Viruses and Head and Neck Cancers

Maitra, Radhashree

doi:10.21767/2572-2107.100003

Cited by 4 publications

(4 citation statements)

References 8 publications

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“…; (ii) oropharyngeal squamous cell carcinomas (OPSCCs), which are cancers arising from the base of the tongue, soft palate, tonsils, back of the throat; (iii) squamous cell carcinoma of the larynx (LSCC), which arises from the supraglottic, vocal, and subglottic regions; (iv) nasal squamous cell carcinoma (NSCC; to a lesser extent), which arises from squamous epithelial cells lining the nasal cavity and paranasal sinuses. 14,15 Factors such as alcohol consumption, tobacco smoking and/or chewing increase the risk of HNC. 16,17 Alcohol consumption is associated with ~5% of HNC cases, tobacco use is associated with ~34%, and alcohol combined with tobacco use is associated with 36% of ~HNC cases [5,7,9]; thus ~75% of HNC (i.e.…”

Section: Intraductionmentioning

confidence: 99%

Manifestations of Sexually Transmitted Infections in the Oral Cavity

Kocharyan¹

2023

JBSMFS

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Sexually transmitted diseases аre transmitted in the oral cavity through various forms of sexual activity. This article discusses the relevant clinical manifestations of several sexually transmitted viruses, including human papillomavirus, chlamydia trachomatis, and gonorrhea. Oral manifestations of these infections include ulcerative, inflammatory, or papillomatous lesions of the lips, tongue, mucous membranes, and throat, and may also present with oropharyngeal cancer. The literature review used the databases Google Scholar, PubMed, Scopus, Web of Science.

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Section: Intraductionmentioning

confidence: 99%

Manifestations of Sexually Transmitted Infections in the Oral Cavity

Kocharyan¹

2023

JBSMFS

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“…The incidence of mucosal HNC is relatively low in developed countries and in Australia accounts for some 3% of new cancer diagnoses annually. 11 Although 5-year survival rates have improved to 70% between 2009 and 2013, 11 56% are diagnosed at advanced stage, 12 and patients in regional and remote Australia have a greater risk of advanced disease at presentation compared with their metropolitan (urban) counterparts. 13 Few studies have reported on rates of health literacy in patients with HNC in Australia, with one study 14 reporting 12.0%-17.2% of patients with lung or HNC had low or limited health literacy, depending on which health literacy instrument was used.…”

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confidence: 99%

Associations between patient‐level health literacy and diagnostic time intervals for head and neck cancer: A prospective cohort study

Venchiarutti,

Clark,

Palme

et al. 2024

Head & Neck

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BackgroundHealth literacy (HL) comprises skills and knowledge required to understand, access, and make decisions about healthcare. Our aim was to examine associations between patient HL and time intervals (defined in the Aarhus statement) along the pathway to treatment of head and neck cancer (HNC).MethodsA prospective cohort study was conducted from October 2018 to March 2020. Participants completed the Health Literacy Questionnaire (HLQ®) and described key events and dates along the pathway to treatment using validated questionnaires. Correlations between six diagnostic time intervals and domains of HL were explored, and factors predicting exceeding maximum acceptable timeframes were assessed using logistic regression.ResultsOne hundred patients with a diagnosis of HNC within the preceding 6 months were recruited. HLQ® Domain 2 (sufficient information to manage health) was significantly negatively associated with four intervals: the patient interval (first symptom to first presentation), primary care interval (first presentation to referral to secondary care), diagnostic interval (first presentation to diagnosis), and total interval (first symptom to treatment onset); correlation coefficients −0.25 to −0.27 (P < 0.05). Domain 8 (ability to find good information) was significantly negatively associated with three intervals (primary care interval, diagnostic interval, and total interval; correlation coefficients −0.23 to −0.34; P < 0.05). Higher education, age, and comorbidity levels were associated with shorter patient and diagnostic intervals.ConclusionsHL may be a potential target to improve timeliness of HNC diagnosis and reduce disparities in outcomes.

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confidence: 99%

“…Head and neck cancer (HNC) is a relatively uncommon cancer in Australia, accounting for 3.1% of new cancer diagnoses in 2018 (Cancer Australia, 2018). Though 5-year survival rates have improved to 70% between 2009and 2013(Cancer Australia, 2018, 56% and 13% of cases are diagnosed as advanced and unknown stage, respectively (Cancer Institute of NSW, 2022), and patients in regional and remote Australia have a greater risk of advanced or unknown stage of disease compared to their metropolitan (urban) counterparts (Jong et al, 2004). Reasons for this variation are unclear but likely include patient, health system, and disease factors (Walter et al, 2012) such as poor symptom appraisal and help-seeking by patients, insufficient access to and investigation in primary care, delayed referral to specialists for definitive treatment or poor communication between treating sites for regional patients treated at multiple centres.…”

mentioning

confidence: 99%

A qualitative exploration of the facilitators and barriers to early diagnosis and treatment of head and neck cancer: Perceptions of patients and carers

Venchiarutti

Pho

Clark

et al. 2022

European J Cancer Care

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Objective: The objective of this study to explore experiences of patients and carers of the pathway to diagnosis and treatment of head and neck cancer (HNC), focusing on differences based on remoteness of residence.Methods: Patients ≥6 months post-treatment completion, and their carers, were recruited. Semi-structured interviews, guided by the Model of Pathways to Treatment as the theoretical framework, were conducted to examine pathways to treatment of HNC and facilitators and barriers to early diagnosis and treatment. Thematic analysis with an iterative and data-driven approach was used to identify themes.Results: A total of 39 patients and 17 carers participated in the interviews. Facilitators of timely diagnosis and treatment included a sense of urgency from health care professionals (HCPs), advocacy by the HCP or carers, and leveraging social capital.Distance to services, financial costs, and a perceived lack of emotional investment by HCPs arose as barriers to timely diagnosis and treatment. Participants were often able to rationalise that not all delays were negative, depending causes and expected impact on cancer management. Conclusion:The findings highlight the complex nature of factors facilitating and impeding early HNC diagnosis and treatment that may be targeted in interventions to support patients and meet important benchmarks for high-quality cancer care.

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Viruses and Head and Neck Cancers

Cited by 4 publications

References 8 publications

Manifestations of Sexually Transmitted Infections in the Oral Cavity

Manifestations of Sexually Transmitted Infections in the Oral Cavity

Associations between patient‐level health literacy and diagnostic time intervals for head and neck cancer: A prospective cohort study

A qualitative exploration of the facilitators and barriers to early diagnosis and treatment of head and neck cancer: Perceptions of patients and carers

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