The investigation of thermal performance in the nanofluids for unsteady boundary layer flow by considering the impacts of suction/injection is a significant research area in the field of fluid dynamics. This flow situation is broadly used in aerodynamics and space sciences as well. The model is formulated for ND-H2O and Ag-H2O nanofluids and then tackled numerically and captured the dynamics of the nanofluids under the multiple flow parameters. From the results, it is investigated that both ND-H2O and Ag-H2O have high thermal performance characteristics. However, higher heat transfer performance is observed for Ag based nanofluid. Further, a graphical and tabular comparison under certain assumptions is provided to authenticate the analysis.