Vertical transmission of fatal Rift Valley fever in a newborn

Arishi, Haider M.; Aqeel, Ali; Hazmi, Mohamed Mohamed Al

doi:10.1179/146532806x120363

Cited by 70 publications

(52 citation statements)

References 2 publications

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“…During the outbreak, a serious case of vertical transmission from mother to the baby was documented [41], similar to a previously reported case in Saudi Arabia in 2000 [42]. Many maternal deaths were observed in Central Sudan during the RVF outbreak [41], consistent with the claims recently made about the burden of emerging zoonotic infectious disease among women in general, and pregnant women in particular [43].…”

Section: Risk Factors For Severe Rvfv Infectionsupporting

confidence: 85%

The 2007 Rift Valley Fever Outbreak in Sudan

et al. 2011

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Rift Valley fever (RVF) is a neglected, emerging, mosquito-borne disease with severe negative impact on human and animal health and economy. RVF is caused by RVF virus (RVFV) affecting humans and a wide range of animals. The virus is transmitted through bites from mosquitoes and exposure to viremic blood, body fluids, or tissues of infected animals. During 2007 a large RVF outbreak occurred in Sudan with a total of 747 confirmed human cases including 230 deaths (case fatality 30.8%); although it has been estimated 75,000 were infected. It was most severe in White Nile, El Gezira, and Sennar states near to the White Nile and the Blue Nile Rivers. Notably, RVF was not demonstrated in livestock until after the human cases appeared and unfortunately, there are no records or reports of the number of affected animals or deaths. Ideally, animals should serve as sentinels to prevent loss of human life, but the situation here was reversed. Animal contact seemed to be the most dominant risk factor followed by animal products and mosquito bites. The Sudan outbreak followed an unusually heavy rainfall in the country with severe flooding and previous studies on RVF in Sudan suggest that RVFV is endemic in parts of Sudan. An RVF outbreak results in human disease, but also large economic loss with an impact beyond the immediate influence on the directly affected agricultural producers. The outbreak emphasizes the need for collaboration between veterinary and health authorities, entomologists, environmental specialists, and biologists, as the best strategy towards the prevention and control of RVF.

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Section: Risk Factors For Severe Rvfv Infectionsupporting

confidence: 85%

The 2007 Rift Valley Fever Outbreak in Sudan

et al. 2011

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“…A previous case study from 2006 had suggested that RVFV can spread by vertical transmission from infected mothers to their unborn children [33]. During the recent 2007-2008 Sudanese outbreak, preterm labor due to acute RVF disease was also found to result in delivery of an anti-RVFV IgM positive baby with skin rash and hepatosplenomegaly, again suggesting that vertical transmission of RVFV probably does occur among humans [34].…”

Section: Human Rvf Diseasementioning

confidence: 99%

Advances in Rift Valley fever research: insights for disease prevention

LaBeaud¹,

Kazura²,

King

2010

Current Opinion in Infectious Diseases

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Purpose of review The purpose of the study was to review recent research on Rift Valley fever virus (RVFV) infection, encompassing four main areas: epidemiology and outbreak prediction, viral pathogenesis, human diagnostics and therapeutics, and vaccine and therapeutic candidates. Recent findings RVFV continues to extend its range in Africa and the Middle East. Better definition of RVFV-related clinical syndromes and human risk factors for severe disease, combined with early-warning systems based on remote-sensing, simplified rapid diagnostics, and tele-epidemiology, hold promise for earlier deployment of effective outbreak control measures. Advances in understanding of viral replication pathways and host cell-related pathogenesis suggest means for antiviral therapeutics and for more effective vaccination strategies based on genetically engineered virus strains or subunit vaccines. Summary RVFV is a significant health and economic burden in many areas of Africa, and remains a serious threat to other parts of the world. Development of more effective methods for RVFV outbreak prevention and control remains a global health priority.

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“…35 The virus has not shown direct human-to-human transmission, and there have been only a few documented cases of vertical transmission. 36–38 …”

Section: Epidemiologymentioning

confidence: 99%

“…28,66,67 Even though isolated cases of vertical transmission have been documented, 36–38 there appears to be no increase in apparent miscarriage in pregnant women. There is also no documented human-to-human transmission; infection of people appears to be limited to either mosquito bites or exposure to high titer animal tissues.…”

Section: Clinical Presentationmentioning

confidence: 99%

Rift Valley Fever

Hartman

2017

Clinics in Laboratory Medicine

103

134

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SYNOPSIS Rift Valley Fever (RVF) is a severe veterinary disease of livestock that also causes moderate to severe illness in people. The life cycle of RVF is complex and involves mosquitoes, livestock, people, and the environment. RVF virus (RVFV) is transmitted from either mosquitoes or farm animals to humans, but cannot be transmitted from person to person. People can develop different diseases following infection: febrile illness, ocular disease, hemorrhagic fever, or encephalitis. There is a significant risk for emergence of RVF into new locations, which would affect human health and livestock industries.

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Vertical transmission of fatal Rift Valley fever in a newborn

Cited by 70 publications

References 2 publications

The 2007 Rift Valley Fever Outbreak in Sudan

The 2007 Rift Valley Fever Outbreak in Sudan

Advances in Rift Valley fever research: insights for disease prevention

Rift Valley Fever

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