Vegetable Juices and Fibers Reduce Lipid Digestion or Absorption by Inhibiting Pancreatic Lipase, Cholesterol Solubility and Bile Acid Binding

Trisat, Kanittaporn; Wongon, Matusorn; Lapphanichayakool, Phakhamon; Tiyaboonchai, Waree; Limpeanchob, Nanteetip

doi:10.1080/19315260.2016.1258604

Cited by 20 publications

(17 citation statements)

References 27 publications

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“…More recently, the juice of onion was also tested for its lipase inhibitory potential. Onions were cut into small pieces, blended with water and centrifuged [81]. Sample was demonstrated to inhibit pancreatic lipase with an IC 50 value equal to 9.5 mg/mL…”

Section: Beneficial Effects Of Onion In the Treatment Of Obesitymentioning

confidence: 99%

Biological Properties and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the Treatment of Obesity and Related Comorbidities

et al. 2018

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Common onion (Allium cepa L.) is one of the oldest cultivated plants, utilized worldwide as both vegetable and flavouring. This species is known to contain sulphur amino acids together with many vitamins and minerals. A variety of secondary metabolites, including flavonoids, phytosterols and saponins, have also been identified. Despite the predominant use of this plant as food, a wide range of beneficial effects have also been proved. Different biological properties, such as antioxidant, antimicrobial and antidiabetic, have been reported. The aim of this review is to provide an overview of the studies concerning the beneficial effects of this species against obesity and its related comorbidities, such as hyperlipidaemia, hypertension and diabetes. Both in vitro and in vivo results about onion dietary supplementation have been taken into account. Furthermore, this review examines the possible role of onion bioactive components in modulating or preventing weight-gain or related diseases, as well as the possible mechanisms behind their activity.

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Section: Beneficial Effects Of Onion In the Treatment Of Obesitymentioning

confidence: 99%

Biological Properties and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the Treatment of Obesity and Related Comorbidities

et al. 2018

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“…The exception are root vegetables with stored carbohydrates, such as beetroot ( Beta vulgaris L.) and carrots ( Daucus carota L.). Most VJ is rich in the antioxidants, vitamins A, B, C, and E; lycopene, which gives tomato ( Solanum lycopersicum L.) red color; and calcium, potassium, and magnesium (Bayindirli, 2010; Marcus, 2013; Singh et al., 2020; Trisat et al., 2017). Dietary products aiding in lipid digestion and absorption inhibitory activities may be beneficial for human health (Trisat et al., 2017).…”

Section: Introductionmentioning

confidence: 99%

“…Most VJ is rich in the antioxidants, vitamins A, B, C, and E; lycopene, which gives tomato ( Solanum lycopersicum L.) red color; and calcium, potassium, and magnesium (Bayindirli, 2010; Marcus, 2013; Singh et al., 2020; Trisat et al., 2017). Dietary products aiding in lipid digestion and absorption inhibitory activities may be beneficial for human health (Trisat et al., 2017). Sweet basil ( Ocimum basilicum L.) juice was the most effective pancreatic lipase inhibitor and wildbetal leaf bush ( Piper sarmentosum Roxb.)…”

Section: Introductionmentioning

confidence: 99%

Rheological and physicochemical properties of vegetable juices and concentrates: A review

Salehi

2021

J. Food Process. Preserv.

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This review, summarizes the physicochemical and rheological properties (RP) of beetroot (Beta vulgaris L.), carrot (Daucus carota L.), celery (Apium graveolens L.), coriander (Coriandrum sativum L.), fenugreek (Trigonella foenum‐graecum L.), kale (Brassica oleracea L.), spinach (Spinacia oleracea L.), and tomato (Solanum lycopersicum L.) juices, and their concentrates. Carbohydrates, crude fiber, organic acids (ascorbic, citric, malic, and oxalic acids), vitamins (A, B, C, and E), minerals (calcium, potassium, and magnesium), amino acids, and phenolic compounds (PC) are major constituents of vegetable juice (VJ). If consumed in sufficient amount, VJs contribute to nutritional requirements for good health in humans. Vegetable concentrates are typically non‐Newtonian fluids in which the apparent viscosity decreases with increasing shear rate. The apparent viscosity of VJs decreases at higher temperatures. Several equations are employed to describe flow behavior, but most are difficult to use and none give good overall agreement with experimental data from Power‐law and Herschel–Bulkley models. The effect of temperature on apparent viscosity of VJ is generally expressed by the Arrhenius relationship and the activation energy (Ea) for the fluid flow increases with concentration. The Ea values reported for the vegetable products were between 3.6 and 39.7 kJ∙mol−1∙K−1. Higher Ea indicates apparent viscosity is more prone to temperature change. Practical applications Juice can be extracted from fresh vegetables to be used without further change or as concentrates in value added products. Rheological study of vegetable juice, in part how it flows, is important to handling and processing, quality control, and sensory evaluation of derived products. In this study, properties of vegetable juices and concentrates were reviewed. Vegetable concentrates are typically non‐Newtonian fluids. The Power‐law and Herschel–Bulkley models were successfully applied to fit data. Arrhenius model parameters for some VJs at different concentrations were reported in this study. Higher activation energy indicates viscosity is more prone to temperature change. The activation energy values for the vegetable products were between 3.6 and 39.7 kJ/mol∙K.

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“…O intestino e o fígado, em conjunto, possuem um papel importante no controle do metabolismo lipídico; no lúmen intestinal, o colesterol presente é derivado de muitas fontes: dieta, bile, secreção intestinale descamação epitelial (COHN et al, 2010;VAN DER WULP et al, 2013). Este colesterol é solubilizado por sais biliares em agregados macromoleculares (compostos por sais biliares, ácidos graxos, monoglicerídeos, fosfolipídios e colesterol) e conduzidos até as membranas dos enterócitos (GOODMAN, 2010).…”

Section: Lista De Siglas E Abreviaturasunclassified

“…após realizarem a digestão in vitro de extrato de uva, verificaram que os compostos fenólicos bioacessíveis exerceram efeito sobre biomarcadores do metabolismo do colesterol, sendo capazes de modular a expressão de transportador e receptor NPC1L1 e LDLr, respectivamente, reduzindo o conteúdo de LDL no plasma, já que fitoesteróis e colesterol utilizam uma via comum de absorção nos enterócitos. Neste sentido, os transportadores tem sido alvo de investigação para a inibição da absorção de lipídeos (ácidos graxos) e colesterol(SABEVA et al, 2009;TRISAT et al, 2017).…”

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Efeito de peptídeos do grão de amaranto (Amaranthus cruentus L.) sobre os mecanismos de absorção e síntese de colesterol

Menezes¹

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Dedicoà minha querida avó, in memorian. 6 7 AGRADECIMENTOS A minha família, pelo apoio, auxílio e compreensão. Agradeço ao meu marido Tiago e filhos, Rafaela e Arthur pelo carinho e força. Aos meus pais e irmãos, pela ajuda e palavras de incentivo e descontração. Ao professor José Alfredo Gomes Arêas pelos anos de ensinamento, paciência e orientação. A banca examinadora, pelas sugestões dadas no momento da defesa: Elizabeth Aparecida Ferraz da Silva Torres, Daniel Carvalho Pimenta, Marilia Cerqueira Leite Seelaender e Marisa Passarelli. Ainda à professora Elizabeth Torres pela disponibilidade do Laboratório de Bromatologia e aos pesquisadores Daniel Pimenta e Valéria Nunes, pelo auxílio com análises e ao longo do trabalho.As Doutoras Geni e Liania, pelo suporte técnico nos laboratórios, e pelas conversas do dia-a-dia.As amigas e companheiras de laboratório Cíntia Silva, RosanaSoares e Bianka Caliman, pela amizade e cooperação técnica ao longo da jornada. As minhas coordenadoras, anteriores e atual, do Hospital do Servidor PúblicoMunicipal: Fabiana Gonçalves Ferreira, Flávia Ivana Pallinger e, principalmente, a Eunice Harumi S. Sakamoto, que permitiram a execução da pesquisa.As minhas amigas e colegas nutricionistas do HSPM, pela colaboração, apoio e risadas: Fukazawa e Ana Maria de Moraes. E secretárias, Mara, Tereza e Adelma pelo auxílio. Aos amigos e colegas de laboratório: Camila Olivieri, Gustavo Fontanari, Marcelo Marques, Nara Letícia Zandonadi e Marcela Figueira, por todo o carinho, colaboração e aprendizado compartilhado. E todos aqueles que contribuíram de alguma forma para o desenvolvimento do projeto. CARLOS-MENEZES, A.C.C.C. Effect of amaranth grain peptides (Amaranthus cruentus L.) on the mechanisms of absorption and synthesis of cholesterol. 2018. ABSTRACT Introduction: Cardiovascular diseases are an important cause of death worldwide and hypercholesterolemia is directly related as an aggravating factor of this morbidity. Diet plays an important role in this process and some foods such as amaranth, especially its protein, have shown ability to lower plasma cholesterol. Studies suggest that this effect is related to peptides formed during the digestion of their protein, which play an important role in the regulation and modulation of lipid metabolism. The hypocholesterolemic effects, already observed, indicate the use of amaranth protein as a bioactive compound aimed to promoting health. Considering that the hypocholesterolemic effects of these peptides are complex and there are several hypotheses formulated, it is important to carry out studies to evaluate the interaction of peptides in the intestinal absorption of cholesterol and its genetic modulation. Objectives: To verify the effects of amaranth grain flour hydrolyzate on cholesterol uptake and ABCA1, ABCG1, NPC1L1, AMPK, HMGR and SREBP-2 genes modulation in Caco-2 intestinal cells, and modulation of ABCG8, HMGR, SREBP-2 genes and AMPK in hamster intestinal cells. Methodology: Amaranth was crushed, the created flour was defatted and its protein ...

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Vegetable Juices and Fibers Reduce Lipid Digestion or Absorption by Inhibiting Pancreatic Lipase, Cholesterol Solubility and Bile Acid Binding

Cited by 20 publications

References 27 publications

Biological Properties and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the Treatment of Obesity and Related Comorbidities

Biological Properties and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the Treatment of Obesity and Related Comorbidities

Rheological and physicochemical properties of vegetable juices and concentrates: A review

Efeito de peptídeos do grão de amaranto (Amaranthus cruentus L.) sobre os mecanismos de absorção e síntese de colesterol

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