Visible‐Light‐Driven and Self‐Hydrogen‐Donated Nanofibers Enable Rapid‐Deployable Antimicrobial Bioprotection

Abstract

The novel coronavirus SARS‐CoV‐2 has prompted a worldwide pandemic and poses a great threat to public safety and global economies. Most present personal protective equipment (PPE) used to intercept pathogenic microorganisms is deficient in biocidal properties. Herein, we present green nanofibers with effective antibacterial and antiviral activities that can provide sustainable bioprotection by continuously producing reactive oxygen species (ROS). The superiority of the design is that the nanofibers can absorb and store visible light energy and maintain the activity under light or dark environment. Moreover, the nanofibers can uninterruptedly release ROS in the absence of an external hydrogen donor, acting as a biocide under all weather conditions. A facile spraying method is proposed to rapidly deploy the functional nanofibers to existing PPE, such as protective suits and masks. The modified PPE exhibit stable ROS production, excellent capacity for storing activity potential, long‐term durability, and high bactericidal (>99.9%) and viricidal (>99.999%) efficacies.

A Naturally Derived Nanocomposite Film with Photodynamic Antibacterial Activity: New Prospect for Sustainable Food Packaging

“…Visible light (400∼780 nm) is the preferred choice of light source as it is harmless and readily available from solar energy. 10 However, the visible light-driven PDI approach in food packaging has rarely been reported, and the three major barriers are as follows: (i) many PDI systems have poor biocompatibility and are not suitable for food applications; 11 (ii) visible light must be involved in the PDI strategy, 12 so the antibacterial packaging might be limited in dark and weak light conditions; and (iii) most conventional photosensitizers are hydrophobic and tend to aggregate in the packaging substrate, which results in the aggregation-caused quenching (ACQ) behavior and reduced ROS generation. 13 Berberine is a natural isoquinoline alkaloid with hydrophobic cations from herbal plants.…”

“…In particular, photosensitizers generate reactive oxygen species (ROS) after a short period of light exposure, consequently exhibiting stable and broad-spectrum biocidal ability. − By these advantages, it is highly anticipated to apply PDI strategies to food packaging as an efficient antibacterial approach. Visible light (400∼780 nm) is the preferred choice of light source as it is harmless and readily available from solar energy . However, the visible light-driven PDI approach in food packaging has rarely been reported, and the three major barriers are as follows: (i) many PDI systems have poor biocompatibility and are not suitable for food applications; (ii) visible light must be involved in the PDI strategy, so the antibacterial packaging might be limited in dark and weak light conditions; and (iii) most conventional photosensitizers are hydrophobic and tend to aggregate in the packaging substrate, which results in the aggregation-caused quenching (ACQ) behavior and reduced ROS generation …”

Global key concepts of civil-military cooperation for disaster management in the COVID-19 pandemic—A qualitative phenomenological scoping review

“…For medico-scientific contributions to the literature within CIMIC, the military acted in three distinct roles: (1) as subject matter experts, (2) as clinical or experimental investigators or co-investigators, and (3) as co-funders for research ( 22 – 45 ). Military subject matter expertise included telemedicine, digital health technology, critical care medicine, respiratory care, transfusion medicine, as well as global and public health.…”

Photoactivities of Two Vitamin B Derivatives and Their Applications in the Perpetration of Photoinduced Antibacterial Nanofibrous Membranes

“…RF was also used as a photosensitizer to chemically bond with benzophenone anhydride to enhance the photoactivity of the benzophenone compound under daylight irradiation. 15 The excited benzophenone−RF adduct could effectively generate hydroxyl radicals that can nonselectively inactivate Gram-negative and Gram-negative bacteria. Some transition-metal nanoparticles are synthesized with RF to prepare up-conversion photoactive functional materials to kill tumor cells in the photodynamic therapy.…”

“…Besides, the introduction of RF provides the material with an additional antimicrobial function. RF was also used as a photosensitizer to chemically bond with benzophenone anhydride to enhance the photoactivity of the benzophenone compound under daylight irradiation . The excited benzophenone–RF adduct could effectively generate hydroxyl radicals that can nonselectively inactivate Gram-negative and Gram-negative bacteria.…”