Vestibular nerve projection to the cerebral cortex of the Rhesus monkey

Fredrickson, John M.; Scheid, P.; Figge, U; Kornhuber, H. H.

doi:10.1007/bf00234777

Cited by 292 publications

(55 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These somatosensory and visuospatial fields of the parietal lobe converge around the region of the intraparietal sulcus. The tip of the intraparietal sulcus, which has been activated in the mental rotation task, receives a major vestibular input (29,30). In the monkey, it has been shown that neuronal activity within the intraparietal sulcus converts the retinal coordinates of visual stimuli into a body-centered frame of reference (28).…”

Section: Discussionmentioning

confidence: 99%

Neural correlates of mental transformations of the body-in-space.

Bonda

Petrides

Frey

et al. 1995

Proc. Natl. Acad. Sci. U.S.A.

299

163

View full text Add to dashboard Cite

Regional cerebral blood flow was measured with positron emission tomography in human subjects during the performance of a task requiring mental rotation of their hand and a perceptually equivalent control task that did not require such a process. Comparison of the distribution of cerebral activity between these conditions demonstrated significant blood flow increases in the superior parietal cortex, the intraparietal sulcus, and the adjacent rostralmost part of the inferior parietal lobule. These findings demonstrated that, in the human brain, there is a specific system of parietal areas that are involved in mental transformations of the body-inspace.Patients with lesions of the parietal region of the brain exhibit various disturbances of body knowledge (1-3). Large parietal lesions give rise to classical syndromes such as right-left disorientation (1-3) and autotopagnosia, a deficit in localizing body parts in relation to the whole body (4-6). These syndromes are most often associated with lesions of the left hemisphere. Similarly, epileptic manifestations that accompany parietal-lobe tumors can result in disturbances of the body image, such as absence or displacement of a part of the body, transformation of a limb into a mechanical object, the phantom appearance of a third limb, and the personification of a body part (3). These intriguing phenomena are assumed to result from an impairment in the "body schema" (1-3) that traditional neurological thinking ascribed to the posterior parietal cortex (7).There is some evidence, based on single-cell recording studies with nonhuman primates, that neuronal activity in the cortex of the superior parietal lobule (area PE) and its rostrally adjacent cortex surrounding the anteriormost part of the intraparietal sulcus (area PF) codes the position and orientation of body parts in relation to each other (8, 9). We hypothesize that these areas, within the broader neural network in which they are embedded, are the essential components underlying body awareness.This neural system constantly receives information about changing states from the skin and the joints and builds, on this basis, a dynamic and plastic mental representation of the body-in-space. The body is thus placed in a continuous interactive relation with the external world. This dynamic interaction allows for the simulation of continuous spatiotemporal trajectories of body motion and specifies how one's future posture causally depends on one's current posture.

show abstract

Section: Discussionmentioning

confidence: 99%

Neural correlates of mental transformations of the body-in-space.

Bonda

Petrides

Frey

et al. 1995

Proc. Natl. Acad. Sci. U.S.A.

299

163

View full text Add to dashboard Cite

show abstract

“…Whether the pulvinar units we recorded could supply these parietal and temporal areas is presently unknown. Finally, vestibular responses have also been reported in the fron- tal eye fields (FEFs) (Fukushima et al, 2000;Ebata et al, 2004) and premotor/motor cortex (Fredrickson et al, 1966;BoisacqSchepens and Hanus, 1972;Guldin et al, 1992). The numerous vestibular units in VL, which are supplied by both the VN and CN, are well positioned to transfer vestibular signals to premotor/ motor cortex.…”

Section: Vestibular Cortexmentioning

confidence: 99%

“…Some cortical vestibular signals may originate through corticocortical connections Stanton et al, 1995;Lewis and Van Essen, 2000), but ultimately these signals must reach cortex via the thalamus. Among these vestibular cortical regions are portions of the retroinsular cortex [parieto-insular vestibular cortex (PIVC)] (Grüsser et al, 1990a,b), and the neck regions of area 3a of primary somatosensory cortex (3aV) (Fredrickson et al, 1966;Schwarz and Fredrickson, 1971a,b;Odkvist et al, 1974;Büttner and Buettner, 1978;Guldin et al, 1992). In squirrel monkeys, 3aV receives projections from rostral and dorsal VPL (designated VPLo and VPLs by Akbarian et al, 1992), whereas PIVC receives its main thalamic input from caudal VPL and from the pulvinar .…”

Section: Vestibular Cortexmentioning

confidence: 99%

“…Other portions of parietal and temporal cortex showing vestibular activity include the anterior tip of the intraparietal sulcus (area 2v) (Büttner and Buettner 1978;Fredrickson et al, 1966;Schwarz and Fredrickson 1971a,b), the medial superior temporal area (Page and Duffy, 2003;Gu et al, 2006Gu et al, , 2007, and the ventral intraparietal area (Bremmer et al, 2002;Klam and Graf, 2003;Chen et al, 2007). Whether the pulvinar units we recorded could supply these parietal and temporal areas is presently unknown.…”

Section: Vestibular Cortexmentioning

confidence: 99%

See 1 more Smart Citation

Vestibular Signals in Primate Thalamus: Properties and Origins

Hui¹,

May²,

Dickman³

et al. 2007

J. Neurosci.

131

162

View full text Add to dashboard Cite

“…In somatosensory cortex vestibular stimulations activate the anterior tip of the intraparietal sulcus [50,85,94,112] and the primary somatosensory cortex, near the central sulcus [20,47,50,100]. These regions represent probably the human homologue of two monkey areas that have been found to integrate vestibular and somatosensory information: area 2v, at the base of the intraparietal sulcus [53] and area 3av at the hand/arm and neck/trunk representations [66,96]. Another vestibular area has been described in the posterior parietal cortex and was activated during caloric and galvanic vestibular stimulations particularly in the intraparietal sulcus [50,85,112] and superior parietal lobule [118].…”

Section: The Vestibular Cortexmentioning

confidence: 99%

Body ownership and embodiment: Vestibular and multisensory mechanisms

Lopez

Halje

Blanke

2008

Neurophysiologie Clinique/Clinical Neurophysiology

236

163

View full text Add to dashboard Cite

Summary Body ownership and embodiment are two fundamental mechanisms of selfconsciousness. The present article reviews neurological data about paroxysmal illusions during which body ownership and embodiment are affected differentially: autoscopic phenomena (out-of-body experience, heautoscopy, autoscopic hallucination, feeling-of-a-presence) and the room tilt illusion. We suggest that autoscopic phenomena and room tilt illusion are related to different types of failures to integrate body-related information (vestibular, proprioceptive and tactile cues) in addition to a mismatch between vestibular and visual references. In these patients, altered body ownership and embodiment has been shown to occur due to pathological activity at the temporoparietal junction and other vestibular-related areas arguing for a key importance of vestibular processing. We also review the possibilities of manipulating body ownership and embodiment in healthy subjects through exposition to weightlessness as well as caloric and galvanic stimulation of the peripheral vestibular apparatus. In healthy subjects, disturbed self-processing might be related to interference of vestibular stimulation with vestibular cortex leading to disintegration of bodily information and altered body ownership and embodiment. We finally propose a differential contribution of the vestibular cortical areas to the different forms of altered body ownership and embodiment. Résumé L'attribution du corps propre et de ses éléments constitutifs (body ownership), ainsi que le sentiment d'incarnation (embodiment) -le fait d'habiter ce corps, d'être localisé dans les limites physiques de ce corps -, sont deux éléments fondamentaux de la conscience de soi. Nous faisons ici la synthèse de données issues de la neurologie montrant que des manifestations paroxystiques telles que les phénomènes autoscopiques (expérience de sortie du corps, héautoscopie, hallucination autoscopique, sensation de présence) et l'illusion de bascule de l'environnement (room tilt illusion) se caractérisent par une atteinte différentielle des mécanismes d'attribution du corps propre et du sentiment d'incarnation. Nous faisons l'hypothèse que les différents phénomènes autoscopiques et l'illusion de bascule de l'environnement se caractérisent par différents patrons de déficits d'intégration des informations sensorielles corporelles (informations visuelles, musculaires proprioceptives et tactiles) combinés à une perte de cohérence entre les références visuelles et vestibulaires. Chez les patients souffrant de phénomènes autoscopiques, les déficits d'attribution du corps propre et du sentiment d'incarnation ont été liés à un dysfonctionnement au niveau de la jonction temporopariétale et d'autres régions corticales recevant des informations vestibulaires, suggérant une contribution importante des afférences vestibulaires dans les mécanismes de la conscience de soi. Nous rapportons également des données de la littérature recueillies chez des sujets sains suggérant la possibilité de manipuler l'attribution ...

show abstract

Vestibular nerve projection to the cerebral cortex of the Rhesus monkey

Cited by 292 publications

References 6 publications

Neural correlates of mental transformations of the body-in-space.

Neural correlates of mental transformations of the body-in-space.

Vestibular Signals in Primate Thalamus: Properties and Origins

Body ownership and embodiment: Vestibular and multisensory mechanisms

Contact Info

Product

Resources

About