Versuche über die Bildung von Vitamin durch Bakterien

Refection, a Transmissible Change in the Intestinal Content, enabling Rats to grow and thrive without Vitamin B in the Food

“…Other researches deal with feeding of bacteria to young rats deprived of vitamin B. Cultures of B. coli and other faeces bacteria, of lactic acid bacteria, of B. Friedlaender and of B. subtilis etc. did not lessen the deficiency symptoms of the rats (Woilman and Vagliano (1922), Damon (1923), Bieling (1925)). A few species, however, when fed in big amounts, are reported to induce growth in rats deprived of vitamin B. Extracts of B. typhoMu have been stated to possess this property (Pacini and Russell, 1918), but Damon (1921) obtained only negative results when feeding B. paratyphosu.…”

“…Previous investigations dealing with the possible production of vitamin B by bacteria are of interest in this connection. Several papers dealing with the feeding of cultures of Bacillus coli and other common intestinal bacteria or moulds to rice-fed pigeons with polyneuritic symptoms record neither recovery nor diminution of symptoms (Cooper (1914), Woilman (1921), Eijkman, van Hoogenhuijze and Derks (1922), Weill, Arloing and Dufourt (1922), Scheunert and Schieblich (1922), Bieling (1925)). Scheunert and Schieblich (1923) found later that large amounts of B. vulgatus lessened polyneuritic symptoms in pigeons, but the content of this vitamin in masses of this bacterium was less than in yeast.…”