Viscoelastic substances in ophthalmology

Liesegang, Thomas J.

doi:10.1016/0039-6257(90)90027-s

Cited by 172 publications

(98 citation statements)

References 79 publications

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“…All of these factors could directly damage a thin layer of mucinous material on the posterior surface of CE (17) . To protect the endothelium during cataract surgery, viscoelastic material maintains the anterior chamber depth, cushions the endothelium from the insertion of an IOL and acts as a barrier against the turbulent surgical environment (18)(19) . Other technologies and techniques have also improved cataract surgery, with reduction of the US energy produced (20)(21)(22)(23) .…”

Section: Discussionmentioning

confidence: 99%

Effect of bevel position on the corneal endothelium after phacoemulsification

Raskin¹,

Paula²,

Cruz³

et al. 2010

Arq. Bras. Oftalmol.

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Purpose: To compare the extent of corneal endothelial (CE) cell loss changes in two groups of eyes submitted to phacoemulsification, with the conventional bevel-up tip position in one eye and with the bevel-down tip position in the fellow eye. Methods: This prospective clinical trial comprised 25 patients with bilateral cataracts subjected to lens removal by phacoemulsification with the conventional bevel-up tip position (GI) in one eye and with the bevel-down tip position (GII) in the fellow eye. The nuclei were graded clinically on the basis of hardness. The endothelial cell count (ECC) was evaluated preoperatively and 1, 3 and 6 months postoperatively. Total surgical time, effective ultrasound time and complications were also compared between the groups. Statistical analysis was performed by the Tukey Studentized Range test, with repeated measures for the selected periods. For the other parameters a paired t test was used. Data are presented as mean ± SD, with the level of significance set at p<0.05. Results: The mean effective ultrasound time was 8.08 ± 6.75 seconds in group I and 7.00 ± 5.75 seconds in GII (P=0.1792) and total surgical time was 10.01 ± 2.46 minutes in GI and 9.86 ± 2.17 minutes in GII (p=0.6267), respectively. The paired t test revealed no statistical differences between the groups. Complications were also similar between the groups. Mean endothelial cell count loss was 6.9% in GI and 2.8% in GII at one month; 6.9% in GI and 3.6% in GII at three months and 11.9% in GI and 7.6% in GII at six months postoperatively. Comparison of endothelial cell count (ECC) showed a statistically significant difference between the groups during the postoperative period. Conclusion:The conventional bevel-up tip position has a negative effect on corneal endothelial cells compared with the bevel-down position. Since the results of other surgical parameters were similar, the bevel-down tip position should be considered as an option in non-complicated phacoemulsification. Keywords: Cataract extraction; Phacoemulsification/methods; Endothelium, corneal/surgery; Comparative study RESUMO Objetivo: Comparamos duas técnicas de cirurgia de catarata. A técnica cirúr-gica tradicional, em que direciona a abertura do bisel da ponteira de facoemulsificação para o endotélio corneano, com a técnica oposta, onde a reversão da posição de abertura permite o direcionamento da energia de emulsificação para o núcleo. Estudamos seus efeitos sobre a córnea e possíveis complicações. Métodos: O trabalho foi divido em quatro tempos: pré-operatório e após 30, 60 e 180 dias. Os pacientes foram divididos em dois grupos: o grupo 1, tratado com a técnica cirúrgica tradicional, com a abertura da ponteira direcionada para o endotélio, e grupo 2, que recebeu tratamento com técnica oposta, direcionada diretamente para o núcleo ou para os fragmentos nucleares. Após as cirurgias, foram estudados: perda endotelial após 30, 60 e 180 dias, tempo total de cirurgia e tempo efetivo de faco. Resultados: Os resultados intraoperatórios apresentaram...

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Section: Discussionmentioning

confidence: 99%

Effect of bevel position on the corneal endothelium after phacoemulsification

Raskin¹,

Paula²,

Cruz³

et al. 2010

Arq. Bras. Oftalmol.

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“…Because of its mechanical protective effect, it is used in cataract, glaucoma and ocular penetrating injury operations. 1 Furthermore, it is known that HA inhibits the attachment of leukocytes to the intraocular lens and inhibits phagocytosis of macrophages. 3,4 However, there is still considerable debate over its actions.…”

Section: Introductionmentioning

confidence: 99%

Effects of Hyaluronic Acid on the Polymorphonuclear Leukocyte (PMN) Release of Active Oxygen and Protection of Bovine Corneal Endothelial Cells from Activated PMNs

Lym

Suh

Park

2004

Korean J Ophthalmol

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“…Choice of HPMC as the vector phase of BCP granules were realised on its properties and uses in biomedical application. This polymer in solution is used in ophthalmologic surgery for setting intra-ocular lenses (11,12), it can be add to the phosphate calcium cement as to control the rheology (13). But its principal applications are for tablet sealing and binder.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and general properties of silated-hydroxypropyl methylcellulose in prospect of biomedical use

Bourges

Weiss

Daculsi

et al. 2002

Advances in Colloid and Interface Science

113

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Synthesis of grafting silane on a hydro soluble cellulose ether (HPMC) was described. In alkaline medium, this derivate is under gel form. With a decrease of the pH, a self-hardening occurs due to the silanol condensation. For potential biomedical use, we described the silated HPMC synthesis, the gel behavior after steam sterilization and the parameters of the silanol condensation i.e. pH, silane percentage ant temperature. Minimum kinetic of the condensation was observed for pH between 5.5 and 6.5 . So temperature catalyzed the reaction and the selfhardening speed was increased by silane percentage.

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Viscoelastic substances in ophthalmology

Cited by 172 publications

References 79 publications

Effect of bevel position on the corneal endothelium after phacoemulsification

Effect of bevel position on the corneal endothelium after phacoemulsification

Effects of Hyaluronic Acid on the Polymorphonuclear Leukocyte (PMN) Release of Active Oxygen and Protection of Bovine Corneal Endothelial Cells from Activated PMNs

Synthesis and general properties of silated-hydroxypropyl methylcellulose in prospect of biomedical use

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