Venous Thromboembolic Disease and Abo Blood Type

Jick, Hershel; Westerholm, B; Vessey, M. P.; Lewis, GeorgeP.; Slone, Dennis; Inman, WilliamH.W.; Shapiro, Samuel; Worcester, Jane

doi:10.1016/s0140-6736(69)91955-2

Cited by 292 publications

(54 citation statements)

References 10 publications

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“…The association of ABO blood groups and diseases resulting in coagulation impairment and venous thrombus formation was first described by Jick et al (3). Most studies performed to date have generally agreed that non-OO blood group carriers have a higher risk of thrombosis than OO blood group carriers (4-7).…”

Section: Resultsmentioning

confidence: 99%

ABO Blood Groups and Genetic Risk Factors for Thrombosis in Croatian Population

et al. 2009

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Section: Resultsmentioning

confidence: 99%

ABO Blood Groups and Genetic Risk Factors for Thrombosis in Croatian Population

et al. 2009

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“…An association between ABO blood group and thrombosis risk has long been known [34,35] but the associated mechanisms are unclear [36]. Specifically, blood group non-O has been associated with increased risk for venous thrombosis [37,38].…”

Section: Discussionmentioning

confidence: 99%

The Status of Thrombophilic Defects and Non-O Blood Group as Risk Factors for Gestational Vascular Complications among Tunisian Women

Klai¹,

Fekih-Mrissa²,

Rachdi

et al. 2010

Acta Haematol

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Aims: Our objectives were to assess inherited thrombophilia and non-O blood group for the risk of gestational vascular complications among the Tunisian population. Methods: This study comprised 203 test subjects with adverse pregnancy outcomes including recurrent pregnancy loss, intra-uterine growth retardation, pre-eclampsia and placental abruption. Each subgroup was matched with 100 controls and analyzed separately. All patients were evaluated for factor V Leiden, factor II G20210A mutations and for non-O blood group. Protein S, protein C and antithrombin levels were determined and deficiencies noted. Results: The factor V Leiden mutation, non-O blood group and protein C deficiency had the highest incidences among patients both as a whole and in the 4 subgroups. The factor II G20210A mutation, protein S and antithrombin deficiencies were not statistically significant risk factors. Conclusion: Our results provide evidence for a significant association between the factor V mutation and placental abruption. Furthermore, we found that this and the non-O blood group independently increased the risk for intra-uterine growth retardation in our population.

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“…High Factor VIII Levels In 1969, Jick et al 105 reported that blood group non-O is associated with an increased risk of venous thrombosis. Today, we know that individuals with blood group non-O have higher levels of vWF and factor VIII than do those with blood group O.…”

Section: Venous Thrombosismentioning

confidence: 99%