Vibrational Spectroscopy Applications in Drugs Analysis

Bunaciu, Andrei A.; Aboul‐Enein, Hassan Y.

doi:10.1016/b978-0-12-409547-2.12214-0

Cited by 17 publications

(10 citation statements)

References 25 publications

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“…They have been employed in many fields, such as the agricultural, food, and pharmaceutical [ 28 , 29 ]. The most frequently used are mid-infrared (MIR), near-infrared (NIR), and Raman spectroscopy [ 32 ] Figure 2 shows the NIR, MIR and Raman spectra of Argan oil and other vegetable oils, such as corn, rapeseed, sunflower and peanut oil. The data from these techniques need to be submitted to chemometric tools for data trends analysis.…”

Section: Argan Oil Quality Control and Authentication Assessmentmentioning

confidence: 99%

Quality Control and Authentication of Argan Oils: Application of Advanced Analytical Techniques

et al. 2023

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In addition to the nutritional and therapeutic benefits, Argan oil is praised for its unique bio-ecological and botanic interest. It has been used for centuries to treat cardiovascular issues, diabetes, and skin infections, as well as for its anti-inflammatory and antiproliferative properties. Argan oil is widely commercialized as a result of these characteristics. However, falsifiers deliberately blend Argan oil with cheaper vegetable oils to make economic profits. This reduces the quality and might result in health issues for consumers. Analytical techniques that are rapid, precise, and accurate are employed to monitor its quality, safety, and authenticity. This review provides a comprehensive overview of studies on the quality assessment of Moroccan Argan oil using both untargeted and targeted approaches. To extract relevant information on quality and adulteration, the analytical data are coupled with chemometric techniques.

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Section: Argan Oil Quality Control and Authentication Assessmentmentioning

confidence: 99%

Quality Control and Authentication of Argan Oils: Application of Advanced Analytical Techniques

et al. 2023

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“…Both FTIR and Raman spectroscopies provide characteristic fundamental vibrations and are applied to the elucidation of molecular structure, whereas NIR spectroscopy is based on molecular overtones and combinations of vibrational modes to measure the absorption of electromagnetic radiation within wavelengths from 750 to 2500 nm [ 55 – 58 ]. On the other hand, NIR spectroscopy as a powerful technique has recently been used for monitoring end-point of many pharmaceutical manufacturing processes, such as granulation, mixing or drying, since the NIR measurement not only requires no or little sample preparation but also is fast for online process control [ 59 , 60 ].…”

Section: The Most Commonly Used Solid-state Analysis Of Apis In Drug ...mentioning

confidence: 99%

Current and Potential Applications of Simultaneous DSC-FTIR Microspectroscopy for Pharmaceutical Analysis

Lin¹

2021

Journal of Food and Drug Analysis

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Quality control (QC) is the most important key issue in the pharmaceutical industry to ensure the quality of drug products. Many analytical instruments and techniques in pharmaceutical analysis are applied to assess the quality and quantity of the drugs. In the current and future trends, a combination of digitization, automation and hyphenation with high throughput on-line performance will be the topics for the future of pharmaceutical QC. The hyphenated analytical techniques have recently received great attention as unique means to solve complex analytical problems in a short period of time. This review article is an update on the recent potential applications of hyphenated technique developed from the coupling of a rapid separation or induction technique (differential scanning calorimetry; DSC) and an on-line spectroscopic (Fourier transform infrared; FTIR) detection technology to carry out an one-step solid-state analysis in pharmaceutical formulation developments, including (1) intramolecular condensation of pharmaceutical polymers, (2) intramolecular cyclization of drugs and sweetener, (3) polymorphic transformation of drugs and excipients, (4) drug-polymer (excipient) interaction, (5) fast cocrystal screening and formation. This simultaneous DSC-FTIR microspectroscopy can also provide an easy and direct method for one-step screening and qualitative detection of drug stability in real time.

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“…By absorbing infrared radiation by molecules, the vibrational energy of the binders between atoms changes. It is thus possible to identify the functional groups present in the chemical structure of the analyzed substances [1]. There are two important groups of vibration: stretching and bending vibrations [2].…”

Section: Introductionmentioning

confidence: 99%

Vibrational analysis of hallucinogenic amphetamines

Darie

Praisler

2022

Ann_UGAL_Math_Phys_Mec

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Vibrational spectroscopy represents a very useful technique that measures the interaction of infrared radiation with materials by absorption, emission, or reflection. It is a very powerful way to investigate and identify chemical compounds or functional groups that exist in solid, liquid, or gaseous forms. It can also be used to characterize and identify chemical compounds. This paper presents the vibrational analysis of some representative 2C-x and DOx hallucinogenic amphetamines.

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Vibrational Spectroscopy Applications in Drugs Analysis

Cited by 17 publications

References 25 publications

Quality Control and Authentication of Argan Oils: Application of Advanced Analytical Techniques

Quality Control and Authentication of Argan Oils: Application of Advanced Analytical Techniques

Current and Potential Applications of Simultaneous DSC-FTIR Microspectroscopy for Pharmaceutical Analysis

Vibrational analysis of hallucinogenic amphetamines

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