Vestibular stimulation does not diminish the desire for amputation

Lenggenhager, Bigna; Hilti, Leonie; Palla, Antonio; Macauda, Gianluca; Brugger, Peter

doi:10.1016/j.cortex.2014.02.004

Cited by 33 publications

(21 citation statements)

References 11 publications

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“…While Anorexia Nervosa has not yet been experimentally assessed and linked to vestibular stimulation, other mental disorders—outlined below—have been investigated. However, on this note, it is important to point out that a recent study that assessed the effect of CVS in participants suffering from body identity integrity disorder (BIID) was not able to significantly reduce the estrangement of the affected limb(s) (Lenggenhager et al, 2014). Against the background of publication bias, negative findings are informative and clearly indicate the need for well-controlled studies with sufficient sample size.…”

Section: Body Representationmentioning

confidence: 99%

Spatial cognition, body representation and affective processes: the role of vestibular information beyond ocular reflexes and control of posture

Mast

Preuss

Hartmann

et al. 2014

Front. Integr. Neurosci.

107

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A growing number of studies in humans demonstrate the involvement of vestibular information in tasks that are seemingly remote from well-known functions such as space constancy or postural control. In this review article we point out three emerging streams of research highlighting the importance of vestibular input: (1) Spatial Cognition: Modulation of vestibular signals can induce specific changes in spatial cognitive tasks like mental imagery and the processing of numbers. This has been shown in studies manipulating body orientation (changing the input from the otoliths), body rotation (changing the input from the semicircular canals), in clinical findings with vestibular patients, and in studies carried out in microgravity. There is also an effect in the reverse direction; top-down processes can affect perception of vestibular stimuli. (2) Body Representation: Numerous studies demonstrate that vestibular stimulation changes the representation of body parts, and sensitivity to tactile input or pain. Thus, the vestibular system plays an integral role in multisensory coordination of body representation. (3) Affective Processes and Disorders: Studies in psychiatric patients and patients with a vestibular disorder report a high comorbidity of vestibular dysfunctions and psychiatric symptoms. Recent studies investigated the beneficial effect of vestibular stimulation on psychiatric disorders, and how vestibular input can change mood and affect. These three emerging streams of research in vestibular science are—at least in part—associated with different neuronal core mechanisms. Spatial transformations draw on parietal areas, body representation is associated with somatosensory areas, and affective processes involve insular and cingulate cortices, all of which receive vestibular input. Even though a wide range of different vestibular cortical projection areas has been ascertained, their functionality still is scarcely understood.

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Section: Body Representationmentioning

confidence: 99%

Spatial cognition, body representation and affective processes: the role of vestibular information beyond ocular reflexes and control of posture

Mast

Preuss

Hartmann

et al. 2014

Front. Integr. Neurosci.

107

View full text Add to dashboard Cite

show abstract

“…While a preliminary exploration of pain perception in two individuals with amputation desire showed increased SCRs for noxious stimuli contacting the unwanted limb (Brang, McGeoch, & Ramachandran, 2008), no data on pain anticipation are available yet. A conceptual similarity between somatoparaphrenia and the disturbance of 'overcompleteness' has been previously proposed based on the disownership sensations associated with both conditions (Berti, 2013;Brang et al, 2008;Lenggenhager, Hilti, Palla, Macauda, & Brugger, 2014). However the two disorders also have a fundamental theoretical difference.…”

mentioning

confidence: 98%

Body ownership: When feeling and knowing diverge

Romano

Sedda

Brugger

et al. 2015

Consciousness and Cognition

Self Cite

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Individuals with the peculiar disturbance of 'overcompleteness' experience an intense desire to amputate one of their healthy limbs, describing a sense of disownership for it (Body Integrity Identity Disorder -BIID). This condition is similar to somatoparaphrenia, the acquired delusion that one's own limb belongs to someone else. In ten individuals with BIID, we measured skin conductance response to noxious stimuli, delivered to the accepted and non-accepted limb, touching the body part or simulating the contact (stimuli approach the body without contacting it), hypothesizing that these individuals have responses like somatoparaphrenic patients, who previously showed reduced pain anticipation, when the threat was directed to the disowned limb. We found reduced anticipatory response to stimuli approaching, but not contacting, the unwanted limb. Conversely, stimuli contacting the non-accepted body-part, induced stronger SCR than those contacting the healthy parts, suggesting that feeling of ownership is critically related to a proper processing of incoming threats. AbstractPersons with peculiar disturbance of 'overcompleteness' experience an intense desire to amputate

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“…Finally, a recent study disconfirmed the hypothesis of Ramachandran and McGeoch: symptoms related to the desire for amputation did not disappear after CVS: the converse of what happens with somatoparaphrenic patients 32. These results seem to preclude this condition being as simple as a “developmental somatoparahrenia”9 and cast new doubt on a pure neurologic etiology, despite the promising results of the other imaging studies.…”

Section: Etiological Hypothesesmentioning

confidence: 94%

Apotemnophilia, body integrity identity disorder or xenomelia? Psychiatric and neurologic etiologies face each other

Sedda

Bottini

2014

NDT

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This review summarizes the available studies of a rare condition in which individuals seek the amputation of a healthy limb or desire to be paraplegic. Since 1977, case reports and group studies have been produced, trying to understand the cause of this unusual desire. The main etiological hypotheses are presented, from the psychological/psychiatric to the most recent neurologic explanation. The paradigms adopted and the clinical features are compared across studies and analyzed in detail. Finally, future directions and ethical implications are discussed. A proposal is made to adopt a multidisciplinary approach that comprises state-of-the-art technologies and a variety of theoretical models, including both body representation and psychological and sexual components.

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Vestibular stimulation does not diminish the desire for amputation

Abstract: Word count: 992Number of tables: 1

Cited by 33 publications

References 11 publications

Spatial cognition, body representation and affective processes: the role of vestibular information beyond ocular reflexes and control of posture

Spatial cognition, body representation and affective processes: the role of vestibular information beyond ocular reflexes and control of posture

Body ownership: When feeling and knowing diverge

Apotemnophilia, body integrity identity disorder or xenomelia? Psychiatric and neurologic etiologies face each other

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