Vincristine-loaded polymeric corona around gold nanorods for combination (chemo-photothermal) therapy of oral squamous carcinoma

Darwish, Wael M.; Abdoon, Ahmed S.; Shata, Mona S.; El-Mansy, Merhan N.

doi:10.1016/j.reactfunctpolym.2020.104575

Cited by 15 publications

(7 citation statements)

References 28 publications

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“…Over the past years, the nanoparticle shapes of rod ( Nakayama et al, 2015 ), belt ( Talloj et al, 2020 ), wire ( Hu et al, 2021 ), sheet ( Mutalik et al, 2022 ), bipyramid ( Yougbaré et al, 2021 ), triangle ( Kuwahara et al, 2020 ), hexagon ( Yong et al, 2021 ), disc ( Chen et al, 2020 ), cube ( Wang et al, 2021 ), octahedron ( Park et al, 2018 ), tripod ( Feng et al, 2020 ), star ( Spedalieri et al, 2021 ), thorn ( Li et al, 2020a ), and tetrapod ( Qiu and Yang, 2007 ) have been synthesized for different applications. For example, gold nanorods have been widely used in photothermal therapy because of their surface plasmon peaks in the near-infrared laser in comparison to nanospheres ( Darwish et al, 2020 ). In particular, the shape-effect research studies are mainly dependent on metal or metal oxide nanoparticles such as gold and silver because they are easily controlled ( Zhu et al, 2016 ; Chakraborty and Parak, 2019 ).…”

Section: Introductionmentioning

confidence: 99%

Fucoidan-Mediated Anisotropic Calcium Carbonate Nanorods of pH-Responsive Drug Release for Antitumor Therapy

Wang

Tong

Luo

et al. 2022

Front. Bioeng. Biotechnol.

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The shape of nanoparticles can determine their physical properties and then greatly impact the physiological reactions on cells or tissues during treatment. Traditionally spherical nanoparticles are more widely applied in biomedicine but are not necessarily the best. The superiority of anisotropic nanoparticles has been realized in recent years. The synthesis of the distinct-shaped metal/metal oxide nanoparticles is easily controlled. However, their biotoxicity is still up for debate. Hence, we designed CaCO3 nanorods for drug delivery prepared at mild condition by polysaccharide-regulated biomineralization in the presence of fucoidan with sulfate groups. The CaCO3 nanorods with a pH sensitivity–loaded antitumor drug mitoxantrone hydrochloride (MTO) showed excellent antitumor efficacy for the HeLa cells and MCF-7 cells in vitro. We believe that anisotropic nanoparticles will bring forth an emblematic shift in nanotechnology for application in biomedicine.

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Section: Introductionmentioning

confidence: 99%

Fucoidan-Mediated Anisotropic Calcium Carbonate Nanorods of pH-Responsive Drug Release for Antitumor Therapy

Wang

Tong

Luo

et al. 2022

Front. Bioeng. Biotechnol.

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“…Similarly, Darwish et al, formulated a phytochemical anticancer agent vincristine conjugated GDNDs (VC@ GDNDs) [ 155 ]. Vincristine injection exhibits great effectiveness against oral cancer upon intralesional administration [ 156 ].…”

Section: Gold Nanoparticles For Combating Cancermentioning

confidence: 99%

Gold nanoparticles and gold nanorods in the landscape of cancer therapy

et al. 2023

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Cancer is a grievous disease whose treatment requires a more efficient, non-invasive therapy, associated with minimal side effects. Gold nanoparticles possessing greatly impressive optical properties have been a forerunner in bioengineered cancer therapy. This theranostic system has gained immense popularity and finds its application in the field of molecular detection, biological imaging, cancer cell targeting, etc. The photothermal property of nanoparticles, especially of gold nanorods, causes absorption of the light incident by the light source, and transforms it into heat, resulting in tumor cell destruction. This review describes the different optical features of gold nanoparticles and summarizes the advance research done for the application of gold nanoparticles and precisely gold nanorods for combating various cancers including breast, lung, colon, oral, prostate, and pancreatic cancer.

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“…Combinational drug treatment is recognized as advanced therapeutic benefits for the targeted drug delivery system that allows for the reduced toxicity and improved therapeutic efficacy. Darwish et al prepared a combinational chemo-photothermal therapy with vincristine (VCR) as phytochemical anticancer and plasmonic gold nanorods (GNRs) as photothermal reagents for the OSCC therapy (Darwish et al, 2020). Based on the self-assembly of amphiphilic poly (DL-lactide-co-glycolide) (PLGA)-PEG polymers, VCR was physically encapsulated into the polymeric corona through the chem-covalently assembly around silica coated gold nanorods (GNRs).…”

Section: Combinational (Polymeric-inorganic) Nanoparticles For Oral Cmentioning

confidence: 99%

mentioning

confidence: 99%

Current Trends of Targeted Drug Delivery for Oral Cancer Therapy

Zhang

Liang

Yang

et al. 2020

Front. Bioeng. Biotechnol.

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Oral cancer is an aggressive tumor that invades the local tissue and can cause metastasis and high mortality. Conventional treatment strategies, e.g., surgery, chemotherapy, and radiation therapy alone or in combinations, possess innegligible issues, and significant side and adverse effects for the clinical applications. Currently, targeting drug delivery is emerging as an effective approach for oral delivery of different therapeutics. Herein we provide a state-of-the-art review on the current progress of targeting drug delivery for oral cancer therapy. Variously oral delivery systems including polymeric/inorganic nanoparticles, liposomes, cyclodextrins, nanolipids, and hydrogels-based forms are emphasized and discussed, and biomimetic systems with respect to oral delivery like therapeutic vitamin, exosomes, proteins, and virus-like particles are also described with emphasis on the cancer treatment. A future perspective is also provided to highlight the existing challenges and possible resolution toward clinical translation of current oral cancer therapies.

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Vincristine-loaded polymeric corona around gold nanorods for combination (chemo-photothermal) therapy of oral squamous carcinoma

Cited by 15 publications

References 28 publications

Fucoidan-Mediated Anisotropic Calcium Carbonate Nanorods of pH-Responsive Drug Release for Antitumor Therapy

Fucoidan-Mediated Anisotropic Calcium Carbonate Nanorods of pH-Responsive Drug Release for Antitumor Therapy

Gold nanoparticles and gold nanorods in the landscape of cancer therapy

Current Trends of Targeted Drug Delivery for Oral Cancer Therapy

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