Abstract:TXThalassemia, a hemoglobinopathy which is common in Asian descendants, in its severe forms, has a poor prognosis. Allogeneic stem cell transplantation (allo-SCT) in severe thalassemia patients is an only way to cure the disease, however available HLA-matched donors for the patients were hardly identified. We recently reported an alternative strategy, pre-transplant immunosuppression (PTIS), combination of fludarabine (Flu) and dexamethasone (Dxm), would immunosuppress the patients to facilitate engraftment wh… Show more
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