2002
DOI: 10.1590/s0102-35862002000600011
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Ventilação líquida: revisão da literatura

Abstract: Atualmente, novas alternativas de ventilação têm sido estudadas em quadros de insuficiência respiratória, com o objetivo de melhorar a oxigenação e minimizar a agressão ao parênquima pulmonar. A utilização de perfluorocarbonos líquidos administrados diretamente na via aérea vem sendo ostensivamente estudada em modelos de lesão pulmonar e em alguns ensaios clínicos, demonstrando bons resultados com relação à troca gasosa, mecânica ventilatória e propriedades antiinflamatórias. Os PFCs são substâncias que possue… Show more

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Cited by 1 publication
(2 citation statements)
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References 83 publications
(106 reference statements)
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“…The rationale for using PFC is mostly to protect the lungs once lung injury has been established [ 19 , 23 , 26 , 40 ]. Based on such observations and the results of the present study, which suggests that the PFC can also be used before the onset of severe lung injury, lung transplantation can be a suitable model in which the PFC can provide both graft protection and IR injury reduction.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The rationale for using PFC is mostly to protect the lungs once lung injury has been established [ 19 , 23 , 26 , 40 ]. Based on such observations and the results of the present study, which suggests that the PFC can also be used before the onset of severe lung injury, lung transplantation can be a suitable model in which the PFC can provide both graft protection and IR injury reduction.…”
Section: Discussionmentioning
confidence: 99%
“…Liquid perfluorocarbons (PFCs) administered endobronchially have been used in different models of lung injury [ 22 , 23 ], primarily as an alternative method of lung ventilation, known as partial liquid ventilation [ 19 ]. PFCs wash out alveoli debris, recruit collapsed alveoli, improve gas exchange, protect pulmonary architecture and have anti-inflammatory and antioxidant properties [ 24 , 25 ].…”
Section: Introductionmentioning
confidence: 99%