus is a complication of variable frequency with high morbidity that requires rapid management based on high clinical suspicion.…”