Vat photopolymerization 3D printed microfluidic devices for organ-on-a-chip applications

Milton, Laura A.; Viglione, Matthew; Ong, Louis Jun Ye; Nordin, Gregory P.; Toh, Yi‐Chin

doi:10.1039/d3lc00094j

Cited by 29 publications

(11 citation statements)

References 184 publications

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“…Although DLW 3D printers lack the print fields and build volumes of their VPP counterparts, 201 there are microfluidic applications for which it is advantageous to: (i) DLW-print 3D millimetre- or submillimetre-scale microfluidic components onto a sacrificial substrate ( Fig. 7a – left ), (ii) release the DLW-printed components from the substrate ( Fig.…”

Section: Dlw Of Millimetre- and Submillimetre-scale Microfluidic Comp...mentioning

confidence: 99%

Direct laser writing-enabled 3D printing strategies for microfluidic applications

Young,

Xu,

Sarker

et al. 2024

Lab Chip

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Section: Dlw Of Millimetre- and Submillimetre-scale Microfluidic Comp...mentioning

confidence: 99%

Direct laser writing-enabled 3D printing strategies for microfluidic applications

Young,

Xu,

Sarker

et al. 2024

Lab Chip

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“…Among the many AM processes, mask image projection-based vat photopolymerization (MIP-VPP) is increasingly used in industries such as dental, biomedical, and consumer devices, to name a few, due to its ability for high-speed [3,4], largescale [5][6][7], and high-resolution [8][9][10][11] fabrication using digitally patterned ultra-violet (UV) radiation to initiate localized photopolymerization and transform liquid resin into solid products. The versatility of this approach significantly extends the application range of MIP-VPP, moving beyond structural prototyping to various functional product manufacturing, such as microfluidic devices, micro-robotics, optics, and sensors, among others [8,9,[12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Vibration-assisted vat photopolymerization for pixelated-aliasing-free surface fabrication

Xu,

Hu,

Chen

et al. 2024

Int. J. Extrem. Manuf.

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Mask image projection-based vat photopolymerization (MIP-VPP) offers advantages like low cost, high resolution, and a wide material range, making it popular in industry and education. Recently, MIP-VPP employing liquid crystal displays (LCDs) has gained traction, increasingly replacing digital micromirror devices (DMDs), particularly among hobbyists and in educational settings, and is now beginning to be used in industrial environments. However, LCD-based MIP-VPP suffers from pronounced pixelated aliasing arising from LCD's discrete image pixels and its direct-contact configuration in MIP-VPP machines, leading to rough surfaces on the 3D-printed parts. Here, we propose a vibration-assisted MIP-VPP method that utilizes a microscale vibration to uniformize the light intensity distribution of the LCD-based mask image on VPP’s building platform. By maintaining the same fabrication speed, our technique generates a smoother, non-pixelated mask image, reducing the roughness on flat surfaces and boundary segments of 3D-printed parts. Through light intensity modeling and simulation, we derived an optimal vibration pattern for LCD mask images, subsequently validated by experiments. We assessed the surface texture, boundary integrity, and dimensional accuracy of components produced using the vibration-assisted approach. The notably smoother surfaces and improved boundary roughness enhance the printing quality of MIP-VPP, enabling its promising applications in sectors like the production of 3D-printed optical devices and others.

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“…The applications of vat photopolymerization include the manufacturing of high-detail prototypes and jewelry and the small-scale manufacturing of complex parts. Additionally, drug delivery systems, dental implants, crowns, bone models, microfluidic devices, and scaffolds for tissue engineering are among the biomedical applications [12][13][14][15][16].…”

Section: Introduction 1additive Manufacturingmentioning

confidence: 99%

Powder Bed Fusion 3D Printing in Precision Manufacturing for Biomedical Applications: A Comprehensive Review

Joshua,

Raj,

Hameed Sultan

et al. 2024

Materials

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Precision manufacturing requirements are the key to ensuring the quality and reliability of biomedical implants. The powder bed fusion (PBF) technique offers a promising solution, enabling the creation of complex, patient-specific implants with a high degree of precision. This technology is revolutionizing the biomedical industry, paving the way for a new era of personalized medicine. This review explores and details powder bed fusion 3D printing and its application in the biomedical field. It begins with an introduction to the powder bed fusion 3D-printing technology and its various classifications. Later, it analyzes the numerous fields in which powder bed fusion 3D printing has been successfully deployed where precision components are required, including the fabrication of personalized implants and scaffolds for tissue engineering. This review also discusses the potential advantages and limitations for using the powder bed fusion 3D-printing technology in terms of precision, customization, and cost effectiveness. In addition, it highlights the current challenges and prospects of the powder bed fusion 3D-printing technology. This work offers valuable insights for researchers engaged in the field, aiming to contribute to the advancement of the powder bed fusion 3D-printing technology in the context of precision manufacturing for biomedical applications.

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Vat photopolymerization 3D printed microfluidic devices for organ-on-a-chip applications

Abstract: Organs-on-a-chip, or OoCs, are microfluidic tissue culture devices with micro-scaled architectures that repeatedly achieve biomimicry of biological phenomena. They are well positioned to become the primary pre-clinical testing modality as...

Cited by 29 publications

References 184 publications

Direct laser writing-enabled 3D printing strategies for microfluidic applications

Direct laser writing-enabled 3D printing strategies for microfluidic applications

Vibration-assisted vat photopolymerization for pixelated-aliasing-free surface fabrication

Powder Bed Fusion 3D Printing in Precision Manufacturing for Biomedical Applications: A Comprehensive Review

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