Vertical patellar dislocation in a 25-year-old female

Gragossian, Alin; Varacallo, Matthew; Misthal, Sara

doi:10.1016/j.visj.2018.07.037

Cited by 2 publications

(4 citation statements)

References 1 publication

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“…A previously reported radial nerve injury model was adapted to assess the functional recovery of xenogeneic and autologous nerve transplant recipients 42 . Radial nerve injury proximal to the elbow results in a loss of wrist extension function, or “wrist drop,” loss of forearm muscle tonality, and digital extension due to motor denervation of the extensor carpi radialis longus and extensor carpi radialis brevis muscles 43,44 . Wrist extension testing and evaluation were performed monthly.…”

Section: Methodsmentioning

confidence: 99%

Large‐gap peripheral nerve repair using xenogeneic transplants in rhesus macaques

Holzer

Chang²,

Rogers³

et al. 2023

Xenotransplantation

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Surgical intervention is required to successfully treat severe, large-gap (≥4 cm) peripheral nerve injuries. However, all existing treatments have shortcomings and an alternative to the use of autologous nerves is needed. Human andporcine nerves are physiologically similar, with comparable dimensions and architecture, presence and distribution of Schwann cells, and conserved features of the extracellular matrix (ECM). We report the repair of fully transected radial nerves in 10 Rhesus Macaques using viable, whole sciatic nerve from genetically engineered (GalT-KO), designated pathogen free (DPF) porcine donors. This resulted in the regeneration of the transected nerve, recovery of wrist extension function, distal muscle reinnervation, and recovery of nerve conduction velocities and compound muscle action potentials statistically equivalent to autologous controls. We also demonstrate the absence of immune rejection, systemic porcine cell migration, and detectable residual porcine material. Our ndings support the safety and e cacy of viable porcine nerve transplants, suggest the interchangeable therapeutic use of crossspecies cells, and highlight the broader clinical potential of xenotransplantation.

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Section: Methodsmentioning

confidence: 99%

Large‐gap peripheral nerve repair using xenogeneic transplants in rhesus macaques

Holzer

Chang²,

Rogers³

et al. 2023

Xenotransplantation

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“…1 Its impairment can lead to debilitating consequences, including a significant weakening of grip strength and substantial challenges to the affected individual's daily life and occupational activities. 2,3 The global incidence of radial nerve palsy is not well-documented, but it is known to be a common peripheral nerve injury, often resulting from fractures, penetrating injuries, or prolonged pressure on the nerve. 4,5 Certain conditions such as COVID-19 have also been associated with nerve dysfunctions, including ulnar nerve palsy, which may have implications for radial nerve palsy.…”

Section: Introductionmentioning

confidence: 99%

“…In severe cases, the condition can lead to disability. 3 Moreover, complications such as chronic pain can significantly affect the quality of life of individuals with radial nerve palsy. 3,10 The standard treatment for radial nerve palsy is tendon transfer, a surgical procedure that restores function by rerouting tendons from their original attachments to new locations.…”

Section: Introductionmentioning

confidence: 99%

“…3 Moreover, complications such as chronic pain can significantly affect the quality of life of individuals with radial nerve palsy. 3,10 The standard treatment for radial nerve palsy is tendon transfer, a surgical procedure that restores function by rerouting tendons from their original attachments to new locations. However, the optimal choice of tendon transfers for radial nerve palsy remains a subject of ongoing debate among surgeons.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of radial nerve palsy treatment: tendon transfer with the flexor carpi radialis combination

Sarker,

Hossain,

Siddique

et al. 2023

Int Surg J

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Introduction: Radial nerve palsy, a common peripheral nerve injury, significantly impacts the quality of life of affected individuals. The standard treatment is tendon transfer, but the optimal choice of tendon transfers remains a subject of ongoing debate. This study aimed to evaluate the treatment of radial nerve palsy through tendon transfer with the flexor carpi radialis combination in a Bangladeshi population. Methods: This observational study was conducted over 18 weeks at the Department of Orthopedic Surgery of 3 medical college hospitals in Bangladesh. Forty adult patients with radial nerve palsy were selected based on specific inclusion criteria. Participants were evaluated preoperatively and postoperatively using the Disabilities of the Arm, Shoulder, and Hand (DASH) score. Complications were also recorded. Results: The majority of participants were male (77.5%) and had right-sided injuries (72.5%). The most common cause of injury was humerus shaft injury (55.0%). The most common site of injury was middle third of the humerus shaft (67.50%). Postoperatively, 85.0% achieved an "Excellent" grade. Complications were minimal, with 90% of participants experiencing no complications. Conclusions: Tendon transfer with the flexor carpi radialis combination appears to be an effective treatment for radial nerve palsy, with significant improvements in DASH scores postoperatively and minimal complications. Further research is needed to confirm these findings and compare the effectiveness of this treatment with other tendon transfer combinations.

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Vertical patellar dislocation in a 25-year-old female

Cited by 2 publications

References 1 publication

Large‐gap peripheral nerve repair using xenogeneic transplants in rhesus macaques

Large‐gap peripheral nerve repair using xenogeneic transplants in rhesus macaques

Evaluation of radial nerve palsy treatment: tendon transfer with the flexor carpi radialis combination

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