Vesicular prurigo pigmentosa cured by minocycline

Matsumoto, Chihiro; Kinoshita, Masako; Baba, Shunichi; Suzuki, Hiroyuki; Kanematsu, S; Kanematsu, Nobutake

doi:10.1046/j.1468-3083.2001.00296.x

Cited by 11 publications

(12 citation statements)

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“…PP has been treated by doxycycline, minocycline and dapsone to good effect; minocycline appears to be more effective than doxycycline and dapsone due to its rapid resolution and fewer adverse side‐effects in treating PP . Indeed, Gironi confirmed that 2 weeks of minocycline treatment can significantly decrease PP skin lesions …”

Section: Discussionmentioning

confidence: 99%

Prurigo pigmentosa: a clinical and histopathological study of nine Chinese cases

Zeng

Cui

2016

Acad Dermatol Venereol

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Section: Discussionmentioning

confidence: 99%

Prurigo pigmentosa: a clinical and histopathological study of nine Chinese cases

Zeng

Cui

2016

Acad Dermatol Venereol

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“…A variety of agents are used in the treatment of PP, the most effective of which are oral antibiotics such as minocycline, doxycycline and sulfonamides such as dapsone . Recently, minocycline has been preferred to dapsone because it has fewer side‐effects and results in a longer remission . The therapeutic effects of minocycline and doxycycline are thought to be due to their anti‐inflammatory effects.…”

Section: Discussionmentioning

confidence: 99%

Prurigo pigmentosa: Clinicopathological study and analysis of 50 cases in Korea

Kim

Chung

Chang

et al. 2012

The Journal of Dermatology

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Prurigo pigmentosa is a recurrent dermatosis with severe pruritus and several peculiar clinical features. Its exact etiology and pathogenesis are unclear. The aim of this study was to investigate the clinical features and chronological changes in the histopathology of prurigo pigmentosa in Korean patients and to assess the etiology of this condition. We reviewed the medical records, clinical photographs and biopsy specimens from 50 patients diagnosed with prurigo pigmentosa. Mean age at diagnosis was 23.7 years (range, 15-61 years). Prurigo pigmentosa started as urticarial papules or plaques, changing first to papulovesicles and then to reticulated brownish macules. The most frequent sites were the back and chest, especially depressed areas such as the central back and inter-mammary area. Dietary change was suspected as a cause of prurigo pigmentosa in 17 patients. Histopathologically, early-stage lesions had dermatitis herpetiformis-like features; fully-developed lesions displayed impetigo-like or acute, generalized, exanthematous, pustulosis-like features; and late lesions presented with post-inflammatory hyperpigmentation-like features. Oral minocycline, with or without dapsone, was effective in inhibiting the appearance of new lesions, but did not prevent recurrence. Prurigo pigmentosa is not rare in Korea, is apparently associated with dietary modification and preferentially involves the depressed regions of the trunk.

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“…663 It is uncommon in the Western world, although over 50 cases have now been reported. 666,667,673 Doxycycline, macrolide antibiotics, isotretinoin, 674 and dapsone have also been used to treat this condition. [668][669][670] Its association with Helicobacter infection may have been fortuitous.…”

Section: Dowling-degos Diseasementioning

confidence: 99%