Vicryl (polyglactin 910) mesh as a dural substitute

Abstract

Many substances have been used as dural substitutes. Although the various materials are effective in a variety of settings, a material that is absorbed over time, elicits minimal inflammatory reaction, is relatively inexpensive, and is easily manipulated would be beneficial. An experimental project was conducted involving closure of dural defects in dogs with a Vicryl (polyglactin 910) mesh graft. Macroscopic and histological examination performed at various times after placement revealed resorption of the graft material, little cerebromembranous adhesion formation, and complete lack of injury to subjacent cortical zones. A substantial neomembrane forms over the zone of the mesh graft. The authors suggest that Vicryl mesh has significant potential as an absorbable, minimally reactive dural substitute.

A simplified technique for intrathoracic stomach repair: laparoscopic fundoplication with Vicryl mesh and BioGlue crural reinforcement

“…The Vicryl mesh used is an absorbable material made of polyglactin, which has a degradation time of 6 to 8 weeks. It has been used with good results in pelvic floor reconstruction, splenorraphy, and closure of dural defects [26][27][28][29]. When similar material was used as an onlay to reinforce abdominal wound closures, wound strength has been shown to increase compared with primary closure alone [30].…”

High early strength calcium phosphate bone cement: Effects of dicalcium phosphate dihydrate and absorbable fibers

“…14,24,41 The suture fibers were chosen because a previous clinical study showed that these fibers had significant potential as an absorbable dural substitute with minimal inflammatory reaction. 42 These large-diameter fibers provided significant strength and toughness to the implant for several weeks. 24 Then, long cylindrical macropores of 293 Ϯ 46 m in diameter were created in CPC after fiber dissolution.…”

Long-term follow-up of blowout fractures of the orbital floor reconstructed with a polyglactin 910/PDS implant

“…It is reported to be completely resorbed after a period of three months. The material is replaced with fibrous collagenous tissue, and minimal inflammation is associated with this process [14,[19][20][21][22]. Subsequently, indications for its use were extended to the orbital floor [6,14].…”