Viral Hepatitis in Continuous Ambulatory Peritoneal Dialysis Patients in an Endemic Area for Hepatitis B and C Infection: The Taiwan Experience

Abstract

The prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), and their associations in 64 continuous ambulatory peritoneal dialysis (CAPD) patients (30 males and 34 females) were evaluated. A comparison was also made with 526 normal controls (266 males and 260 females). Forty-seven (75%) CAPD patients were anti-HBc positive, with no significant difference to the control group (81.9%). This probably reflects acquisition of HBV infection by CAPD patients before initiation of chronic dialysis therapy in a region hyperendemic for HBV. On the contrary, 11 (17.2%) CAPD patients were anti-HCV positive and 8 (15.2%) were seropositive for both anti-HBc and anti-HCV – much greater prevalence rates compared to those of the control group. The prevalence of anti-HCV correlated with the history and numbers of blood transfusion, and the length of time on previous hemodialysis. A similar correlation occurred in patients with both anti-HBc(+) and anti-HCV(+). In conclusion, in an HBV endemic area such as Taiwan, the prevalence of coexisting HBV and HCV infection in CAPD patients depends on the latter.

Determination of venlafaxine in human plasma by high-performance liquid chromatography using cloud-point extraction and spectrofluorimetric detection

“…Compared with the traditional organic liquid-liquid extraction, this CPE methodology requires a very small amount of relatively non-flammable and non-volatile surfactants. Also, compared with classical organic solvents, it offers the advantages of safety, low cost, high concentration efficiency, easy disposal of surfactants, low toxicity, less environmental pollution and simple procedure [19][20][21][22][23][24][25].…”

Influence of Hepatitis C Virus Infection on Soluble Cellular Adhesion Molecules in Hemodialysis Patients

“…We previously reported that hepatitis C virus (HCV) infection is not uncommon in Asian uremic patients receiving hemodialysis [15][16][17][18] . Studies have shown that HCV infection is an independent risk factor for death in chronic dialysis patients [19,20] .…”

Viral Hepatitis Infection Should Be Considered for Evaluating Uremic Pruritus in Continuous Ambulatory Peritoneal Dialysis Patients

“…Recently, Fisher and Wright [8] noticed an increased prevalence of pruritus in patients of hepatitis C virus (HCV) infection. Viral hepatitis is highly prevalent in dialysis patients [9][10][11][12][13]. Taiwan is one of the endemic areas with a high prevalence rate of viral hepatitis.…”

“…Taiwan is one of the endemic areas with a high prevalence rate of viral hepatitis. In our previous work [11][12][13], we have demonstrated a high prevalence rate of hepatitis B virus (HBV) and HCV infection in our dialysis patients.…”