Vernarbende Tinea profunda des Mons pubis durch Trichophyton verrucosum

Grunewald, Sonja; Paasch, Uwe; Gräser, Yvonne; Glander, H.‐J.; Simon, J. C.; Nenoff, P.

doi:10.1007/s00105-005-1066-7

Cited by 19 publications

(10 citation statements)

References 6 publications

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“…In the patients presented here a longer treatment period was necessary (mean 5 weeks). In the recent literature, an example of prolonged therapy was described in a case report of a female veterinary student with a severe inflammatory fungal infection of the pubic area after working in a cattle farm 20. In that case, the pathogen was identified as T. verrucosum , also a zoophilic dermatophyte.…”

Section: Discussionmentioning

confidence: 99%

Tinea genitalis: a new entity of sexually transmitted infection? Case series and review of the literature

et al. 2015

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ObjectiveInvestigation on recent cases of tinea genitalis after travelling to South East Asia.MethodsPatients with tinea in the genital region, which emerged after sex in South East Asia, underwent further assessment including microscopy, cultures and DNA analyses.ResultsThe case series includes seven patients. In six patients, Trichophyton interdigitale (former Trichophyton mentagrophytes) was detected. Three patients suffered from a severe inflammatory reaction of the soft tissue and two of them needed hospitalisation due to severe pain. In four patients, cicatrising healing was noticed. Five patients were declared incapacitated for work.ConclusionsSexual activity should be considered as a potentially important and previously underappreciated means of transmission of T. interdigitale. To avoid irreversible scarring alopecia, prompt initiation of antifungal treatment is essential and adequate isolation and identification of the pathogen is mandatory.

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Section: Discussionmentioning

confidence: 99%

Tinea genitalis: a new entity of sexually transmitted infection? Case series and review of the literature

et al. 2015

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“…Die Möglich-keit einer Transmission der genitalen Infektion über sexuelle Kontakte muss bedacht werden [13]. Nicht zuletzt durch die meist zu spät initiierte orale antimykotische Behandlung kann es zu narbiger Abheilung im Sinne einer Pseudopelade Brocq kommen [7].…”

Section: Therapieunclassified

Tinea im Genitalbereich

Ginter‐Hanselmayer

Nenoff²,

Kurrat

et al. 2016

Hautarzt

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“…Although several secreted proteases from dermatophytes have been obtained as recombinant proteins, no T. verrucosum-secreted proteases are currently available in recombinant form. In spite of their different ecologies, the genome of T. rubrum (21) proved to be most closely related to the genomes of T. verrucosum and Arthroderma benhamiae, two phylogenetically closely related dermatophytes that induce highly inflammatory cutaneous infections in humans (22,23). In addition, most Trichophyton species revealed similar secreted protein profiles (24).…”

Section: Methodsmentioning

confidence: 99%

Development of an Enzyme-Linked Immunosorbent Assay for Serodiagnosis of Ringworm Infection in Cattle

Bagut

Cambier

Heinen

et al. 2013

Clin Vaccine Immunol

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The aim of this study was to develop an in-house enzyme-linked immunosorbent assay (ELISA) for the serological diagnosis of ringworm infection in cattle. We used available recombinant forms of Trichophyton rubrum dipeptidyl peptidase V (TruDppV) and T. rubrum leucin aminopeptidase 2 (TruLap2), which are 98% identical to Trichophyton verrucosum orthologues. Field serum samples from 135 cattle with ringworm infection, as confirmed by direct microscopy, fluorescence microscopy, and PCR, and from 55 cattle without any apparent skin lesions or history of ringworm infection that served as negative controls were used. Sensitivities, specificities, and positive and negative predictive values were determined to evaluate the diagnostic value of our ELISA. Overall, the ELISAs based on recombinant TruDppV and TruLap2 discriminated well between infected animals and healthy controls. Highly significant differences (P < 0.0001, Mann-Whitney U test) were noted between optical density values obtained when sera from infected versus control cattle were tested. The ELISA developed for the detection of specific antibodies against DppV gave 89.6% sensitivity, 92.7% specificity, a 96.8% positive predictive value, and a 78.4% negative predictive value. The recombinant TruLap2-based ELISA displayed 88.1% sensitivity, 90.9% specificity, a 95.9% positive predictive value, and a 75.7% negative predictive value. To the best of our knowledge, this is the first ELISA based on recombinant antigens for assessing immune responses to ringworm infection in cattle; it is particularly suitable for epidemiological studies and also for the evaluation of vaccines and/or vaccination procedures.

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Vernarbende Tinea profunda des Mons pubis durch Trichophyton verrucosum

Cited by 19 publications

References 6 publications

Tinea genitalis: a new entity of sexually transmitted infection? Case series and review of the literature

Tinea genitalis: a new entity of sexually transmitted infection? Case series and review of the literature

Tinea im Genitalbereich

Development of an Enzyme-Linked Immunosorbent Assay for Serodiagnosis of Ringworm Infection in Cattle

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