Venous glucose and arterial lactate as biochemical predictors of mortality in clinically severely injured trauma patients—A comparison with ISS and TRISS

Sammour, Tarik; Kahokehr, Arman; Caldwell, Stuart; Hill, Andrew G.

doi:10.1016/j.injury.2008.07.032

Cited by 50 publications

(42 citation statements)

References 33 publications

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“…PPV was once again low at 13.0% and NPV was suitably high at 97.4%. [20] The highest risk of mortality was found using a cut-off value of 90 in TRISS score while with laboratory parameters, the highest risk of mortality was with serum lactate >2.6. The three parameters in predicting mortality in poly-traumatized patients were accurate, early and easy rapid predictors of mortality.…”

Section: Discussionmentioning

confidence: 84%

Venous glucose, serum lactate and base deficit as biochemical predictors of mortality in patients with polytrauma.

Saad¹

2015

Ulus Travma Acil Cerrahi Derg

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Section: Discussionmentioning

confidence: 84%

Venous glucose, serum lactate and base deficit as biochemical predictors of mortality in patients with polytrauma.

Saad¹

2015

Ulus Travma Acil Cerrahi Derg

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“…Task of trauma investigators is to develop a trauma severity indices. 2 More than 50 score systems indices for trauma patient's classification. 3 Trauma and injury severity score (TRISS), introduced in 1981, are a combination index based on Revised Trauma Score (RTS), Injury Severity Score (ISS), and patient's age.…”

Section: Introductionmentioning

confidence: 99%

Assessment of the use of TRISS scoring system in polytraumatized patients in Suez Canal university hospital, Ismailia, Egypt

et al. 2016

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“…They are complex to calculate and therefore are usually determined for purposes of audit and research. To this end, several studies have attempted to identify simpler to use (biochemical and physiological) markers that reflect physiological compromise, in order to predict morbidity and mortality [[6]–[13]].…”

Section: Introductionmentioning

confidence: 99%

Serum lactate as a predictor of early outcomes among trauma patients in Uganda

et al. 2014

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BackgroundTrauma is the leading cause of death in the developed world. Accurate assessment of severity of injuries is critical in informing treatment choices. Current models of assessing severity of injury are not without limitations. The objective of this study therefore was to determine the diagnostic accuracy of serum lactate assays in assessing injury severity and prediction of early outcomes among trauma patients.MethodsThis was a cross-sectional analytical study. Consecutive series of all eligible patients had a single venous blood sample drawn for lactate assay analysis (index test) and a concurrent Kampala Trauma Score (KTS) II value determination (reference test). Admitted patients were followed up to assess early outcomes (length of hospital stay and mortality).ResultsOut of the 502 trauma patients recruited, 108 (22%) were severely injured, 394 (78%) had non-severe injuries, and 183 were admitted. There was a significant difference between median (interquartile range (IQR)) lactate levels among the severely injured (4.3 (2.6, 6.6)) and the non-severely injured (2.4 (1.6, 3.5), p < 0.001). After a 72-h follow-up of the admitted patients, 102 (56%) were discharged, 61 (33%) remained in the hospital, 3 (2%) remained in the ICU, and 17 (3%) had died. The area under the receiver operator characteristic (ROC) curve was 0.75 for injury severity. Serum lactate ≥2.0 mmol/l had a hazard ratio of 1.10 (p < 0.001) for emergency department disposition, 4.33 (p = 0.06) for the 72-h non-discharge disposition, and 1.19 (p < 0.001) for 72-h mortality. Serum lactate ≥2.0 mmol/l at admission was useful in discriminating severe from non-severe injuries with a sensitivity of 88%, specificity of 38%, PPV of 30%, and NPV of 92%.ConclusionHyperlactatemia in an emergency trauma patient suggests a high probability of severe injury.

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Venous glucose and arterial lactate as biochemical predictors of mortality in clinically severely injured trauma patients—A comparison with ISS and TRISS

Cited by 50 publications

References 33 publications

Venous glucose, serum lactate and base deficit as biochemical predictors of mortality in patients with polytrauma.

Venous glucose, serum lactate and base deficit as biochemical predictors of mortality in patients with polytrauma.

Assessment of the use of TRISS scoring system in polytraumatized patients in Suez Canal university hospital, Ismailia, Egypt

Serum lactate as a predictor of early outcomes among trauma patients in Uganda

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