Virtual Reality platform for functional magnetic resonance imaging in ecologically valid conditions

Gauthier, Baptiste; Albert, Louis; Martuzzi, Roberto; Herbelin, Bruno; Blanke, Olaf

doi:10.1145/3489849.3489894

Cited by 5 publications

(7 citation statements)

References 39 publications

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“…Neural reactivation of the hippocampus during EM retrieval and its link with memory performance has been demonstrated previously ( 10 , 19 , 22 , 73 ). Yet this earlier work presented single or paired stimuli at encoding (i.e., pictures, word cue (72,61), whereas the present results report hippocampal reinstatement in a richer sensory context with action-embedded 3D scenes using immersive VR in fMRI with incidental encoding, closer to encoding conditions in our everyday life.…”

Section: Discussioncontrasting

confidence: 74%

“…For Experiment 1, we used a head-mounted display and for Experiment 2 MRI-compatible system (see methods). Participants were lying down in a mock MR scanner (Experiment 1) or in the MRI scanner and their movements were tracked with the motion tracking system as described in ( 61 ). VR paradigms and experimental procedures were implemented using our custom-build system ExVR (ExVR, https://github.com/BlankeLab/ExVR), performing real time control and visual rendering with realistic lighting and shading and, for Experiment 2, synchronizing MRI acquisition with VR experimental data.…”

Section: Resultsmentioning

confidence: 99%

“…Particular care was given to the progressive VR immersion procedure to build a strong experience of presence in the virtual environments ( 101 , 102 ) and to maintain it throughout the experiment. Because the immersion in VR of participant lying in an MRI scanner is particularly challenging, we based our approach on the work of ( 61 ), including the methods of familiarization with the virtual environment, and embodiment into a virtual body representation ( 103 ).…”

Section: Immersive Virtual Reality With Motion Trackingmentioning

confidence: 99%

“…In Experiment 2, participants were lying down in the MR scanner. We used a similar setup as described in ( 61 ). To summarize, the same tracking system is used but it is provided by six motion-tracking cameras attached to the ceiling of the MRI room to avoid any movement of the camera during the experiment and optical artifacts.…”

Section: Immersive Virtual Reality With Motion Trackingmentioning

confidence: 99%

“…Although not focusing on BSC framework, the work of St. Jacques and colleagues provided preliminary evidence that BSC may impact EM by showing that the retrieval of an event from a 3PP (compared to 1PP) led to poorer recollection of the sensory and perceptual details experienced at encoding, characterized at the neural level by changes in posterior parietal regions (47,48,(51)(52)(53). More recently, other studies showed that events seen from a natural 1PP (54)(55)(56)(57) or with higher body ownership (61), during encoding, were associated with more vivid memories and better memory performance compared to events encoded from the 3PP or without a body view (54)(55)(56)(57). Collectively, these studies suggest that the modulation of BSC during the encoding of an event affects the later retrieval of that event.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Embodiment in episodic memory through premotor-hippocampal coupling

Meyer,

Gauthier,

Stampacchia

et al. 2023

Preprint

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Episodic memory (EM) allows us to remember and relieve past events and experiences, depending on cortical-hippocampal reinstatement involved during encoding. Although it has been claimed that EM is fundamental to establish a sense of self across time, this has never been shown experimentally. Here we combine immersive virtual reality and fMRI and report stronger hippocampal reinstatement for scenes encoded under preserved sense of self, reflecting later recall performance. We further link the sense of self to EM showing that hippocampal reinstatement is coupled with reinstatement in premotor cortex, a key sense of self region. We extend these findings in a severe amnesic patient (caused by bilateral hippocampal damage), whose memory and re-experiencing lacked the normal dependency on the sense of self. Premotor-hippocampal coupling in EM describes how the self at encoding is neurally reinstated during the retrieval of past episodes, enabling a sense of self across time.

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Section: Discussioncontrasting

confidence: 74%

Section: Resultsmentioning

confidence: 99%

Section: Immersive Virtual Reality With Motion Trackingmentioning

confidence: 99%

Section: Immersive Virtual Reality With Motion Trackingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Embodiment in episodic memory through premotor-hippocampal coupling

Meyer,

Gauthier,

Stampacchia

et al. 2023

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

Breathing control, brain, and bodily self-consciousness: Toward immersive digiceuticals to alleviate respiratory suffering

Betka

Adler

Similowski

et al. 2022

Biological Psychology

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Numerosity estimation of virtual humans as a digital-robotic marker for hallucinations in Parkinson’s disease

Albert,

Potheegadoo,

Herbelin

et al. 2024

Nat Commun

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Hallucinations are frequent non-motor symptoms in Parkinson’s disease (PD) associated with dementia and higher mortality. Despite their high clinical relevance, current assessments of hallucinations are based on verbal self-reports and interviews that are limited by important biases. Here, we used virtual reality (VR), robotics, and digital online technology to quantify presence hallucination (vivid sensations that another person is nearby when no one is actually present and can neither be seen nor heard) in laboratory and home-based settings. We establish that elevated numerosity estimation of virtual human agents in VR is a digital marker for experimentally induced presence hallucinations in healthy participants, as confirmed across several control conditions and analyses. We translated the digital marker (numerosity estimation) to an online procedure that 170 PD patients carried out remotely at their homes, revealing that PD patients with disease-related presence hallucinations (but not control PD patients) showed higher numerosity estimation. Numerosity estimation enables quantitative monitoring of hallucinations, is an easy-to-use unobtrusive online method, reaching people far away from medical centers, translating neuroscientific findings using robotics and VR, to patients’ homes without specific equipment or trained staff.

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Virtual Reality platform for functional magnetic resonance imaging in ecologically valid conditions

Cited by 5 publications

References 39 publications

Embodiment in episodic memory through premotor-hippocampal coupling

Embodiment in episodic memory through premotor-hippocampal coupling

Breathing control, brain, and bodily self-consciousness: Toward immersive digiceuticals to alleviate respiratory suffering

Numerosity estimation of virtual humans as a digital-robotic marker for hallucinations in Parkinson’s disease

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